ES347448A1 - New procedure for the obtaining of 2-hidroxi-3-ariloxipropil-secondary amines. (Machine-translation by Google Translate, not legally binding) - Google Patents

New procedure for the obtaining of 2-hidroxi-3-ariloxipropil-secondary amines. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES347448A1
ES347448A1 ES347448A ES347448A ES347448A1 ES 347448 A1 ES347448 A1 ES 347448A1 ES 347448 A ES347448 A ES 347448A ES 347448 A ES347448 A ES 347448A ES 347448 A1 ES347448 A1 ES 347448A1
Authority
ES
Spain
Prior art keywords
formula
translation
legally binding
google translate
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES347448A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES347448A1 publication Critical patent/ES347448A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Procedure for obtaining secondary 2-hydroxy-3-aryloxypropylamines whose formula is as follows: ArO - CH2-CHOH-CH2-NHR (I) in which Ar represents a phenyl-naphthyl-tetrahydro-naphthyl or indanyl group, either unsubstituted or substituted one or more times (preferably one to three times) by the same or different substituents from each other, for which groups can be used straight or lower branched allyl, alkenyl, alkoxy, or dialkylaminoalkyl, trifluoromethyl, nitro, or methylenedioxy groups, as well as halogen atoms, and in which R represents a straight or branched alkyl group with 1 to 5 carbon atoms, consisting of react a compounds of general formula ArO-CH2-Z (II) in which Ar has the meaning indicated above and Z represents a group (see formula) or -CHOH-OH2 -Hal (Hal = Halogen atom with a symmetric dialkyl urea of formula **(See formula)** in which R has the meaning indicated above, by melting or in a high boiling point inert organic solvent at temperatures from 180-200ºC, preferably 190-195ºC. (Machine-translation by Google Translate, not legally binding)
ES347448A 1966-11-25 1967-11-22 New procedure for the obtaining of 2-hidroxi-3-ariloxipropil-secondary amines. (Machine-translation by Google Translate, not legally binding) Expired ES347448A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEB0090015 1966-11-25

Publications (1)

Publication Number Publication Date
ES347448A1 true ES347448A1 (en) 1969-06-01

Family

ID=6985071

Family Applications (1)

Application Number Title Priority Date Filing Date
ES347448A Expired ES347448A1 (en) 1966-11-25 1967-11-22 New procedure for the obtaining of 2-hidroxi-3-ariloxipropil-secondary amines. (Machine-translation by Google Translate, not legally binding)

Country Status (8)

Country Link
JP (1) JPS4934972B1 (en)
AT (1) AT277978B (en)
CH (1) CH481059A (en)
DE (1) DE1543381A1 (en)
DK (1) DK120197B (en)
ES (1) ES347448A1 (en)
FI (1) FI48069C (en)
SE (1) SE351842B (en)

Also Published As

Publication number Publication date
CH481059A (en) 1969-11-15
FI48069C (en) 1974-06-10
SE351842B (en) 1972-12-11
DK120197B (en) 1971-04-26
FI48069B (en) 1974-02-28
AT277978B (en) 1970-01-12
DE1543381A1 (en) 1969-08-07
JPS4934972B1 (en) 1974-09-19

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