ES378315A1 - A procedure for the preparation of 1 - (omega-substituted-alcohil) -2-methylbenzimidazoles. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of 1 - (omega-substituted-alcohil) -2-methylbenzimidazoles. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES378315A1 ES378315A1 ES378315A ES378315A ES378315A1 ES 378315 A1 ES378315 A1 ES 378315A1 ES 378315 A ES378315 A ES 378315A ES 378315 A ES378315 A ES 378315A ES 378315 A1 ES378315 A1 ES 378315A1
- Authority
- ES
- Spain
- Prior art keywords
- phenyl
- omega
- methylbenzimidazoles
- translation
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Abstract
A process for the preparation of 1- (omega-substituted-alkyl) -2-methylbenzimidazoles having the formula: ** (see formula) ** Wherein: sub is selected from the group of heterocyclic radicals consisting of 4-phenylpiperazinyl, 4-phenyl-piperidinyl, 4-phenyl-1,2,3,6-tetrahydropyridinyl, 4-phenyl-4-hydroxypiperidinyl, 3-phenyl- 3-hydroxypyrrolidinyl, 3- (N-methylanilino) pyrrolidinyl, 3-phenylpyrrolidinyl and 3-phenyl-3-pyrrolinyl, wherein phenyl is the unsubstituted phenyl radical and the monosubstituted phenyl radical, and the monosubstituent is selected from the group consisting of lower alkyl, lower alkoxy, trifluoromethyl and halogen of atomic weight less than 80; n is a positive integer of two to three inclusive; characterized in that it comprises the steps of: alkylating a 2-methylbenzimidazole with an omega halogenoalcohol, halogenating the 1- (omega-hydroxyalcohyl) -2-methylbenzimidazole obtained above, and reacting the 1- (omega-halogenoalcohyl) -2-methyl-benzimidazole thus prepared with a nitrogen-containing five- to six-membered heterocyclic compound having the sub formula defined above. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81549269A | 1969-04-11 | 1969-04-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES378315A1 true ES378315A1 (en) | 1972-06-01 |
Family
ID=25217960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES378315A Expired ES378315A1 (en) | 1969-04-11 | 1970-04-07 | A procedure for the preparation of 1 - (omega-substituted-alcohil) -2-methylbenzimidazoles. (Machine-translation by Google Translate, not legally binding) |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JPS4837275B1 (en) |
| ES (1) | ES378315A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2723091B1 (en) * | 1994-07-29 | 1996-11-08 | Esteve Labor Dr | TETRAHYDROPYRIDINE- (6,4-HYDROXYPIPERIDINE) ALKYLAZOLES |
-
1970
- 1970-04-07 ES ES378315A patent/ES378315A1/en not_active Expired
- 1970-04-11 JP JP3069870A patent/JPS4837275B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPS4837275B1 (en) | 1973-11-09 |
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