ES392167A1 - Procedimiento para la produccion de aminofenilamidinas. - Google Patents
Procedimiento para la produccion de aminofenilamidinas.Info
- Publication number
- ES392167A1 ES392167A1 ES392167A ES392167A ES392167A1 ES 392167 A1 ES392167 A1 ES 392167A1 ES 392167 A ES392167 A ES 392167A ES 392167 A ES392167 A ES 392167A ES 392167 A1 ES392167 A1 ES 392167A1
- Authority
- ES
- Spain
- Prior art keywords
- production
- medicinal use
- aminophenylamidine
- hydrolysis
- aminophenylamidines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000007062 hydrolysis Effects 0.000 abstract 2
- 238000006460 hydrolysis reaction Methods 0.000 abstract 2
- CBCKQZAAMUWICA-UHFFFAOYSA-N 1,4-phenylenediamine Chemical compound NC1=CC=C(N)C=C1 CBCKQZAAMUWICA-UHFFFAOYSA-N 0.000 abstract 1
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 abstract 1
- 239000002262 Schiff base Substances 0.000 abstract 1
- 150000004753 Schiff bases Chemical class 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 230000000507 anthelmentic effect Effects 0.000 abstract 1
- 229940124339 anthelmintic agent Drugs 0.000 abstract 1
- 239000000921 anthelmintic agent Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- AEOCXXJPGCBFJA-UHFFFAOYSA-N ethionamide Chemical compound CCC1=CC(C(N)=S)=CC=N1 AEOCXXJPGCBFJA-UHFFFAOYSA-N 0.000 abstract 1
- PAXRVGDTBDATMF-UHFFFAOYSA-N n,n-dimethylethanimidamide Chemical compound CN(C)C(C)=N PAXRVGDTBDATMF-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/195—Radicals derived from nitrogen analogues of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/14—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2029299A DE2029299C3 (de) | 1970-06-13 | 1970-06-13 | Neue Aminophenylamidine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES392167A1 true ES392167A1 (es) | 1974-02-01 |
Family
ID=5773921
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES392167A Expired ES392167A1 (es) | 1970-06-13 | 1971-06-12 | Procedimiento para la produccion de aminofenilamidinas. |
| ES402622A Expired ES402622A1 (es) | 1970-06-13 | 1972-05-10 | Procedimiento para la produccion de aminofenilamidinas. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES402622A Expired ES402622A1 (es) | 1970-06-13 | 1972-05-10 | Procedimiento para la produccion de aminofenilamidinas. |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US3855292A (en, 2012) |
| JP (7) | JPS5813537B1 (en, 2012) |
| AT (1) | AT312580B (en, 2012) |
| BE (1) | BE768403A (en, 2012) |
| CA (1) | CA930365A (en, 2012) |
| CH (3) | CH571480A5 (en, 2012) |
| CS (2) | CS171700B2 (en, 2012) |
| DD (1) | DD95085A5 (en, 2012) |
| DE (1) | DE2029299C3 (en, 2012) |
| DK (1) | DK129339B (en, 2012) |
| ES (2) | ES392167A1 (en, 2012) |
| FR (1) | FR2100757B1 (en, 2012) |
| GB (1) | GB1325529A (en, 2012) |
| HU (1) | HU162207B (en, 2012) |
| IE (1) | IE35363B1 (en, 2012) |
| IL (1) | IL37025A (en, 2012) |
| NL (1) | NL7108070A (en, 2012) |
| PH (1) | PH9765A (en, 2012) |
| PL (1) | PL77584B1 (en, 2012) |
| RO (2) | RO59039A (en, 2012) |
| SE (1) | SE366301B (en, 2012) |
| SU (1) | SU452092A3 (en, 2012) |
| ZA (1) | ZA713765B (en, 2012) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4018814A (en) * | 1970-06-13 | 1977-04-19 | Bayer Aktiengesellschaft | Aromatic amides and carbomates of phenylamidines |
| US4056631A (en) * | 1973-10-23 | 1977-11-01 | Showa Denko K.K. | Method of combatting ticks |
| JPS5069226A (en, 2012) * | 1973-10-23 | 1975-06-10 | ||
| DE2758005A1 (de) * | 1977-12-24 | 1979-06-28 | Bayer Ag | Phosphonylureidobenzol-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4360466A (en) * | 1981-11-25 | 1982-11-23 | American Cyanamid Company | N'-[2,6-Dichloro-4-(substituted-benzylideneamino)phenyl]-N,N-dimethylformamidines |
