ES377228A1 - Procedimiento para la preparacion de una 7-aminocefalosporina. - Google Patents
Procedimiento para la preparacion de una 7-aminocefalosporina.Info
- Publication number
- ES377228A1 ES377228A1 ES377228A ES377228A ES377228A1 ES 377228 A1 ES377228 A1 ES 377228A1 ES 377228 A ES377228 A ES 377228A ES 377228 A ES377228 A ES 377228A ES 377228 A1 ES377228 A1 ES 377228A1
- Authority
- ES
- Spain
- Prior art keywords
- acid
- methyl
- hydrogen
- solvent
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title 1
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 229930186147 Cephalosporin Natural products 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 3
- 229940124587 cephalosporin Drugs 0.000 abstract 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 2
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 239000006184 cosolvent Substances 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- HRDXJKGNWSUIBT-UHFFFAOYSA-N methoxybenzene Chemical group [CH2]OC1=CC=CC=C1 HRDXJKGNWSUIBT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- -1 nitro, hydroxy Chemical group 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 239000001117 sulphuric acid Substances 0.000 abstract 1
- 235000011149 sulphuric acid Nutrition 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80582369A | 1969-03-10 | 1969-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES377228A1 true ES377228A1 (es) | 1972-06-01 |
Family
ID=25192601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES377228A Expired ES377228A1 (es) | 1969-03-10 | 1970-03-06 | Procedimiento para la preparacion de una 7-aminocefalosporina. |
Country Status (13)
-
1970
- 1970-02-06 CA CA074,173A patent/CA974516A/en not_active Expired
- 1970-02-10 IE IE176/70A patent/IE33722B1/xx unknown
- 1970-02-12 IL IL33889A patent/IL33889A/en unknown
- 1970-03-03 NL NL7003048A patent/NL7003048A/xx unknown
- 1970-03-05 BE BE746860D patent/BE746860A/xx unknown
- 1970-03-06 DE DE19702010757 patent/DE2010757A1/de active Pending
- 1970-03-06 ES ES377228A patent/ES377228A1/es not_active Expired
- 1970-03-09 SE SE7003123A patent/SE374374B/xx unknown
- 1970-03-10 CH CH351170A patent/CH529788A/de not_active IP Right Cessation
- 1970-03-10 FR FR7008534A patent/FR2037887A5/fr not_active Expired
- 1970-03-10 GB GB1266252D patent/GB1266252A/en not_active Expired
- 1970-03-10 AT AT224670A patent/AT293620B/de not_active IP Right Cessation
- 1970-03-10 JP JP45019797A patent/JPS4931999B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL33889A (en) | 1973-04-30 |
| FR2037887A5 (fr) | 1970-12-31 |
| NL7003048A (enrdf_load_stackoverflow) | 1970-09-14 |
| JPS4931999B1 (enrdf_load_stackoverflow) | 1974-08-27 |
| BE746860A (fr) | 1970-09-07 |
| IE33722L (en) | 1970-09-10 |
| SE374374B (enrdf_load_stackoverflow) | 1975-03-03 |
| IE33722B1 (en) | 1974-10-02 |
| IL33889A0 (en) | 1970-04-20 |
| AT293620B (de) | 1971-10-25 |
| CH529788A (de) | 1972-10-31 |
| GB1266252A (enrdf_load_stackoverflow) | 1972-03-08 |
| CA974516A (en) | 1975-09-16 |
| DE2010757A1 (de) | 1970-09-17 |
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