ES380119A1 - A procedure for preparing para-chlorofenoxy-isobutirates of 3,3,5-trimethyl-cyclohexyl. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for preparing para-chlorofenoxy-isobutirates of 3,3,5-trimethyl-cyclohexyl. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES380119A1
ES380119A1 ES380119A ES380119A ES380119A1 ES 380119 A1 ES380119 A1 ES 380119A1 ES 380119 A ES380119 A ES 380119A ES 380119 A ES380119 A ES 380119A ES 380119 A1 ES380119 A1 ES 380119A1
Authority
ES
Spain
Prior art keywords
isobutirates
chlorofenoxy
trimethyl
cyclohexyl
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES380119A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES380119A1 publication Critical patent/ES380119A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/708—Ethers
    • C07C69/712—Ethers the hydroxy group of the ester being etherified with a hydroxy compound having the hydroxy group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel 3,3,5-trimethylcyclohexyl [alpha]-(p-chlorophenoxy)-isobutyrate, in the form of the cis- or trans-isomer or a mixture thereof, is prepared by reaction of a-(p-chlorophenoxy)-isobutyric acid or a functional derivative thereof with the corresponding isomer or isomer mixture of 3,3,5- trimethylcyclohexanol. Pharmaceutical compositions having hypolipaemic and peripheral vasodilatory activity comprise, as active ingredient, at least one geometrical isomer of 3,3,5-trimethylcyclohexyl [alpha]-(p-chlorophenoxy)-isobutyrate, in association with at least one pharmaceutical carrier or excipient, and may be administered buccally, rectally or transcutaneously.
ES380119A 1969-05-29 1970-05-27 A procedure for preparing para-chlorofenoxy-isobutirates of 3,3,5-trimethyl-cyclohexyl. (Machine-translation by Google Translate, not legally binding) Expired ES380119A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6917543A FR2043488A1 (en) 1969-05-29 1969-05-29

Publications (1)

Publication Number Publication Date
ES380119A1 true ES380119A1 (en) 1973-04-16

Family

ID=9034759

Family Applications (1)

Application Number Title Priority Date Filing Date
ES380119A Expired ES380119A1 (en) 1969-05-29 1970-05-27 A procedure for preparing para-chlorofenoxy-isobutirates of 3,3,5-trimethyl-cyclohexyl. (Machine-translation by Google Translate, not legally binding)

Country Status (7)

Country Link
AT (1) AT300771B (en)
BE (1) BE751089A (en)
CH (1) CH534653A (en)
DE (1) DE2026409A1 (en)
ES (1) ES380119A1 (en)
FR (1) FR2043488A1 (en)
GB (1) GB1265114A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2654429B1 (en) * 1989-11-13 1992-03-06 Panmedica Sa NOVEL 3,3,5-TRIMETHYLCYCLOHEXANOL METHYL-2-PROPIONATE DERIVATIVES, THEIR PREPARATION PROCESS AND THE THERAPEUTIC COMPOSITIONS CONTAINING THEM.
DE10332908A1 (en) 2003-07-19 2005-02-10 Symrise Gmbh & Co. Kg cis-3,3,5-trimethylcyclohexyl

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB860303A (en) * 1958-06-20 1961-02-01 Ici Ltd Pharmaceutical compositions comprising ª‡-aryloxy-aliphatic carboxylic acids and/or ª
FR1476627A (en) * 1965-12-20 1967-04-14 Bruneau & Cie Lab Cyclohexanol derivatives and their preparation

Also Published As

Publication number Publication date
GB1265114A (en) 1972-03-01
CH534653A (en) 1973-03-15
FR2043488A1 (en) 1971-02-19
DE2026409A1 (en) 1970-12-03
BE751089A (en) 1970-11-30
AT300771B (en) 1972-08-10

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