ES325862A1 - Procedimiento para la sintesis de flavanoides sustituidos. - Google Patents
Procedimiento para la sintesis de flavanoides sustituidos.Info
- Publication number
- ES325862A1 ES325862A1 ES0325862A ES325862A ES325862A1 ES 325862 A1 ES325862 A1 ES 325862A1 ES 0325862 A ES0325862 A ES 0325862A ES 325862 A ES325862 A ES 325862A ES 325862 A1 ES325862 A1 ES 325862A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- agents
- amino
- see formula
- groups
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 125000004387 flavanoid group Chemical group 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 4
- 125000003277 amino group Chemical group 0.000 abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 4
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
- -1 methylenedioxyethylenedioxy Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910003204 NH2 Inorganic materials 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229940100198 alkylating agent Drugs 0.000 abstract 1
- 239000002168 alkylating agent Substances 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 150000001735 carboxylic acids Chemical class 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 150000003856 quaternary ammonium compounds Chemical class 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/60—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with aryl radicals attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/32—2,3-Dihydro derivatives, e.g. flavanones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEM0064983 | 1965-04-23 | ||
DEM0066372 | 1965-08-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES325862A1 true ES325862A1 (es) | 1967-03-01 |
Family
ID=25987687
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0325862A Expired ES325862A1 (es) | 1965-04-23 | 1966-04-22 | Procedimiento para la sintesis de flavanoides sustituidos. |
Country Status (8)
Country | Link |
---|---|
US (1) | US3462455A (en, 2012) |
BE (1) | BE679916A (en, 2012) |
CH (1) | CH469698A (en, 2012) |
DE (1) | DE1518015C3 (en, 2012) |
ES (1) | ES325862A1 (en, 2012) |
FR (1) | FR6009M (en, 2012) |
GB (1) | GB1067986A (en, 2012) |
NL (1) | NL6605086A (en, 2012) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4376781A (en) * | 1978-02-27 | 1983-03-15 | Inverni Della Beffa S.P.A. | Pharmaceutical compositions |
DE3069830D1 (en) * | 1979-09-13 | 1985-01-31 | Wellcome Found | Benzopyran compounds, useful as chemotherapeutic agents |
DE3505611A1 (de) * | 1984-11-26 | 1986-05-28 | Merck Patent Gmbh, 6100 Darmstadt | Halogen-hydroxy-flavone |
US4758679A (en) * | 1986-07-18 | 1988-07-19 | Pennwalt Corporation | Preparation of 7-(3-(propylamino)-2-hydroxypropoxy)flavone |
JPH0366669A (ja) * | 1989-08-03 | 1991-03-22 | Shionogi & Co Ltd | 複素環式化合物 |
DE4011187A1 (de) * | 1990-04-06 | 1991-10-10 | Hoechst Ag | Substituierte 3-thia- bzw. 3-oxa-alkyl-flavone, verfahren zu ihrer herstellung, verwendung derselben, arzneimittel auf basis dieser verbindungen sowie zwischenprodukte |
-
1965
- 1965-04-23 DE DE1518015A patent/DE1518015C3/de not_active Expired
-
1966
- 1966-03-23 CH CH419766A patent/CH469698A/de unknown
- 1966-04-12 GB GB15897/66A patent/GB1067986A/en not_active Expired
- 1966-04-15 NL NL6605086A patent/NL6605086A/xx unknown
- 1966-04-19 US US543558A patent/US3462455A/en not_active Expired - Lifetime
- 1966-04-22 BE BE679916D patent/BE679916A/xx unknown
- 1966-04-22 FR FR58656A patent/FR6009M/fr not_active Expired
- 1966-04-22 ES ES0325862A patent/ES325862A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE1518015C3 (de) | 1974-06-06 |
CH469698A (de) | 1969-03-15 |
GB1067986A (en) | 1967-05-10 |
US3462455A (en) | 1969-08-19 |
DE1518015A1 (de) | 1969-08-14 |
FR6009M (en, 2012) | 1968-05-06 |
NL6605086A (en, 2012) | 1966-10-24 |
BE679916A (en, 2012) | 1966-10-24 |
DE1518015B2 (de) | 1973-10-25 |
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