ES387124A1 - Procedure for the preparation of pharmacodyamically active heterociclic aminas. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the preparation of pharmacodyamically active heterociclic aminas. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES387124A1 ES387124A1 ES387124A ES387124A ES387124A1 ES 387124 A1 ES387124 A1 ES 387124A1 ES 387124 A ES387124 A ES 387124A ES 387124 A ES387124 A ES 387124A ES 387124 A1 ES387124 A1 ES 387124A1
- Authority
- ES
- Spain
- Prior art keywords
- radical
- translation
- procedure
- preparation
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 230000001476 alcoholic effect Effects 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- -1 heterocyclic amines Chemical class 0.000 abstract 3
- 150000003254 radicals Chemical class 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical group [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 150000002081 enamines Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 238000006386 neutralization reaction Methods 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229910052711 selenium Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the preparation of pharmacodynamically active heterocyclic amines of the general formula I **(See formula)** where X means an oxygen, sulfur or selenium atom, Y means a -CH = CH- group or a sulfur atom, Z means a single bond, a -CH2- group, an oxygen atom or a divalent radical = NR4, R1 signifies a hydrogen or halogen atom, a trifluoromethyl or amino group, an alcoholic, alkoxy, alcoholylthio or alcoholic moiety elene with 1 to 4 carbon atoms, R2 and R3 signify hydrogen atoms or together they signify a divalent radical -CH2CH2-, R4 means an alcoholic or hydroxyalkyl radical with 1 to 4 carbon atoms, a cycloalkoxy or cycloalkoxy alcohol radical with 3 to 6 carbon atoms, a phenyl or benzyl radical, and their salts, characterized in that they reduce enamines of the general formula II **(See formula)** where X, Y, Z, R1, R2 and R3 mean the same as in formula I, after which the obtained basic products are transformed into corresponding salts by neutralization with organic or inorganic acids. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES387124A ES387124A1 (en) | 1971-01-09 | 1971-01-09 | Procedure for the preparation of pharmacodyamically active heterociclic aminas. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES387124A ES387124A1 (en) | 1971-01-09 | 1971-01-09 | Procedure for the preparation of pharmacodyamically active heterociclic aminas. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
Publication Number | Publication Date |
---|---|
ES387124A1 true ES387124A1 (en) | 1973-05-16 |
Family
ID=8457603
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES387124A Expired ES387124A1 (en) | 1971-01-09 | 1971-01-09 | Procedure for the preparation of pharmacodyamically active heterociclic aminas. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES387124A1 (en) |
-
1971
- 1971-01-09 ES ES387124A patent/ES387124A1/en not_active Expired
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