ES379188A3 - A procedure for the preparation of adamantan derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of adamantan derivatives. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES379188A3
ES379188A3 ES379188A ES379188A ES379188A3 ES 379188 A3 ES379188 A3 ES 379188A3 ES 379188 A ES379188 A ES 379188A ES 379188 A ES379188 A ES 379188A ES 379188 A3 ES379188 A3 ES 379188A3
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ES
Spain
Prior art keywords
translation
formula
derivatives
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
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ES379188A
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Spanish (es)
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E R A S M E SOC
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E R A S M E SOC
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Priority to ES379188A priority Critical patent/ES379188A3/en
Publication of ES379188A3 publication Critical patent/ES379188A3/en
Expired legal-status Critical Current

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  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A method of preparing adamantane derivatives of the general formula **(See formula)** where (see formula) can be: - a primary or secondary amine in which R1 and R2 are the same or different and are selected from hydrogen, linear or branched alkyl radicals, saturated or unsaturated, from 1 to 8 carbon atoms; When R1 and R2 are alkyl radicals, they can be linked directly or through an oxygen or nitrogen atom to form heterocyclic amines such as pyrrolidine, piperidine, hexamethyleneimine, morpholine, N-methylpiperazine, 2,2,5,5-tetramethylpyrrolidine, 2, 5-dihydro-2,2,5,5-tetramethylpyrrolidine, 2,2,6,6-tetramethylpiperidine and 1,2,3,6-tetrahydro-2,2,6,6-tetramethylpyridine; - a primary amine containing a cycloalkyl radical of 1 to 7 carbon atoms; and salts of these derivatives with organic or inorganic acids; whose procedure consists of reacting hydroxymethylammantane with epichlorohydrin, in the presence of catalytic amounts of an acid, preferably sulfuric acid; react the product obtained with an alkaline base, preferably potash, in anhydrous medium in order to form the corresponding epoxide derivative and then react this epoxide derivative with a suitable amine of the formula (see formula). (Machine-translation by Google Translate, not legally binding)
ES379188A 1970-04-29 1970-04-29 A procedure for the preparation of adamantan derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES379188A3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES379188A ES379188A3 (en) 1970-04-29 1970-04-29 A procedure for the preparation of adamantan derivatives. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES379188A ES379188A3 (en) 1970-04-29 1970-04-29 A procedure for the preparation of adamantan derivatives. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES379188A3 true ES379188A3 (en) 1972-09-01

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ID=8455777

Family Applications (1)

Application Number Title Priority Date Filing Date
ES379188A Expired ES379188A3 (en) 1970-04-29 1970-04-29 A procedure for the preparation of adamantan derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES379188A3 (en)

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