ES393421A1 - A method of obtaining derivatives of the penicilanic acid. (Machine-translation by Google Translate, not legally binding)
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A method of obtaining derivatives of the penicilanic acid. (Machine-translation by Google Translate, not legally binding)
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Laboratorios Made SA
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Laboratorios Made SA
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Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
A method for obtaining penicillanic acid derivatives of the general formula: ** (see formula) ** Where x can be hydrogen, metals or physiologically acceptable organic bases, characterized by the passage of gaseous formaldehyde through a suspension of d - (-) - alpha-aminophenylacetic acid in an appropriate solvent at temperatures between -5 and + 40º c, with strong stirring which is maintained for a certain time, after which a tertiary amine is added followed by the slow addition of the stoichiometric amount of ethyl chloroformate dissolved in the reaction solvent, then cooling and adding a mixture of acid 6-aminopenicillanic and a base dissolved in water, allowing the temperature to rise to 0º, after which the aqueous solution is washed with an organic solvent and lyophilized. (Machine-translation by Google Translate, not legally binding)
ES393421A1971-07-191971-07-19A method of obtaining derivatives of the penicilanic acid. (Machine-translation by Google Translate, not legally binding)
ExpiredES393421A1
(en)
A procedure for the obtaining of new derivatives of the 6-amino-penicilanico acid and its salts. (Machine-translation by Google Translate, not legally binding)
Process of production of an N- (5-nitro-2-furil) hydracide alkyliden of formula o2no-ch = N-a i " (Machine-translation by Google Translate, not legally binding)
Chemical compounds process for preparing said compounds and process for preparing 6-(p-hydroxyphenyl-glycylamido)-penam or 7-(p-hydroxyphenyl-glycylamido)-cephem compounds