ES330696A1 - A procedure for the preparation of esters of 11 betahidroxy-17 alpha-alcanoiloxi bottom of the pregnan series. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of esters of 11 betahidroxy-17 alpha-alcanoiloxi bottom of the pregnan series. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES330696A1
ES330696A1 ES0330696A ES330696A ES330696A1 ES 330696 A1 ES330696 A1 ES 330696A1 ES 0330696 A ES0330696 A ES 0330696A ES 330696 A ES330696 A ES 330696A ES 330696 A1 ES330696 A1 ES 330696A1
Authority
ES
Spain
Prior art keywords
translation
esters
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0330696A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherico Ltd filed Critical Scherico Ltd
Publication of ES330696A1 publication Critical patent/ES330696A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)

Abstract

A process for the preparation of esters of 11 β -hydroxy-l7- β -alkoxyloxy bottom of the pregnane series characterized in that it comprises treating an ester of 11 beta -trihaloacetoxy-17 β -alkyloxy lower of the pregnane series in a lower alkanol with a salt of an acid having a pKa which falls within the range of from about 2.3 to about 7.3 whereby the 11 β -trihaloacetyl group selectively solves to become a free hydroxy group. (Machine-translation by Google Translate, not legally binding)
ES0330696A 1965-08-30 1966-08-29 A procedure for the preparation of esters of 11 betahidroxy-17 alpha-alcanoiloxi bottom of the pregnan series. (Machine-translation by Google Translate, not legally binding) Expired ES330696A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48381065A 1965-08-30 1965-08-30

Publications (1)

Publication Number Publication Date
ES330696A1 true ES330696A1 (en) 1967-06-16

Family

ID=23921623

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0330696A Expired ES330696A1 (en) 1965-08-30 1966-08-29 A procedure for the preparation of esters of 11 betahidroxy-17 alpha-alcanoiloxi bottom of the pregnan series. (Machine-translation by Google Translate, not legally binding)

Country Status (7)

Country Link
BE (1) BE686189A (en)
CH (1) CH481085A (en)
DE (1) DE1593519B2 (en)
DK (1) DK117350B (en)
ES (1) ES330696A1 (en)
GB (1) GB1097164A (en)
SE (1) SE334357B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH622811A5 (en) * 1974-03-27 1981-04-30 Plurichemie Anstalt
IL66432A0 (en) * 1981-08-04 1982-12-31 Plurichemie Anstalt Process for the preparation of steroidal esters

Also Published As

Publication number Publication date
GB1097164A (en) 1967-12-29
BE686189A (en) 1967-02-28
DE1593519A1 (en) 1970-09-03
SE334357B (en) 1971-04-26
CH481085A (en) 1969-11-15
DK117350B (en) 1970-04-20
DE1593519B2 (en) 1975-08-14

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