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Novartis AG
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Ciba Geigy AG
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Publication of ES391894A1publicationCriticalpatent/ES391894A1/en
C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
C07D501/14—Compounds having a nitrogen atom directly attached in position 7
C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
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Chemical & Material Sciences
(AREA)
Organic Chemistry
(AREA)
Cephalosporin Compounds
(AREA)
Abstract
Process for obtaining amine compounds, in particular 7-amino-cef-3-em-4-carboxylic acid compounds of the formula **(See formula)** wherein R2 means hydrogen or an organic R2A moiety, which together with the group -C (= O) -O forms a protected carboxyl group, or the salts of these compounds, characterized in that a cef-3-em compound of formula **(See formula)** in which Aco means the acyl residue of an organic carboxylic acid, or a salt of a compound thereof with a salt-forming group, is treated with an imidohalide-forming agent, the imidohalide formed is transformed into the corresponding iminoether and this is dissociates, and, if desired, a compound obtained is transformed into another compound of formula I, and/or, if desired, a mixture of obtained isomers is separated into the different isomers. (Machine-translation by Google Translate, not legally binding)
ES391894A1970-06-051971-06-03Procedure for the obtaining of amino compounds. (Machine-translation by Google Translate, not legally binding)
ExpiredES391894A1
(en)
A procedure for preparing 1- (p-acetyphenyl) -2- (2,2-dichloroacetamido) -1,3-propanodiol. (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of acid compounds 7 amino-3-cejem-3-ol-4-carboxilicos O-substitute. (Machine-translation by Google Translate, not legally binding)
Procedure for obtaining a derivative of 1,1-dioxide from 3,4-hydride-1,2,4-benzotiadiacin (Machine-translation by Google Translate, not legally binding)
Procedure for the production of new heterocyclic compounds and their acid addiction salts (Machine-translation by Google Translate, not legally binding)