ES370718A1 - Un metodo de preparacion de una 5-amino sustituido-6-cloro-1h - imidazo (4,5-b) pirazin-2-ona. - Google Patents
Un metodo de preparacion de una 5-amino sustituido-6-cloro-1h - imidazo (4,5-b) pirazin-2-ona.Info
- Publication number
- ES370718A1 ES370718A1 ES370718A ES370718A ES370718A1 ES 370718 A1 ES370718 A1 ES 370718A1 ES 370718 A ES370718 A ES 370718A ES 370718 A ES370718 A ES 370718A ES 370718 A1 ES370718 A1 ES 370718A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- group
- imidazo
- hydrogen atom
- optionally
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- KYQCOXFCLRTKLS-UHFFFAOYSA-N Pyrazine Chemical compound C1=CN=CC=N1 KYQCOXFCLRTKLS-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- -1 acetamidomethyl Chemical group 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- HUTNOYOBQPAKIA-UHFFFAOYSA-N 1h-pyrazin-2-one Chemical compound OC1=CN=CC=N1 HUTNOYOBQPAKIA-UHFFFAOYSA-N 0.000 abstract 1
- 125000002373 5 membered heterocyclic group Chemical group 0.000 abstract 1
- 125000004070 6 membered heterocyclic group Chemical group 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000002934 diuretic Substances 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000001841 imino group Chemical class [H]N=* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical class O* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000008024 pharmaceutical diluent Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 230000000894 saliuretic effect Effects 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA28998 | 1968-08-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES370718A1 true ES370718A1 (es) | 1971-10-16 |
Family
ID=4084476
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES370718A Expired ES370718A1 (es) | 1968-08-31 | 1969-08-21 | Un metodo de preparacion de una 5-amino sustituido-6-cloro-1h - imidazo (4,5-b) pirazin-2-ona. |
Country Status (5)
| Country | Link |
|---|---|
| AT (1) | AT292712B (enrdf_load_stackoverflow) |
| BR (1) | BR6911905D0 (enrdf_load_stackoverflow) |
| ES (1) | ES370718A1 (enrdf_load_stackoverflow) |
| GB (1) | GB1248146A (enrdf_load_stackoverflow) |
| NL (1) | NL6911868A (enrdf_load_stackoverflow) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2368843A (en) * | 2000-11-08 | 2002-05-15 | Leuven K U Res & Dev | Non-porphyrin multipurpose contrast agents |
| UY32799A (es) | 2009-07-24 | 2011-02-28 | Novartis Ag | Derivados de oxazina y su uso en el tratamiento de trastornos neurológicos |
| EA201200952A1 (ru) | 2009-12-31 | 2013-02-28 | Новартис Аг | Производные пиразина и их применение для лечения неврологических нарушений |
| BR112013017779A2 (pt) | 2011-01-12 | 2016-10-11 | Novartis Ag | derivados de oxazina e seu uso no tratamento de distúrbios neurológicos |
| DK2663561T3 (en) | 2011-01-13 | 2016-06-06 | Novartis Ag | New heterocyclic derivatives and their use in treating neurological disorders |
| UY34278A (es) | 2011-08-25 | 2013-04-05 | Novartis Ag | Derivados novedosos de oxazina y su uso en el tratamiento de enfermedades |
-
1969
- 1969-08-04 NL NL6911868A patent/NL6911868A/xx unknown
- 1969-08-21 ES ES370718A patent/ES370718A1/es not_active Expired
- 1969-08-25 GB GB4218569A patent/GB1248146A/en not_active Expired
- 1969-08-27 BR BR21190569A patent/BR6911905D0/pt unknown
- 1969-08-29 AT AT830069A patent/AT292712B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AT292712B (de) | 1971-09-10 |
| NL6911868A (enrdf_load_stackoverflow) | 1970-03-03 |
| GB1248146A (en) | 1971-09-29 |
| BR6911905D0 (pt) | 1973-04-26 |
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