ES356705A1 - Procedure for the obtaining of compounds of coronariodilator and antiarrhythmic action. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the obtaining of compounds of coronariodilator and antiarrhythmic action. (Machine-translation by Google Translate, not legally binding)
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Centre Europeen de Recherches Mauvernay CERM
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Centre Europeen de Recherches Mauvernay CERM
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Priority claimed from FR143676Aexternal-prioritypatent/FR352F/fr
Application filed by Centre Europeen de Recherches Mauvernay CERMfiledCriticalCentre Europeen de Recherches Mauvernay CERM
Publication of ES356705A1publicationCriticalpatent/ES356705A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Procedure for obtaining a new family of chemical compounds, particularly usable as medicines with coronary dilating and anti-arrhythmic action, characterized by the general formula **(See formula)** in which; R represents a substituted or unsubstituted aryl radical, A represents a tertiary amine grouping included in a heterocycle, and R1 represents an aromatic radical substituted or not in the nucleus, or an arylalkyl radical, said process consisting in esterifying, by means of the chloride of acid corresponding to the significance of R1 in benzene medium and in the presence of a tertiary amine, preferably triethylamine, amino alcohols of the formula **(See formula)** obtained in turn by treating the phenol corresponding to R by epichlorohydrin in alkaline medium to obtain the 3-phenoxy, 1-2-epoxy propanes, and then treating the latter by a secondary amine. (Machine-translation by Google Translate, not legally binding)
ES356705A1968-03-141968-07-31Procedure for the obtaining of compounds of coronariodilator and antiarrhythmic action. (Machine-translation by Google Translate, not legally binding)
ExpiredES356705A1
(en)
Procedure for obtaining new derivatives of 4-amino-5-chlorine-N- (2- (diethylamine) -etil) -o-anisamide. (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of new heterociclic compounds of nitrogenated structure. (Machine-translation by Google Translate, not legally binding)