CA958004A - 19-nor-progesterone derivatives - Google Patents

19-nor-progesterone derivatives

Info

Publication number
CA958004A
CA958004A CA061,769A CA61769A CA958004A CA 958004 A CA958004 A CA 958004A CA 61769 A CA61769 A CA 61769A CA 958004 A CA958004 A CA 958004A
Authority
CA
Canada
Prior art keywords
progesterone derivatives
progesterone
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA061,769A
Other languages
English (en)
Inventor
Arthur F. Marx
Hermanus J. Kooreman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Delft BV
Original Assignee
Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Nederlandsche Gist en Spiritusfabriek BV filed Critical Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Application granted granted Critical
Publication of CA958004A publication Critical patent/CA958004A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA061,769A 1968-09-11 1969-09-11 19-nor-progesterone derivatives Expired CA958004A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB43295/68A GB1277886A (en) 1968-09-11 1968-09-11 Androstenones

Publications (1)

Publication Number Publication Date
CA958004A true CA958004A (en) 1974-11-19

Family

ID=10428135

Family Applications (1)

Application Number Title Priority Date Filing Date
CA061,769A Expired CA958004A (en) 1968-09-11 1969-09-11 19-nor-progesterone derivatives

Country Status (13)

Country Link
US (1) US3585191A (es)
BE (3) BE738667A (es)
BR (3) BR6912309D0 (es)
CA (1) CA958004A (es)
DE (3) DE1945879A1 (es)
DK (1) DK127554B (es)
ES (4) ES371332A1 (es)
FR (3) FR2017798A1 (es)
GB (1) GB1277886A (es)
IE (1) IE33607B1 (es)
IL (3) IL32937A0 (es)
NL (2) NL6913815A (es)
SE (1) SE355361B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905962A (en) * 1970-03-06 1975-09-16 Arthur Friedrich Marx Oestratrienes
DE2748442C3 (de) * 1977-10-26 1981-08-27 Schering Ag Berlin Und Bergkamen, 1000 Berlin 17α-(3-Jodbenzoyloxy)-9α -chlor4-pregnen-3.20-dione, Zwischenprodukte und Verfahren zu ihrer Herstellung, 9α -chlor-17α, 21-dihydroxy-1,4-pregnadien-3,20-dion und dieses enthaltende Arzneimittel
EP0188010A1 (en) * 1985-01-14 1986-07-23 Gist-Brocades N.V. New process for the preparation of certain steroids, especially intermediates for the preparation of proligestone and related compounds, and new intermediates formed in this process

Also Published As

Publication number Publication date
DE1945878A1 (de) 1970-03-19
BR6912308D0 (pt) 1973-04-12
US3585191A (en) 1971-06-15
IL32935A (en) 1973-08-29
BR6912307D0 (pt) 1973-05-10
FR2017796A1 (es) 1970-05-22
NL6913815A (es) 1970-03-13
IL32937A0 (en) 1969-11-30
FR2017796B1 (es) 1973-07-13
SE355361B (es) 1973-04-16
BE738666A (es) 1970-03-10
ES371331A1 (es) 1971-10-16
BR6912309D0 (pt) 1973-03-13
NL6913816A (es) 1970-03-13
IE33607B1 (en) 1974-09-04
IL32935A0 (en) 1969-11-30
GB1277886A (en) 1972-06-14
ES371332A1 (es) 1971-10-16
DE1945877A1 (de) 1970-07-23
ES381473A1 (es) 1972-11-16
IL32936A0 (en) 1969-11-30
BE738668A (es) 1970-03-10
DK127554B (da) 1973-11-26
FR2017798A1 (es) 1970-05-22
DE1945879A1 (de) 1970-03-19
IE33607L (en) 1970-03-11
FR2017797A1 (es) 1970-05-22
BE738667A (es) 1970-03-10
ES371330A1 (es) 1971-10-16

Similar Documents

Publication Publication Date Title
CA954512A (en) 5-phenyl-tetrazole derivatives
AU502845B2 (en) Eburnamenine derivatives
CA956312A (en) Quinuclidin-quinolinemethanol derivatives
CA958004A (en) 19-nor-progesterone derivatives
CA781467A (en) Furochromone derivatives
CA944354A (en) Cycloalkano-quinolone derivatives
CA795330A (en) Dibenzocycloheptadiene-5-carboxamide derivatives
CA957382A (en) Azetidinol derivatives
CA945548A (en) 2-iminobenzodiazepine derivatives
CA795792A (en) Benzamidobenzanilide derivatives
CA796733A (en) Gonatriene derivatives
AU426865B2 (en) Benaodiazepine derivatives
AU429548B2 (en) Diaryloxalamide derivatives
AU429809B2 (en) 5-nitrofuran derivatives
AU431609B2 (en) Cycloalkano-quinolone derivatives
AU435189B2 (en) Phthaloyl-benzopyrrocoline derivatives
CA802903A (en) 1-aza-thiaxanthene derivatives
CA801742A (en) Benzothiadiazinedioxide derivatives
CA801054A (en) 3-hydroxyisoxazole derivatives
CA801013A (en) 16-alkyl-progesterone derivatives
CA799484A (en) Triphenylhaloethylene derivatives
AU442136B2 (en) Benzothiopyranopyridine derivatives
AU441802B2 (en) Indenopyridine derivatives
CA781930A (en) Bromopyridazone derivatives
CA784232A (en) Thiaxanthene-1-oxide derivatives