ES390645A1 - Un procedimiento para la preparacion de un esteroide. - Google Patents
Un procedimiento para la preparacion de un esteroide.Info
- Publication number
- ES390645A1 ES390645A1 ES390645A ES390645A ES390645A1 ES 390645 A1 ES390645 A1 ES 390645A1 ES 390645 A ES390645 A ES 390645A ES 390645 A ES390645 A ES 390645A ES 390645 A1 ES390645 A1 ES 390645A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- derivative
- steroid
- translation
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000003431 steroids Chemical class 0.000 title abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- AMXOYNBUYSYVKV-UHFFFAOYSA-M lithium bromide Chemical compound [Li+].[Br-] AMXOYNBUYSYVKV-UHFFFAOYSA-M 0.000 abstract 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 1
- LCGLNKUTAGEVQW-UHFFFAOYSA-N Dimethyl ether Chemical group COC LCGLNKUTAGEVQW-UHFFFAOYSA-N 0.000 abstract 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
- MUCRYNWJQNHDJH-OADIDDRXSA-N Ursonic acid Chemical compound C1CC(=O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C MUCRYNWJQNHDJH-OADIDDRXSA-N 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000007269 dehydrobromination reaction Methods 0.000 abstract 1
- 239000012467 final product Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- XGZVUEUWXADBQD-UHFFFAOYSA-L lithium carbonate Chemical compound [Li+].[Li+].[O-]C([O-])=O XGZVUEUWXADBQD-UHFFFAOYSA-L 0.000 abstract 1
- 229910052808 lithium carbonate Inorganic materials 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- BXBUVIPNRGDTNE-UHFFFAOYSA-N sodium;hydrobromide Chemical compound [Na].Br BXBUVIPNRGDTNE-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/566—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol having an oxo group in position 17, e.g. estrone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3272370A | 1970-04-28 | 1970-04-28 | |
| US11306771A | 1971-02-05 | 1971-02-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES390645A1 true ES390645A1 (es) | 1974-04-01 |
Family
ID=26708789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES390645A Expired ES390645A1 (es) | 1970-04-28 | 1971-04-27 | Un procedimiento para la preparacion de un esteroide. |
Country Status (12)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030069215A1 (en) | 2001-03-30 | 2003-04-10 | The Government Of The United States Of America, | Methods of making and using 7a,11b-dimethyl-17b-hydroxy-4-estren-3-one 17b-trans-4-n-butylcyclohexane carboxylate and 7a,11b-dimethyl-17b-hydroxyestr-4-en-3-one 17-undecanoate |
| AU2001249661B2 (en) | 2000-03-31 | 2005-02-17 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Methods of making the 4-n-butylcyclohexanoic and the undecanoic acid esters of (7 alpha, 11 beta)-dimethyl-17 beta-hydroxy-4-estren-3-one and their medical use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3374228A (en) * | 1965-10-25 | 1968-03-19 | Syntex Corp | 14beta-estra-1, 3, 5(10)-trienes |
| US3467682A (en) * | 1967-04-28 | 1969-09-16 | Searle & Co | 13beta-alkyl-17alpha-alkynylgon-4-ene-3beta,17beta-diols and esters corresponding |
-
1971
- 1971-04-14 IL IL36628A patent/IL36628A/xx unknown
- 1971-04-20 CA CA110,864A patent/CA943126A/en not_active Expired
- 1971-04-22 DE DE2119708A patent/DE2119708C3/de not_active Expired
- 1971-04-26 CH CH609071A patent/CH567520A5/xx not_active IP Right Cessation
- 1971-04-26 DK DK199371AA patent/DK128209B/da unknown
- 1971-04-27 ES ES390645A patent/ES390645A1/es not_active Expired
- 1971-04-27 SE SE7105427A patent/SE379356B/xx unknown
- 1971-04-27 FR FR7114959A patent/FR2092103A1/fr active Granted
- 1971-04-27 AR AR235240A patent/AR192710A1/es active
- 1971-04-28 NL NL7105798A patent/NL7105798A/xx not_active Application Discontinuation
- 1971-04-28 JP JP2850271A patent/JPS535296B1/ja active Pending
- 1971-04-28 BE BE766396A patent/BE766396A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR192710A1 (es) | 1973-03-14 |
| DE2119708B2 (de) | 1980-07-17 |
| FR2092103A1 (en) | 1972-01-21 |
| DE2119708A1 (de) | 1971-11-11 |
| NL7105798A (enrdf_load_stackoverflow) | 1971-11-01 |
| IL36628A0 (en) | 1971-06-23 |
| DK128209B (da) | 1974-03-18 |
| BE766396A (fr) | 1971-10-28 |
| IL36628A (en) | 1978-08-31 |
| SE379356B (enrdf_load_stackoverflow) | 1975-10-06 |
| FR2092103B1 (enrdf_load_stackoverflow) | 1975-10-10 |
| DE2119708C3 (de) | 1981-10-08 |
| CH567520A5 (enrdf_load_stackoverflow) | 1975-10-15 |
| JPS535296B1 (enrdf_load_stackoverflow) | 1978-02-25 |
| CA943126A (en) | 1974-03-05 |
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