ES334817A1 - Procedimiento para la preparacion de derivados de azepina. - Google Patents
Procedimiento para la preparacion de derivados de azepina.Info
- Publication number
- ES334817A1 ES334817A1 ES334817A ES334817A ES334817A1 ES 334817 A1 ES334817 A1 ES 334817A1 ES 334817 A ES334817 A ES 334817A ES 334817 A ES334817 A ES 334817A ES 334817 A1 ES334817 A1 ES 334817A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- dibenz
- azepine
- dihydro
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001538 azepines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 3
- 239000002253 acid Substances 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- JQWHASGSAFIOCM-UHFFFAOYSA-M sodium periodate Chemical compound [Na+].[O-]I(=O)(=O)=O JQWHASGSAFIOCM-UHFFFAOYSA-M 0.000 abstract 2
- PHZJTKVENKBEPK-UHFFFAOYSA-N 1-(2-ethylsulfanyl-5,6-dihydrobenzo[b][1]benzazepin-11-yl)ethanone Chemical compound C(C)SC=1C=CC2=C(N(C3=C(CC2)C=CC=C3)C(C)=O)C1 PHZJTKVENKBEPK-UHFFFAOYSA-N 0.000 abstract 1
- VXZKQJRIAVBAKW-UHFFFAOYSA-N 1-(2-ethylsulfinyl-5,6-dihydrobenzo[b][1]benzazepin-11-yl)ethanone Chemical compound C(C)S(=O)C=1C=CC2=C(N(C3=C(CC2)C=CC=C3)C(C)=O)C1 VXZKQJRIAVBAKW-UHFFFAOYSA-N 0.000 abstract 1
- REABGEVKWMWITC-UHFFFAOYSA-N 11-(3-chloropropyl)-2-methylsulfinyl-5,6-dihydrobenzo[b][1]benzazepine Chemical compound CS(=O)C=1C=CC2=C(N(C3=C(CC2)C=CC=C3)CCCCl)C1 REABGEVKWMWITC-UHFFFAOYSA-N 0.000 abstract 1
- OUJMUPGOEUYVNF-UHFFFAOYSA-N 2-ethylsulfinyl-6,11-dihydro-5H-benzo[b][1]benzazepine Chemical compound C(C)S(=O)C=1C=CC2=C(NC3=C(CC2)C=CC=C3)C1 OUJMUPGOEUYVNF-UHFFFAOYSA-N 0.000 abstract 1
- DOMIIJMZTSKSPV-UHFFFAOYSA-N 2-methylsulfinyl-6,11-dihydro-5H-benzo[b][1]benzazepine Chemical compound CS(=O)C=1C=CC2=C(NC3=C(CC2)C=CC=C3)C1 DOMIIJMZTSKSPV-UHFFFAOYSA-N 0.000 abstract 1
- MFESCIUQSIBMSM-UHFFFAOYSA-N I-BCP Chemical compound ClCCCBr MFESCIUQSIBMSM-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 150000001414 amino alcohols Chemical class 0.000 abstract 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007800 oxidant agent Substances 0.000 abstract 1
- 230000001590 oxidative effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
- C07D223/28—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom having a single bond between positions 10 and 11
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
- C07D223/24—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines with hydrocarbon radicals, substituted by nitrogen atoms, attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1774965A CH454875A (de) | 1965-12-23 | 1965-12-23 | Verfahren zur Herstellung von neuen Azepinderivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES334817A1 true ES334817A1 (es) | 1968-03-01 |
Family
ID=4427789
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES334817A Expired ES334817A1 (es) | 1965-12-23 | 1966-12-22 | Procedimiento para la preparacion de derivados de azepina. |
Country Status (13)
| Country | Link |
|---|---|
| AT (1) | AT268289B (enEXAMPLES) |
| BE (1) | BE691640A (enEXAMPLES) |
| CH (1) | CH454875A (enEXAMPLES) |
| DE (1) | DE1695002A1 (enEXAMPLES) |
| DK (1) | DK122764B (enEXAMPLES) |
| ES (1) | ES334817A1 (enEXAMPLES) |
| FI (1) | FI44236B (enEXAMPLES) |
| FR (1) | FR1506734A (enEXAMPLES) |
| GB (1) | GB1114970A (enEXAMPLES) |
| IL (1) | IL27124A (enEXAMPLES) |
| NL (1) | NL6618038A (enEXAMPLES) |
| NO (1) | NO118920B (enEXAMPLES) |
| SE (1) | SE333736B (enEXAMPLES) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2201884B1 (enEXAMPLES) * | 1972-10-09 | 1975-11-28 | Roussel Uclaf |
-
1965
- 1965-12-23 CH CH1774965A patent/CH454875A/de unknown
-
1966
- 1966-12-16 FI FI334866A patent/FI44236B/fi active
- 1966-12-22 NO NO16611866A patent/NO118920B/no unknown
- 1966-12-22 ES ES334817A patent/ES334817A1/es not_active Expired
- 1966-12-22 DE DE19661695002 patent/DE1695002A1/de active Pending
- 1966-12-22 BE BE691640D patent/BE691640A/xx unknown
- 1966-12-22 AT AT1180666A patent/AT268289B/de active
- 1966-12-22 GB GB5740166A patent/GB1114970A/en not_active Expired
- 1966-12-22 SE SE1757566A patent/SE333736B/xx unknown
- 1966-12-22 NL NL6618038A patent/NL6618038A/xx unknown
- 1966-12-22 DK DK663366A patent/DK122764B/da unknown
- 1966-12-22 IL IL2712466A patent/IL27124A/en unknown
- 1966-12-23 FR FR88632A patent/FR1506734A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| FI44236B (enEXAMPLES) | 1971-06-30 |
| SE333736B (enEXAMPLES) | 1971-03-29 |
| DE1695002A1 (de) | 1971-03-25 |
| GB1114970A (en) | 1968-05-22 |
| BE691640A (enEXAMPLES) | 1967-06-22 |
| NL6618038A (enEXAMPLES) | 1967-06-26 |
| CH454875A (de) | 1968-04-30 |
| IL27124A (en) | 1970-10-30 |
| NO118920B (enEXAMPLES) | 1970-03-02 |
| FR1506734A (fr) | 1967-12-22 |
| DK122764B (da) | 1972-04-10 |
| AT268289B (de) | 1969-02-10 |
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