ES360075A1 - 7-heterocyclic codides and morphides - Google Patents
7-heterocyclic codides and morphidesInfo
- Publication number
- ES360075A1 ES360075A1 ES360075A ES360075A ES360075A1 ES 360075 A1 ES360075 A1 ES 360075A1 ES 360075 A ES360075 A ES 360075A ES 360075 A ES360075 A ES 360075A ES 360075 A1 ES360075 A1 ES 360075A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- possibly
- formula
- morphides
- codides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/09—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems
- C07D489/10—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14
- C07D489/12—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: containing 4aH-8, 9 c-Iminoethano- phenanthro [4, 5-b, c, d] furan ring systems condensed with carbocyclic rings or ring systems with a bridge between positions 6 and 14 the bridge containing only two carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Analgesic compositions in the form of injectable solutions or unit dosages for oral administration, comprise compounds of formula their non-toxic acid addition salts and their alkali metal salts (when R 1 =H) wherein R 1 is H or C 1-4 alkyl or C 2-5 alkanoyl, R 2 is H, CN, propargyl, C 1-4 alkyl (possibly Ph-substituted), C 2-6 alkenyl or cycloalkylmethyl (C 4-7 ), R 3 is H or Me, Y is -CH:CH- or -CH 2 CH 2 -, Q is a group of formula where R 4 is H or C 1-7 alkyl, is -NR 5 N=, -ON= or -N=C(NH 2 )N=, and R 5 is H, C 1-4 alkyl, Ph (possibly halo, CF 3 or C 1-4 alkyl or alkoxy substituted), pyridyl, quinolyl, benzothiazolyl, dimethylpyrimidyl or dimethyl-s-triazinyl. These compounds may be adminstered in combination with salicylates such as aspirin.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69731568A | 1968-01-12 | 1968-01-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES360075A1 true ES360075A1 (en) | 1970-11-01 |
Family
ID=24800650
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES360075A Expired ES360075A1 (en) | 1968-01-12 | 1968-11-11 | 7-heterocyclic codides and morphides |
Country Status (12)
| Country | Link |
|---|---|
| AT (1) | AT289304B (en) |
| BE (1) | BE724258A (en) |
| BR (1) | BR6804270D0 (en) |
| CH (1) | CH511232A (en) |
| DE (1) | DE1809234A1 (en) |
| ES (1) | ES360075A1 (en) |
| GB (1) | GB1243838A (en) |
| IL (1) | IL31080A (en) |
| LU (1) | LU57650A1 (en) |
| NL (1) | NL6816641A (en) |
| SE (1) | SE346789B (en) |
| ZM (1) | ZM18968A1 (en) |
-
1968
- 1968-11-08 GB GB53147/68A patent/GB1243838A/en not_active Expired
- 1968-11-11 ES ES360075A patent/ES360075A1/en not_active Expired
- 1968-11-13 SE SE15400/68A patent/SE346789B/xx unknown
- 1968-11-15 DE DE19681809234 patent/DE1809234A1/en active Pending
- 1968-11-17 IL IL31080A patent/IL31080A/en unknown
- 1968-11-18 CH CH1718568A patent/CH511232A/en not_active IP Right Cessation
- 1968-11-19 AT AT1122868A patent/AT289304B/en not_active IP Right Cessation
- 1968-11-21 NL NL6816641A patent/NL6816641A/xx unknown
- 1968-11-21 BE BE724258D patent/BE724258A/xx unknown
- 1968-11-22 BR BR204270/68A patent/BR6804270D0/en unknown
- 1968-12-23 LU LU57650D patent/LU57650A1/xx unknown
- 1968-12-30 ZM ZM189/68A patent/ZM18968A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH511232A (en) | 1971-08-15 |
| ZM18968A1 (en) | 1969-06-17 |
| IL31080A0 (en) | 1969-01-29 |
| GB1243838A (en) | 1971-08-25 |
| SE346789B (en) | 1972-07-17 |
| IL31080A (en) | 1972-06-28 |
| AT289304B (en) | 1971-04-13 |
| NL6816641A (en) | 1969-07-15 |
| DE1809234A1 (en) | 1969-08-14 |
| BE724258A (en) | 1969-05-21 |
| BR6804270D0 (en) | 1973-02-08 |
| LU57650A1 (en) | 1969-04-15 |
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