ES371331A1 - Procedimiento para la preparacion de derivados de 14 alfa, 17 alfa-metilendioxi-19-nor-progesterona. - Google Patents
Procedimiento para la preparacion de derivados de 14 alfa, 17 alfa-metilendioxi-19-nor-progesterona.Info
- Publication number
- ES371331A1 ES371331A1 ES371331A ES371331A ES371331A1 ES 371331 A1 ES371331 A1 ES 371331A1 ES 371331 A ES371331 A ES 371331A ES 371331 A ES371331 A ES 371331A ES 371331 A1 ES371331 A1 ES 371331A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- derivative
- general formula
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001440 androstane derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical group 0.000 abstract 6
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000000318 19-norprogesterones Chemical class 0.000 abstract 1
- -1 20,20-ethylenedioxy Chemical class 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB43295/68A GB1277886A (en) | 1968-09-11 | 1968-09-11 | Androstenones |
Publications (1)
Publication Number | Publication Date |
---|---|
ES371331A1 true ES371331A1 (es) | 1971-10-16 |
Family
ID=10428135
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES371331A Expired ES371331A1 (es) | 1968-09-11 | 1969-09-09 | Procedimiento para la preparacion de derivados de 14 alfa, 17 alfa-metilendioxi-19-nor-progesterona. |
ES371330A Expired ES371330A1 (es) | 1968-09-11 | 1969-09-09 | Procedimiento para la preparacion de derivados de 14 alta, 17 alfa-metilendioxi-androstano. |
ES371332A Expired ES371332A1 (es) | 1968-09-11 | 1969-09-09 | Procedimiento para la preparacion de derivados de 14 alfa, 17 alfa-metilendioxiestrano. |
ES381473A Expired ES381473A1 (es) | 1968-09-11 | 1970-07-06 | Procedimiento para la preparacion de 17 beta-halo-14 alfa,-17 alfa-metailendioxi-estrano. |
Family Applications After (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES371330A Expired ES371330A1 (es) | 1968-09-11 | 1969-09-09 | Procedimiento para la preparacion de derivados de 14 alta, 17 alfa-metilendioxi-androstano. |
ES371332A Expired ES371332A1 (es) | 1968-09-11 | 1969-09-09 | Procedimiento para la preparacion de derivados de 14 alfa, 17 alfa-metilendioxiestrano. |
ES381473A Expired ES381473A1 (es) | 1968-09-11 | 1970-07-06 | Procedimiento para la preparacion de 17 beta-halo-14 alfa,-17 alfa-metailendioxi-estrano. |
Country Status (13)
Country | Link |
---|---|
US (1) | US3585191A (es) |
BE (3) | BE738667A (es) |
BR (3) | BR6912307D0 (es) |
CA (1) | CA958004A (es) |
DE (3) | DE1945879A1 (es) |
DK (1) | DK127554B (es) |
ES (4) | ES371331A1 (es) |
FR (3) | FR2017797A1 (es) |
GB (1) | GB1277886A (es) |
IE (1) | IE33607B1 (es) |
IL (3) | IL32935A (es) |
NL (2) | NL6913815A (es) |
SE (1) | SE355361B (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3905962A (en) * | 1970-03-06 | 1975-09-16 | Arthur Friedrich Marx | Oestratrienes |
DE2748442C3 (de) * | 1977-10-26 | 1981-08-27 | Schering Ag Berlin Und Bergkamen, 1000 Berlin | 17α-(3-Jodbenzoyloxy)-9α -chlor4-pregnen-3.20-dione, Zwischenprodukte und Verfahren zu ihrer Herstellung, 9α -chlor-17α, 21-dihydroxy-1,4-pregnadien-3,20-dion und dieses enthaltende Arzneimittel |
EP0188010A1 (en) * | 1985-01-14 | 1986-07-23 | Gist-Brocades N.V. | New process for the preparation of certain steroids, especially intermediates for the preparation of proligestone and related compounds, and new intermediates formed in this process |
-
1968
- 1968-09-11 GB GB43295/68A patent/GB1277886A/en not_active Expired
-
1969
- 1969-09-03 IL IL32935A patent/IL32935A/en unknown
- 1969-09-03 IL IL32936A patent/IL32936A0/xx unknown
- 1969-09-03 IL IL32937A patent/IL32937A0/xx unknown
- 1969-09-08 SE SE12361/69A patent/SE355361B/xx unknown
- 1969-09-09 US US856467A patent/US3585191A/en not_active Expired - Lifetime
- 1969-09-09 ES ES371331A patent/ES371331A1/es not_active Expired
- 1969-09-09 IE IE1267/69A patent/IE33607B1/xx unknown
- 1969-09-09 ES ES371330A patent/ES371330A1/es not_active Expired
- 1969-09-09 ES ES371332A patent/ES371332A1/es not_active Expired
- 1969-09-10 DE DE19691945879 patent/DE1945879A1/de active Pending
- 1969-09-10 FR FR6930802A patent/FR2017797A1/fr not_active Withdrawn
- 1969-09-10 BE BE738667D patent/BE738667A/xx unknown
- 1969-09-10 BE BE738666D patent/BE738666A/xx unknown