| DE3828759A1 (de) * | 1988-08-25 | 1990-03-01 | Bayer Ag | Neue cyclische amidine und verfahren zu ihrer herstellung |
| GB8903592D0 (en) * | 1989-02-16 | 1989-04-05 | Boots Co Plc | Therapeutic agents |
| JPH04134260U (ja) * | 1991-05-24 | 1992-12-14 | 藤和機工株式会社 | 注湯装置 |
| CN100348577C (zh) * | 2004-05-12 | 2007-11-14 | 中国疾病预防控制中心寄生虫病预防控制所 | 一种药用化合物及其驱虫用途 |
| DE102007061262A1 (de) * | 2007-12-19 | 2009-06-25 | Bayer Animal Health Gmbh | Neue Verwendung von Tribendimidin |
| DE102008030764A1 (de) | 2008-06-28 | 2009-12-31 | Bayer Animal Health Gmbh | Kombination von Amidin-Derivaten mit cyclischen Depsipeptiden |
| AU2020221012A1 (en) | 2019-02-15 | 2021-10-07 | Albemarle Corporation | Methods for extracting boron from an organic solution |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3182053A (en) * | 1961-11-20 | 1965-05-04 | Hoffmann La Roche | Pyridine formamidines of primary amines |
| US3189648A (en) * | 1962-04-11 | 1965-06-15 | Du Pont | Process for preparing n, n-dialkyl-n'-arylamidines |
| US3121084A (en) * | 1962-09-17 | 1964-02-11 | Du Pont | Selected n, n, n'-trisubstituted amidines and their preparation by reaction of compounds with-nh2 groups with amide acetals |
| GB1212454A (en) * | 1967-03-04 | 1970-11-18 | Egyt Gyogyszervegyeszeti Gyar | N,n'-substituted formamidines |
-
1970
- 1970-06-13 DE DE2029299A patent/DE2029299C3/de not_active Expired
-
1971
- 1971-06-09 US US00151575A patent/US3855292A/en not_active Expired - Lifetime
- 1971-06-09 SU SU1821450A patent/SU452092A3/ru active
- 1971-06-10 IL IL37025A patent/IL37025A/xx unknown
- 1971-06-10 ZA ZA713765A patent/ZA713765B/xx unknown
- 1971-06-11 FR FR7121385A patent/FR2100757B1/fr not_active Expired
- 1971-06-11 CS CS3637A patent/CS171700B2/cs unknown
- 1971-06-11 SE SE07600/71A patent/SE366301B/xx unknown
- 1971-06-11 NL NL7108070A patent/NL7108070A/xx not_active Application Discontinuation
- 1971-06-11 CH CH857371A patent/CH571480A5/xx not_active IP Right Cessation
- 1971-06-11 CA CA115437A patent/CA930365A/en not_active Expired
- 1971-06-11 GB GB2749571A patent/GB1325529A/en not_active Expired
- 1971-06-11 DK DK286871AA patent/DK129339B/da unknown
- 1971-06-11 CH CH532875A patent/CH572464A5/xx not_active IP Right Cessation
- 1971-06-11 IE IE758/71A patent/IE35363B1/xx unknown
- 1971-06-11 CH CH532975A patent/CH569703A5/xx not_active IP Right Cessation
- 1971-06-11 HU HUBA2599A patent/HU162207B/hu unknown
- 1971-06-11 BE BE768403A patent/BE768403A/xx unknown
- 1971-06-11 AT AT503871A patent/AT312580B/de active
- 1971-06-11 CS CS4324A patent/CS171699B2/cs unknown
- 1971-06-12 PL PL1971148772A patent/PL77584B1/pl unknown
- 1971-06-12 ES ES392167A patent/ES392167A1/es not_active Expired
- 1971-06-12 RO RO67284A patent/RO59039A/ro unknown
- 1971-06-12 RO RO73522A patent/RO59026A/ro unknown
- 1971-06-14 PH PH12538A patent/PH9765A/en unknown
- 1971-06-14 DD DD161366A patent/DD95085A5/xx unknown
- 1971-06-14 JP JP46041736A patent/JPS5813537B1/ja active Granted
-
1972
- 1972-05-10 ES ES402622A patent/ES402622A1/es not_active Expired
-
1980
- 1980-03-06 JP JP2742980A patent/JPS55143957A/ja active Pending
- 1980-03-06 JP JP2742880A patent/JPS55143956A/ja active Granted
- 1980-03-06 JP JP2743080A patent/JPS55143958A/ja active Pending
- 1980-11-19 JP JP16210480A patent/JPS56123968A/ja active Pending
-
1981
- 1981-12-29 JP JP56216189A patent/JPS57131760A/ja active Pending
- 1981-12-29 JP JP56216190A patent/JPS57131761A/ja active Pending
Also Published As
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