ES325588A1 - Procedure for the preparation of new halogenated compounds of the pregnanos series. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new halogenated compounds of the pregnanos series. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES325588A1
ES325588A1 ES0325588A ES325588A ES325588A1 ES 325588 A1 ES325588 A1 ES 325588A1 ES 0325588 A ES0325588 A ES 0325588A ES 325588 A ES325588 A ES 325588A ES 325588 A1 ES325588 A1 ES 325588A1
Authority
ES
Spain
Prior art keywords
formula
procedure
translation
series
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0325588A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Original Assignee
Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Spojene Podniky Pro Zdravotnickou Vyrobu filed Critical Spofa Spojene Podniky Pro Zdravotnickou Vyrobu
Publication of ES325588A1 publication Critical patent/ES325588A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the preparation of new halogenated compounds of the series of pregnanes having the formula I as a general formula ** (See formula) ** X in this general formula I representing a halogen atom, especially fluorine, chlorine, bromine; R represents in it an alkyl having 1-5 carbon atoms, while another double bond can also exist in position 1, 2, whose procedure is characterized by the simultaneous etherification and enolization of a 6-halogeno- derivative. 17-methylene-17 alpha-acyloxyprogesterone having the formula II as its general formula ** (See formula) ** having X and R here, the same significance as in formula I, substituent X in position 6 may be of alpha, or beta, configuration is continued with dehydrogenation in the 6,7 position of 3-alkoxy-6-halogen -Delta 3,5-dieno corresponding that has just obtained and that has as a general formula the partial formula III ** (See formula) ** R 'representing in this formula III an alkyl having 1-6 carbon atoms; X having the same significance here as in formula I, being in the course of the dehydrogenation phase in position 6.7 of the derivative having formula III when it is possible to introduce simultaneously the double bond in position 1,2. (Machine-translation by Google Translate, not legally binding)
ES0325588A 1965-04-16 1966-04-15 Procedure for the preparation of new halogenated compounds of the pregnanos series. (Machine-translation by Google Translate, not legally binding) Expired ES325588A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS251165 1965-04-16

Publications (1)

Publication Number Publication Date
ES325588A1 true ES325588A1 (en) 1967-05-01

Family

ID=5362468

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0325588A Expired ES325588A1 (en) 1965-04-16 1966-04-15 Procedure for the preparation of new halogenated compounds of the pregnanos series. (Machine-translation by Google Translate, not legally binding)

Country Status (9)

Country Link
AT (1) AT268551B (en)
BE (1) BE679507A (en)
CH (1) CH477429A (en)
DE (1) DE1593356A1 (en)
ES (1) ES325588A1 (en)
GB (2) GB1149102A (en)
LU (1) LU50912A1 (en)
NL (1) NL6605137A (en)
SE (1) SE313563B (en)

Also Published As

Publication number Publication date
LU50912A1 (en) 1966-06-15
DE1593356A1 (en) 1970-07-30
NL6605137A (en) 1966-10-17
CH477429A (en) 1969-08-31
GB1149102A (en) 1969-04-16
AT268551B (en) 1969-02-10
SE313563B (en) 1969-08-18
GB1149101A (en) 1969-04-16
BE679507A (en) 1966-09-16

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