ES393303A1 - Procedure for the preparation of methyl-piperazine derivatives. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the preparation of methyl-piperazine derivatives. (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Spofa Vereinigte Pharma Werke
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Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Spofa Vereinigte Pharma Werke
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Priority to ES393303ApriorityCriticalpatent/ES393303A1/en
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Process for the preparation of methyl piperazine derivatives of the general formula i ** (see formula) ** Wherein x means a sulfur or oxygen atom or a methylene group and r means a hydrogen or halogen atom, an alkyl radical, alkoxy, an alkylthio group, an alkyl silylene or an alkanesulphonyl group having 1 to 5 carbon atoms, or a benzyloxy or dimethylsulfamyl group, and their salts, by reduction of ethoxycarbonylpiperazine derivatives of the general formula xii ** (see formula) ** Wherein x and r mean the same as in formula i, with complex hydrides and optionally by neutralization of the resulting bases of the general formula i with organic or inorganic acids with formation of corresponding salts, characterized in that the reduction is carried out using sodium hydride-di (2-methoxyethoxy) -aluminum as a reducing agent. (Machine-translation by Google Translate, not legally binding)
ES393303A1971-07-151971-07-15Procedure for the preparation of methyl-piperazine derivatives. (Machine-translation by Google Translate, not legally binding)
ExpiredES393303A1
(en)
Benzylamine derivatives process for science union et cie benzylamine derivatives process for their production and pharmaceutical compositions containing them