ES390087A1 - Procedure for the obtaining of new 3-guanidinoalquil -tiophenes. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the obtaining of new 3-guanidinoalquil -tiophenes. (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AGfiledCriticalCiba Geigy AG
Publication of ES390087A1publicationCriticalpatent/ES390087A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Procedure for obtaining new 3-guanidinoalkyl-thiophenes of general formula I **(See formula)** wherein each of the residues R1 and R2 signifies hydrogen, lower alkyl or halogen, each of the residues R3 and R4 signifies hydrogen or lower alkyl, each of the residues R5 and R6 signifies hydrogen or lower alkyl, or the residues R5 and R6 together represent lower alkylene, whereby the nitrogen atoms bonded thereto are separated by at least 2 carbon atoms, and n represents a number from 1 to 4, and from their salts, characterized in that a 3-aminoalkyl- thiophene of formula III **(See formula)** or its salts, is reacted with a compound of formula IV **(See formula)** or its salts, wherein X signifies the R6 moiety or X and Y together with the CN double bond form a CN triple bond, or Y signifies a dissociable moiety or an amino or lower alkyl-amino group, and, if desired, a compound obtained is transformed into its salts, or a salt obtained in the corresponding free compound or another salt, and/or, if desired, a mixture of obtained isomers is separated into the different isomers. (Machine-translation by Google Translate, not legally binding)
ES390087A1970-04-131971-04-12Procedure for the obtaining of new 3-guanidinoalquil -tiophenes. (Machine-translation by Google Translate, not legally binding)
ExpiredES390087A1
(en)