ES387494A1 - Procedimiento para la preparacion de nuevos esteres de la 6alfa, 9 alfa-difluoro - 11 beta, 21-dihidroxi-16 alfa, 17 alfa-isopropiliden-dioxi-pregna-1,4-dien - 3,20-diona. - Google Patents

Procedimiento para la preparacion de nuevos esteres de la 6alfa, 9 alfa-difluoro - 11 beta, 21-dihidroxi-16 alfa, 17 alfa-isopropiliden-dioxi-pregna-1,4-dien - 3,20-diona.

Info

Publication number
ES387494A1
ES387494A1 ES387494A ES387494A ES387494A1 ES 387494 A1 ES387494 A1 ES 387494A1 ES 387494 A ES387494 A ES 387494A ES 387494 A ES387494 A ES 387494A ES 387494 A1 ES387494 A1 ES 387494A1
Authority
ES
Spain
Prior art keywords
fluocinolone
acetonide
carboxylic acid
acid esters
heterocyclic carboxylic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES387494A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES387494A1 publication Critical patent/ES387494A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
ES387494A 1970-02-04 1971-01-21 Procedimiento para la preparacion de nuevos esteres de la 6alfa, 9 alfa-difluoro - 11 beta, 21-dihidroxi-16 alfa, 17 alfa-isopropiliden-dioxi-pregna-1,4-dien - 3,20-diona. Expired ES387494A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702005002 DE2005002A1 (da) 1970-02-04 1970-02-04

Publications (1)

Publication Number Publication Date
ES387494A1 true ES387494A1 (es) 1973-05-01

Family

ID=5761386

Family Applications (1)

Application Number Title Priority Date Filing Date
ES387494A Expired ES387494A1 (es) 1970-02-04 1971-01-21 Procedimiento para la preparacion de nuevos esteres de la 6alfa, 9 alfa-difluoro - 11 beta, 21-dihidroxi-16 alfa, 17 alfa-isopropiliden-dioxi-pregna-1,4-dien - 3,20-diona.

Country Status (24)

Country Link
US (1) US3740392A (da)
JP (1) JPS5224016B1 (da)
AT (1) AT301773B (da)
BE (1) BE762487A (da)
BG (1) BG17565A3 (da)
CA (1) CA918635A (da)
CH (1) CH571541A5 (da)
CS (1) CS161769B2 (da)
DE (1) DE2005002A1 (da)
DK (1) DK126424B (da)
ES (1) ES387494A1 (da)
FI (1) FI48584C (da)
FR (1) FR2081489B1 (da)
GB (1) GB1318817A (da)
IE (1) IE34930B1 (da)
IL (1) IL36127A (da)
NL (1) NL7101407A (da)
NO (1) NO135366C (da)
PL (1) PL81653B1 (da)
RO (1) RO56931A (da)
SE (1) SE369715B (da)
SU (1) SU382281A3 (da)
YU (1) YU18371A (da)
ZA (1) ZA71661B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3867528A (en) * 1973-10-11 1975-02-18 American Cyanamid Co Steroidal topical cream base
US3892856A (en) * 1974-04-10 1975-07-01 Squibb & Sons Inc Topical steroid formulation
US3970646A (en) * 1974-04-24 1976-07-20 Ortho Pharmaceutical Corporation Halo-steroidal thioketals
US4221786A (en) * 1978-06-20 1980-09-09 Ciba-Geigy Corporation Novel halogenopregnadienes and process for the manufacture thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3053836A (en) * 1961-07-14 1962-09-11 Olin Mathieson Acetals and ketals of 16alpha, 17alpha-dihydroxyprogesterones
DE1252678B (de) * 1965-06-05 1967-10-26 Dr, Karl Thomae GmbH, Biber ach/Riß Verfahren zur Herstellung neuer Corticosteroid 21ester
US3374230A (en) * 1966-04-26 1968-03-19 Schering Corp Acetylation of steroidal alcohols with ketene

Also Published As

Publication number Publication date
CS161769B2 (da) 1975-06-10
FR2081489A1 (da) 1971-12-03
RO56931A (da) 1975-02-15
YU18371A (en) 1978-10-31
NO135366C (no) 1977-03-30
GB1318817A (en) 1973-05-31
NL7101407A (da) 1971-08-06
PL81653B1 (da) 1975-08-30
US3740392A (en) 1973-06-19
DE2005002A1 (da) 1971-08-12
IL36127A0 (en) 1971-04-28
BG17565A3 (da) 1973-11-10
BE762487A (fr) 1971-08-03
AT301773B (de) 1972-09-25
SE369715B (da) 1974-09-16
IL36127A (en) 1974-06-30
FI48584B (da) 1974-07-31
JPS5224016B1 (da) 1977-06-28
FI48584C (fi) 1974-11-11
IE34930B1 (en) 1975-10-01
FR2081489B1 (da) 1974-11-15
SU382281A3 (da) 1973-05-22
IE34930L (en) 1971-08-04
DK126424B (da) 1973-07-16
NO135366B (da) 1976-12-20
CH571541A5 (da) 1976-01-15
CA918635A (en) 1973-01-09
ZA71661B (en) 1971-11-24

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