ES392912A1 - Procedimiento para la preparacion de 5 - fenil - 3h -1,4 - benzodiazepinas sustituidas. - Google Patents
Procedimiento para la preparacion de 5 - fenil - 3h -1,4 - benzodiazepinas sustituidas.Info
- Publication number
- ES392912A1 ES392912A1 ES392912A ES392912A ES392912A1 ES 392912 A1 ES392912 A1 ES 392912A1 ES 392912 A ES392912 A ES 392912A ES 392912 A ES392912 A ES 392912A ES 392912 A1 ES392912 A1 ES 392912A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- see formula
- benzodiazepines
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229940049706 benzodiazepine Drugs 0.000 title 1
- 150000001557 benzodiazepines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- -1 methoxy, ethoxy Chemical group 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 abstract 1
- DBFLXAXACNTBEP-UHFFFAOYSA-N 5-phenyl-3h-1,4-benzodiazepine Chemical class N=1CC=NC2=CC=CC=C2C=1C1=CC=CC=C1 DBFLXAXACNTBEP-UHFFFAOYSA-N 0.000 abstract 1
- LGRFSURHDFAFJT-UHFFFAOYSA-N Phthalic anhydride Natural products C1=CC=C2C(=O)OC(=O)C2=C1 LGRFSURHDFAFJT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002877 alkyl aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- JHIWVOJDXOSYLW-UHFFFAOYSA-N butyl 2,2-difluorocyclopropane-1-carboxylate Chemical compound CCCCOC(=O)C1CC1(F)F JHIWVOJDXOSYLW-UHFFFAOYSA-N 0.000 abstract 1
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
- 125000002576 diazepinyl group Chemical class N1N=C(C=CC=C1)* 0.000 abstract 1
- IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 abstract 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 238000007363 ring formation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AR23309070 | 1970-12-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES392912A1 true ES392912A1 (es) | 1974-07-01 |
Family
ID=3461858
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES392912A Expired ES392912A1 (es) | 1970-12-21 | 1971-07-05 | Procedimiento para la preparacion de 5 - fenil - 3h -1,4 - benzodiazepinas sustituidas. |
Country Status (4)
| Country | Link |
|---|---|
| BE (1) | BE772825A (enrdf_load_html_response) |
| CH (1) | CH573929A5 (enrdf_load_html_response) |
| DE (1) | DE2159920A1 (enrdf_load_html_response) |
| ES (1) | ES392912A1 (enrdf_load_html_response) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1087017B (it) * | 1977-10-18 | 1985-05-31 | Ravizza Spa | Processo per la preparazione di un 7-cloro-5-(2-clorofenil)-benzodiaze pinone |
| BRPI0901298A2 (pt) * | 2009-04-06 | 2011-01-04 | Ems Sa | derivados ftalimìdicos de compostos antiinflamatórios não-esteróide e/ou moduladores de tnf-(alfa), processo de sua obtenção, composições farmacêuticas contendo os mesmos e seus usos no tratamento de doenças inflamatórias |
-
1971
- 1971-07-05 ES ES392912A patent/ES392912A1/es not_active Expired
- 1971-09-20 BE BE772825A patent/BE772825A/xx unknown
- 1971-12-02 DE DE19712159920 patent/DE2159920A1/de active Pending
- 1971-12-09 CH CH1793971A patent/CH573929A5/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BE772825A (fr) | 1972-01-17 |
| CH573929A5 (enrdf_load_html_response) | 1976-03-31 |
| DE2159920A1 (de) | 1972-06-29 |
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