ES393022A1 - Procedure for the preparation of adenosin-5'-carboxylic acid derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of adenosin-5'-carboxylic acid derivatives. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES393022A1 ES393022A1 ES393022A ES393022A ES393022A1 ES 393022 A1 ES393022 A1 ES 393022A1 ES 393022 A ES393022 A ES 393022A ES 393022 A ES393022 A ES 393022A ES 393022 A1 ES393022 A1 ES 393022A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- translation
- procedure
- preparation
- legally binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
Procedure for the preparation of derivatives of adenosine-5'-carboxylic acids of the general formula I ** (See formula) ** in which R1 and R2 signify hydrogen, a hydroxyl, amino, lower alcoholic group, lower alkenyl, optionally N-alcoholyl lower aminoalcohyl group, a cycloalkyl or hydroxyalkyl group or a pipBridino radical or R1 and R2 together signify an alcoholic group with 4 to 7 carbon atoms, which may eventually be interrupted by an oxygen or sulfur atom or by an imino, alcoholimino or arylimino group, and Z means two hydrogen atoms or a lower alcoholic group, as well as their pharmacologically compatible salts, characterized by which reactive derivatives of adenosine-S'-carboxylic acids of the general formula II are reacted in a manner known per se ** (See formula) ** in which Z has the meanings indicated above, with amines of the general formula III ** (See formula) ** in which R1 and R2 have the meanings indicated above, and eventually they are subsequently transformed into their pharmacologically safe salts. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19702034785 DE2034785A1 (en) | 1970-07-14 | 1970-07-14 | Adenosine 5 carboxylic acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES393022A1 true ES393022A1 (en) | 1973-08-01 |
Family
ID=5776675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES393022A Expired ES393022A1 (en) | 1970-07-14 | 1971-07-08 | Procedure for the preparation of adenosin-5'-carboxylic acid derivatives. (Machine-translation by Google Translate, not legally binding) |
Country Status (16)
| Country | Link |
|---|---|
| AT (1) | AT306253B (en) |
| AU (1) | AU449293B2 (en) |
| CA (1) | CA1077931A (en) |
| CH (1) | CH556345A (en) |
| DE (1) | DE2034785A1 (en) |
| ES (1) | ES393022A1 (en) |
| FI (1) | FI54316C (en) |
| FR (1) | FR2100901B1 (en) |
| GB (1) | GB1295228A (en) |
| HU (1) | HU162216B (en) |
| IE (1) | IE35535B1 (en) |
| IL (1) | IL37280A (en) |
| NL (1) | NL7109584A (en) |
| SE (1) | SE378604B (en) |
| YU (1) | YU34533B (en) |
| ZA (1) | ZA714483B (en) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1082695A (en) * | 1972-04-10 | 1980-07-29 | Francis E. Fischer | Process for preparing adenosine-5'-carboxamides |
| US3853846A (en) * | 1973-02-12 | 1974-12-10 | Abbott Lab | INOSINE-5 -Carboxylates |
| US3852268A (en) * | 1973-02-12 | 1974-12-03 | Abbott Lab | Inosine-5 -carboxylic acid amides |
| US3855206A (en) * | 1973-04-11 | 1974-12-17 | Abbott Lab | Adenosine-5{40 -carbohydroxamic esters |
| US3966917A (en) * | 1974-07-30 | 1976-06-29 | Abbott Laboratories | Platelet aggregation inhibitors |
| AT350735B (en) * | 1976-08-06 | 1979-06-11 | Hoffmann La Roche | METHOD FOR PRODUCING NEW RIBO-FURANOSYL IMIDAZOLE DERIVATIVES |
| US4479942A (en) * | 1981-08-10 | 1984-10-30 | Fujisawa Pharmaceutical Co., Ltd. | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof |
| US5278150A (en) * | 1992-04-24 | 1994-01-11 | Whitby Research, Inc. | 2-hydrazoadenosines and their utility for the treatmeat of vascular conditions |
| TW528755B (en) | 1996-12-24 | 2003-04-21 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
| YU44900A (en) | 1998-01-31 | 2003-01-31 | Glaxo Group Limited | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
| PE20060272A1 (en) | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2R, 3R, 4S, 5R, 2'R, 3'R, 4'S, 5'S) -2.2 '- {TRANS-1,4-CYCLOHEXANODIYLBIS- [IMINO (2 - {[2- (1-METHYL- 1H-IMIDAZOL-4-IL) ETHYL] AMINO} -9H-PURIN-6,9-DIYL)]} BIS [5- (2-ETHYL-2H-TETRAZOLE-5-IL) TETRAHYDRO-3,4-FURANODIOL] AS AN A2A AGONIST |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
-
1970
- 1970-07-14 DE DE19702034785 patent/DE2034785A1/en active Pending
-
1971
- 1971-07-07 ZA ZA714483A patent/ZA714483B/en unknown
- 1971-07-08 GB GB1295228D patent/GB1295228A/en not_active Expired
- 1971-07-08 SE SE7108839A patent/SE378604B/xx unknown
- 1971-07-08 ES ES393022A patent/ES393022A1/en not_active Expired
- 1971-07-09 IL IL37280A patent/IL37280A/en unknown
- 1971-07-09 FI FI1963/71A patent/FI54316C/en active
- 1971-07-09 CH CH1013171A patent/CH556345A/en not_active IP Right Cessation
- 1971-07-12 NL NL7109584A patent/NL7109584A/xx not_active Application Discontinuation
- 1971-07-12 YU YU1833/71A patent/YU34533B/en unknown
- 1971-07-12 CA CA118,018A patent/CA1077931A/en not_active Expired
- 1971-07-13 AU AU31159/71A patent/AU449293B2/en not_active Expired
- 1971-07-13 FR FR7125625A patent/FR2100901B1/fr not_active Expired
- 1971-07-13 AT AT611371A patent/AT306253B/en not_active IP Right Cessation
- 1971-07-13 IE IE884/71A patent/IE35535B1/en unknown
- 1971-07-13 HU HUBO1304A patent/HU162216B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA1077931A (en) | 1980-05-20 |
| AU3115971A (en) | 1973-01-18 |
| FR2100901B1 (en) | 1974-11-15 |
| HU162216B (en) | 1973-01-29 |
| IL37280A0 (en) | 1971-10-20 |
| FI54316B (en) | 1978-07-31 |
| ZA714483B (en) | 1972-04-26 |
| SE378604B (en) | 1975-09-08 |
| YU34533B (en) | 1979-09-10 |
| AT306253B (en) | 1973-04-10 |
| IL37280A (en) | 1974-03-14 |
| FR2100901A1 (en) | 1972-03-24 |
| IE35535L (en) | 1972-01-14 |
| IE35535B1 (en) | 1976-03-18 |
| GB1295228A (en) | 1972-11-08 |
| FI54316C (en) | 1978-11-10 |
| DE2034785A1 (en) | 1972-01-20 |
| AU449293B2 (en) | 1974-06-06 |
| YU183371A (en) | 1979-02-28 |
| NL7109584A (en) | 1972-01-18 |
| SU385448A3 (en) | 1973-05-29 |
| CH556345A (en) | 1974-11-29 |
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