ES359545A1 - A procedure for the preparation of benzotiazepine derivatives. (Machine-translation by Google Translate, not legally binding)
- Google Patents
A procedure for the preparation of benzotiazepine derivatives. (Machine-translation by Google Translate, not legally binding)
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Tanabe Seiyaku Co Ltd
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Tanabe Seiyaku Co Ltd
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Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members
(AREA)
Abstract
A procedure for the preparation of benzothiazepine derivatives of the formula: **(See formula)** where R1 is a phenyl group substituted or not by 1 to 3 lower alkyl groups, lower alkoxy groups or halogen atoms, R2 is a hydrogen atom or a lower alkanoyl group, R3 and R4 are both a lower alkyl group, X is a hydrogen atom or a halogen atom and Y is an alkylene group of 2 or 3 carbon atoms, or their non-toxic acid addition salts, the procedure of which is to react an alkali metal salt of the compound of formula: **(See formula)** where R1 and X are as defined above, with an aminoalkyl halide of the formula: **(See formula)** where R3, R4 and Y are as defined above and Z is a halogen atom and optionally acylating the resulting compound in the usual way. (Machine-translation by Google Translate, not legally binding)
ES359545A1967-10-281968-10-25A procedure for the preparation of benzotiazepine derivatives. (Machine-translation by Google Translate, not legally binding)
ExpiredES359545A1
(en)