DK127554B - Analogifremgangsmåde til fremstilling af 14α 17α-methylendioxy-19-nor-progesteronderivater. - Google Patents

Analogifremgangsmåde til fremstilling af 14α 17α-methylendioxy-19-nor-progesteronderivater.

Info

Publication number
DK127554B
DK127554B DK484569AA DK484569A DK127554B DK 127554 B DK127554 B DK 127554B DK 484569A A DK484569A A DK 484569AA DK 484569 A DK484569 A DK 484569A DK 127554 B DK127554 B DK 127554B
Authority
DK
Denmark
Prior art keywords
methylenedioxy
preparation
analogous process
progesterone derivatives
progesterone
Prior art date
Application number
DK484569AA
Other languages
English (en)
Inventor
A Marx
H Kooreman
Original Assignee
Koninklijke Gist Spiritus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Gist Spiritus filed Critical Koninklijke Gist Spiritus
Priority to DK381171A priority Critical patent/DK129343B/da
Publication of DK127554B publication Critical patent/DK127554B/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005Ketals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J71/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005Oxygen-containing hetero ring
    • C07J71/0026Oxygen-containing hetero ring cyclic ketals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK484569AA 1968-09-11 1969-09-10 Analogifremgangsmåde til fremstilling af 14α 17α-methylendioxy-19-nor-progesteronderivater. DK127554B (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK381171A DK129343B (da) 1968-09-11 1971-08-04 14α,17α-methylendioxy-pregnanderivater til anvendelse i kontraceptive midler.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB43295/68A GB1277886A (en) 1968-09-11 1968-09-11 Androstenones

Publications (1)

Publication Number Publication Date
DK127554B true DK127554B (da) 1973-11-26

Family

ID=10428135

Family Applications (1)

Application Number Title Priority Date Filing Date
DK484569AA DK127554B (da) 1968-09-11 1969-09-10 Analogifremgangsmåde til fremstilling af 14α 17α-methylendioxy-19-nor-progesteronderivater.

Country Status (13)

Country Link
US (1) US3585191A (da)
BE (3) BE738666A (da)
BR (3) BR6912308D0 (da)
CA (1) CA958004A (da)
DE (3) DE1945877A1 (da)
DK (1) DK127554B (da)
ES (4) ES371331A1 (da)
FR (3) FR2017798A1 (da)
GB (1) GB1277886A (da)
IE (1) IE33607B1 (da)
IL (3) IL32936A0 (da)
NL (2) NL6913815A (da)
SE (1) SE355361B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3905962A (en) * 1970-03-06 1975-09-16 Arthur Friedrich Marx Oestratrienes
DE2748442C3 (de) * 1977-10-26 1981-08-27 Schering Ag Berlin Und Bergkamen, 1000 Berlin 17α-(3-Jodbenzoyloxy)-9α -chlor4-pregnen-3.20-dione, Zwischenprodukte und Verfahren zu ihrer Herstellung, 9α -chlor-17α, 21-dihydroxy-1,4-pregnadien-3,20-dion und dieses enthaltende Arzneimittel
EP0188010A1 (en) * 1985-01-14 1986-07-23 Gist-Brocades N.V. New process for the preparation of certain steroids, especially intermediates for the preparation of proligestone and related compounds, and new intermediates formed in this process

Also Published As

Publication number Publication date
FR2017796A1 (da) 1970-05-22
IL32936A0 (en) 1969-11-30
ES371331A1 (es) 1971-10-16
DE1945879A1 (de) 1970-03-19
DE1945878A1 (de) 1970-03-19
FR2017798A1 (da) 1970-05-22
NL6913816A (da) 1970-03-13
SE355361B (da) 1973-04-16
IE33607B1 (en) 1974-09-04
FR2017796B1 (da) 1973-07-13
BR6912308D0 (pt) 1973-04-12
BE738668A (da) 1970-03-10
BE738667A (da) 1970-03-10
IL32935A0 (en) 1969-11-30
CA958004A (en) 1974-11-19
IL32937A0 (en) 1969-11-30
ES381473A1 (es) 1972-11-16
DE1945877A1 (de) 1970-07-23
ES371330A1 (es) 1971-10-16
US3585191A (en) 1971-06-15
NL6913815A (da) 1970-03-13
FR2017797A1 (da) 1970-05-22
BE738666A (da) 1970-03-10
IE33607L (en) 1970-03-11
ES371332A1 (es) 1971-10-16
GB1277886A (en) 1972-06-14
BR6912307D0 (pt) 1973-05-10
IL32935A (en) 1973-08-29
BR6912309D0 (pt) 1973-03-13

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