- 1969-09-10 BR BR212307/69A patent/BR6912307D0/pt unknown
- 1969-09-10 FR FR696930801A patent/FR2017796B1/fr not_active Expired
- 1969-09-10 BR BR212308/69A patent/BR6912308D0/pt unknown
- 1969-09-10 FR FR6930803A patent/FR2017798A1/fr not_active Withdrawn
- 1969-09-10 DK DK484569AA patent/DK127554B/da unknown
- 1969-09-10 BR BR212309/69A patent/BR6912309D0/pt unknown
- 1969-09-10 DE DE19691945877 patent/DE1945877A1/de active Pending
- 1969-09-10 DE DE19691945878 patent/DE1945878A1/de active Pending
- 1969-09-10 BE BE738668D patent/BE738668A/xx unknown
- 1969-09-11 CA CA061,769A patent/CA958004A/en not_active Expired
- 1969-09-11 NL NL6913815A patent/NL6913815A/xx unknown
- 1969-09-11 NL NL6913816A patent/NL6913816A/xx unknown
-
1970
- 1970-07-06 ES ES381473A patent/ES381473A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR2017796A1 (es) | 1970-05-22 |
BE738667A (es) | 1970-03-10 |
BR6912309D0 (pt) | 1973-03-13 |
CA958004A (en) | 1974-11-19 |
FR2017797A1 (es) | 1970-05-22 |
SE355361B (es) | 1973-04-16 |
ES371332A1 (es) | 1971-10-16 |
BE738668A (es) | 1970-03-10 |
IE33607L (en) | 1970-03-11 |
FR2017796B1 (es) | 1973-07-13 |
DK127554B (da) | 1973-11-26 |
BR6912308D0 (pt) | 1973-04-12 |
IE33607B1 (en) | 1974-09-04 |
FR2017798A1 (es) | 1970-05-22 |
IL32937A0 (en) | 1969-11-30 |
US3585191A (en) | 1971-06-15 |
NL6913816A (es) | 1970-03-13 |
IL32935A (en) | 1973-08-29 |
DE1945877A1 (de) | 1970-07-23 |
ES371330A1 (es) | 1971-10-16 |
DE1945879A1 (de) | 1970-03-19 |
IL32935A0 (en) | 1969-11-30 |
BR6912307D0 (pt) | 1973-05-10 |
ES381473A1 (es) | 1972-11-16 |
IL32936A0 (en) | 1969-11-30 |
BE738666A (es) | 1970-03-10 |
DE1945878A1 (de) | 1970-03-19 |
NL6913815A (es) | 1970-03-13 |
GB1277886A (en) | 1972-06-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES324500A1 (es) | Procedimiento para la preparacion de composiciones herbicidas. | |
ES371331A1 (es) | Procedimiento para la preparacion de derivados de 14 alfa, 17 alfa-metilendioxi-19-nor-progesterona. | |
ES389912A1 (es) | Un procedimiento para la preparacion de compuestos odoran- tes. | |
ES390952A1 (es) | Procedimiento para la preparacion de 2-piperidilcarbinoles. | |
ES429020A1 (es) | Procedimiento para preparar nuevos derivados de tiazol-5- metanol. | |
ES372576A1 (es) | Procedimiento para la obtencion de derivados del acido ace-tico bis-(fenoxisustituidos). | |
ES395495A1 (es) | Procedimiento para la obtencion de derivados de indol. | |
ES378236A1 (es) | Procedimiento para la preparacion de nuevas 3 - (5-nitro-2-imidazolilmetilenamino)-2-oxazolidinonas. | |
ES334935A1 (es) | Procedimiento de isomerizacion para la preparacion de gone-nos sinteticos. | |
ES405438A1 (es) | Procedimiento para la preparacion de nuevos 2-acil-nitro- tiazoles. | |
ES312151A1 (es) | Un metodo de preparar nuevos indoliletilguanidinas. | |
ES399726A1 (es) | Procedimiento para la preparacion de compuestos para ali- viar sintomas de la enfermedad de parkinson. | |
GR37786B (el) | Μεθοδος δια την παρασκευην νεων υποκατεστημενων ενωσεων βενζυλοπυριδινιου. | |
ES416480A1 (es) | Procedimiento para la obtencion de derivados del benzocic- loheptatiofeno. | |
ES399820A1 (es) | Procedimiento para la obtencion de derivados de amino pro- panol. | |
ES418711A1 (es) | Procedimiento para la obtencion de esteroides 11-metil-17 prepadienil sustituidos. | |
ES335109A1 (es) | Mejoras introducidas en la preparacion de composiciones farmaceuticas que comprenden un ester. | |
ES387238A1 (es) | Un procedimiento para la preparacion de nuevos compuestos odorantes. | |
ES307439A1 (es) | Procedimiento para la obtencion de un esteroide de alta eficacia ostrogenica. | |
GB1251028A (es) | ||
ES307440A1 (es) | Procedimiento para la obtencion de un esteroide de efecto ostrogenico. | |
ES383319A1 (es) | Un procedimiento para la preparacion de derivados esteroi- dales terapeuticamente importantes y nuevos compuestos in- termedios utiles en este procedimiento. | |
ES331674A1 (es) | Procedimiento para la obtencion de derivados de la benzodiacepin-2-ona. | |
ES387315A1 (es) | Procedimiento para la obtencion de 17-monoesteres de este- roides dihidroxilados en c17 y c21. | |
ES380388A1 (es) | Procedimiento para la preparacion de 5 - nitro-2-furfurili-den-amino - oxazolidinonas. |