ES367108A1 - Un procedimiento para la preparacion de acido (cis-1,2-epo-xipropil) fosfonico y derivados del mismo - Google Patents
Un procedimiento para la preparacion de acido (cis-1,2-epo-xipropil) fosfonico y derivados del mismoInfo
- Publication number
- ES367108A1 ES367108A1 ES367108A ES367108A ES367108A1 ES 367108 A1 ES367108 A1 ES 367108A1 ES 367108 A ES367108 A ES 367108A ES 367108 A ES367108 A ES 367108A ES 367108 A1 ES367108 A1 ES 367108A1
- Authority
- ES
- Spain
- Prior art keywords
- cis
- phosphonic acid
- compound
- salts
- mixture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 abstract 7
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 6
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 6
- 239000000203 mixture Substances 0.000 abstract 6
- -1 organic base salts Chemical class 0.000 abstract 5
- 150000001875 compounds Chemical class 0.000 abstract 4
- XWCIXXXLOAAWPU-IHWYPQMZSA-N [(z)-prop-1-enyl]phosphonic acid Chemical compound C\C=C/P(O)(O)=O XWCIXXXLOAAWPU-IHWYPQMZSA-N 0.000 abstract 3
- 239000002585 base Substances 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 229910052751 metal Inorganic materials 0.000 abstract 3
- 239000002184 metal Substances 0.000 abstract 3
- 239000007858 starting material Substances 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- VQTUBCCKSQIDNK-UHFFFAOYSA-N Isobutene Chemical compound CC(C)=C VQTUBCCKSQIDNK-UHFFFAOYSA-N 0.000 abstract 2
- DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 abstract 2
- 239000007822 coupling agent Substances 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 238000010438 heat treatment Methods 0.000 abstract 2
- 229910052749 magnesium Inorganic materials 0.000 abstract 2
- 150000002739 metals Chemical class 0.000 abstract 2
- 238000010992 reflux Methods 0.000 abstract 2
- 229910052708 sodium Inorganic materials 0.000 abstract 2
- LLYOWLBKUFLSKB-UHFFFAOYSA-N (3-tert-butyl-4,4-dimethylpent-1-yn-3-yl) dihydrogen phosphite Chemical compound CC(C)(C)C(C#C)(C(C)(C)C)OP(O)O LLYOWLBKUFLSKB-UHFFFAOYSA-N 0.000 abstract 1
- DYLIWHYUXAJDOJ-OWOJBTEDSA-N (e)-4-(6-aminopurin-9-yl)but-2-en-1-ol Chemical compound NC1=NC=NC2=C1N=CN2C\C=C\CO DYLIWHYUXAJDOJ-OWOJBTEDSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 239000004411 aluminium Substances 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- NNLQAVXYYOHHBT-UHFFFAOYSA-N chloro-bis[(2-methylpropan-2-yl)oxy]phosphane Chemical compound CC(C)(C)OP(Cl)OC(C)(C)C NNLQAVXYYOHHBT-UHFFFAOYSA-N 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000001640 fractional crystallisation Methods 0.000 abstract 1
- 150000008282 halocarbons Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229910001507 metal halide Inorganic materials 0.000 abstract 1
- 150000005309 metal halides Chemical class 0.000 abstract 1
- 239000007769 metal material Substances 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- WURFKUQACINBSI-UHFFFAOYSA-M ozonide Chemical compound [O]O[O-] WURFKUQACINBSI-UHFFFAOYSA-M 0.000 abstract 1
- 230000000737 periodic effect Effects 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-M phenolate Chemical compound [O-]C1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-M 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- XWCIXXXLOAAWPU-UHFFFAOYSA-N prop-1-enylphosphonic acid Chemical compound CC=CP(O)(O)=O XWCIXXXLOAAWPU-UHFFFAOYSA-N 0.000 abstract 1
- TVDSBUOJIPERQY-UHFFFAOYSA-N prop-2-yn-1-ol Chemical compound OCC#C TVDSBUOJIPERQY-UHFFFAOYSA-N 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
- 229910052709 silver Inorganic materials 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 229910052725 zinc Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D323/00—Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
- C07D323/04—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
- C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72942368A | 1968-05-15 | 1968-05-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES367108A1 true ES367108A1 (es) | 1971-05-01 |
Family
ID=24930955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES367108A Expired ES367108A1 (es) | 1968-05-15 | 1969-05-12 | Un procedimiento para la preparacion de acido (cis-1,2-epo-xipropil) fosfonico y derivados del mismo |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3597451A (es) |
| BE (1) | BE733049A (es) |
| BR (1) | BR6908834D0 (es) |
| CH (1) | CH522686A (es) |
| DE (1) | DE1924098A1 (es) |
| ES (1) | ES367108A1 (es) |
| GB (1) | GB1227119A (es) |
| IL (1) | IL32133A0 (es) |
| NL (1) | NL6905270A (es) |
| SE (1) | SE362435B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1065240B (it) * | 1976-08-04 | 1985-02-25 | Stabil Bioterapico Farmachim | Procedimento di fabbricazione di fosfomicina |
| CN102850394B (zh) * | 2012-10-10 | 2015-06-03 | 江苏倍合德化工有限公司 | 一种顺丙烯膦酸的制备方法 |
-
1968
- 1968-05-15 US US729423A patent/US3597451A/en not_active Expired - Lifetime
-
1969
- 1969-04-01 SE SE04617/69A patent/SE362435B/xx unknown
- 1969-04-03 NL NL6905270A patent/NL6905270A/xx unknown
- 1969-05-01 IL IL32133A patent/IL32133A0/xx unknown
- 1969-05-12 ES ES367108A patent/ES367108A1/es not_active Expired
- 1969-05-12 GB GB1227119D patent/GB1227119A/en not_active Expired
- 1969-05-12 DE DE19691924098 patent/DE1924098A1/de active Pending
- 1969-05-14 BE BE733049D patent/BE733049A/xx unknown
- 1969-05-14 BR BR208834/69A patent/BR6908834D0/pt unknown
- 1969-05-14 CH CH742869A patent/CH522686A/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE1924098A1 (de) | 1970-01-15 |
| BE733049A (es) | 1969-11-14 |
| CH522686A (de) | 1972-06-30 |
| SE362435B (es) | 1973-12-10 |
| IL32133A0 (en) | 1969-07-30 |
| BR6908834D0 (pt) | 1973-01-09 |
| GB1227119A (es) | 1971-04-07 |
| US3597451A (en) | 1971-08-03 |
| NL6905270A (es) | 1969-11-18 |
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