ES382541A1 - Procedimiento para la preparacion de esteres de metilente- traciclina. - Google Patents
Procedimiento para la preparacion de esteres de metilente- traciclina.Info
- Publication number
- ES382541A1 ES382541A1 ES382541A ES382541A ES382541A1 ES 382541 A1 ES382541 A1 ES 382541A1 ES 382541 A ES382541 A ES 382541A ES 382541 A ES382541 A ES 382541A ES 382541 A1 ES382541 A1 ES 382541A1
- Authority
- ES
- Spain
- Prior art keywords
- acid
- formula
- demethyl
- deoxy
- tetracycline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- 239000002253 acid Substances 0.000 abstract 3
- KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 abstract 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 231100000252 nontoxic Toxicity 0.000 abstract 2
- 230000003000 nontoxic effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- CCIVGXIOQKPBKL-UHFFFAOYSA-M ethanesulfonate Chemical compound CCS([O-])(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-M 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 229940098779 methanesulfonic acid Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2069969 | 1969-08-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES382541A1 true ES382541A1 (es) | 1972-12-01 |
Family
ID=11170732
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES382541A Expired ES382541A1 (es) | 1969-08-08 | 1970-08-07 | Procedimiento para la preparacion de esteres de metilente- traciclina. |
Country Status (12)
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1430859A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1960-05-23 | 1966-05-25 | ||
| US3145228A (en) * | 1962-09-06 | 1964-08-18 | Pfizer & Co C | 5-alkoxy-and 5-benzyloxy-tetracycline, derivatives and analogues thereof |
-
0
- BE BE754596D patent/BE754596A/xx unknown
-
1969
- 1969-12-19 BR BR215437/69A patent/BR6915437D0/pt unknown
-
1970
- 1970-07-27 NL NL7011074A patent/NL7011074A/xx unknown
- 1970-08-03 GB GB37360/70A patent/GB1287493A/en not_active Expired
- 1970-08-03 FR FR7028566A patent/FR2068473B1/fr not_active Expired
- 1970-08-05 NO NO3021/70A patent/NO131782C/no unknown
- 1970-08-05 CA CA089945A patent/CA931946A/en not_active Expired
- 1970-08-05 ZA ZA705429A patent/ZA705429B/xx unknown
- 1970-08-06 AT AT716470A patent/AT297931B/de not_active IP Right Cessation
- 1970-08-07 ES ES382541A patent/ES382541A1/es not_active Expired
- 1970-08-07 CH CH1195770A patent/CH539612A/de not_active IP Right Cessation
- 1970-08-07 SE SE10847/70A patent/SE360071B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH539612A (de) | 1973-07-31 |
| BE754596A (fr) | 1971-02-08 |
| NO131782C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-07-30 |
| NO131782B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-04-21 |
| FR2068473B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-08-30 |
| CA931946A (en) | 1973-08-14 |
| BR6915437D0 (pt) | 1973-01-25 |
| SE360071B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-09-17 |
| NL7011074A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1971-02-10 |
| FR2068473A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1971-08-27 |
| AT297931B (de) | 1972-04-10 |
| ZA705429B (en) | 1971-04-28 |
| GB1287493A (en) | 1972-08-31 |
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