ES378296A1 - Procedimiento para resolver en los antipodas opticos deri- vados racemicos de 3-succioniloxi-5-fenil-1,3-dihidro-2h-1,4-benzodiacepin-2-ona. - Google Patents
Procedimiento para resolver en los antipodas opticos deri- vados racemicos de 3-succioniloxi-5-fenil-1,3-dihidro-2h-1,4-benzodiacepin-2-ona.Info
- Publication number
- ES378296A1 ES378296A1 ES378296A ES378296A ES378296A1 ES 378296 A1 ES378296 A1 ES 378296A1 ES 378296 A ES378296 A ES 378296A ES 378296 A ES378296 A ES 378296A ES 378296 A1 ES378296 A1 ES 378296A1
- Authority
- ES
- Spain
- Prior art keywords
- succinyloxy
- benzodiazepine
- dihydro
- phenyl
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229940049706 benzodiazepine Drugs 0.000 title 1
- 230000003287 optical effect Effects 0.000 title 1
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- KWGRBVOPPLSCSI-WPRPVWTQSA-N (-)-ephedrine Chemical compound CN[C@@H](C)[C@H](O)C1=CC=CC=C1 KWGRBVOPPLSCSI-WPRPVWTQSA-N 0.000 abstract 2
- KWGRBVOPPLSCSI-UHFFFAOYSA-N d-ephedrine Natural products CNC(C)C(O)C1=CC=CC=C1 KWGRBVOPPLSCSI-UHFFFAOYSA-N 0.000 abstract 1
- 229960002179 ephedrine Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000007928 solubilization Effects 0.000 abstract 1
- 238000005063 solubilization Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
- C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB975970A GB1268783A (en) | 1969-04-08 | 1969-04-08 | Benzodiazepine derivatives |
| GB1803469 | 1969-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES378296A1 true ES378296A1 (es) | 1973-02-01 |
Family
ID=26243153
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES378296A Expired ES378296A1 (es) | 1969-04-08 | 1970-04-06 | Procedimiento para resolver en los antipodas opticos deri- vados racemicos de 3-succioniloxi-5-fenil-1,3-dihidro-2h-1,4-benzodiacepin-2-ona. |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US3654267A (cg-RX-API-DMAC7.html) |
| BE (1) | BE791988Q (cg-RX-API-DMAC7.html) |
| CH (1) | CH533067A (cg-RX-API-DMAC7.html) |
| DE (1) | DE2016810A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES378296A1 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2068453B1 (cg-RX-API-DMAC7.html) |
| NL (1) | NL7004846A (cg-RX-API-DMAC7.html) |
| NO (1) | NO123760B (cg-RX-API-DMAC7.html) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1292474A (en) * | 1970-06-25 | 1972-10-11 | Ravizza Spa | Benzodiazepine derivatives |
| US3903276A (en) * | 1972-03-20 | 1975-09-02 | American Home Prod | N-carboxymethyl-N-substituted glycinate esters of 3-hydroxy-1,4-benzodiazepin-2-ones for inducing a calming effect |
-
0
- BE BE791988D patent/BE791988Q/xx active
-
1970
- 1970-03-25 US US22673A patent/US3654267A/en not_active Expired - Lifetime
- 1970-04-03 NL NL7004846A patent/NL7004846A/xx unknown
- 1970-04-06 ES ES378296A patent/ES378296A1/es not_active Expired
- 1970-04-07 NO NO1275/70A patent/NO123760B/no unknown
- 1970-04-08 CH CH519670A patent/CH533067A/de not_active IP Right Cessation
- 1970-04-08 FR FR7012692A patent/FR2068453B1/fr not_active Expired
- 1970-04-08 DE DE19702016810 patent/DE2016810A1/de active Pending
-
1972
- 1972-09-11 US US28773472 patent/USRE28287E/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US3654267A (en) | 1972-04-04 |
| NO123760B (cg-RX-API-DMAC7.html) | 1972-01-10 |
| DE2016810A1 (de) | 1970-11-19 |
| FR2068453B1 (cg-RX-API-DMAC7.html) | 1974-05-24 |
| CH533067A (de) | 1973-01-31 |
| FR2068453A1 (cg-RX-API-DMAC7.html) | 1971-08-27 |
| NL7004846A (cg-RX-API-DMAC7.html) | 1970-10-12 |
| USRE28287E (en) | 1974-12-31 |
| BE791988Q (fr) | 1973-03-16 |
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