GB1149101A - A method of preparing halogenated compounds of the pregnane series - Google Patents
A method of preparing halogenated compounds of the pregnane seriesInfo
- Publication number
- GB1149101A GB1149101A GB1680066A GB1680066A GB1149101A GB 1149101 A GB1149101 A GB 1149101A GB 1680066 A GB1680066 A GB 1680066A GB 1680066 A GB1680066 A GB 1680066A GB 1149101 A GB1149101 A GB 1149101A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methylene
- pregna
- dehydrogenation
- dione
- diene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1,149,101. 6 - Halo - 16 - methylene - pregnenes. SPOFA SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU. 18 April, 1966 [16 April, 1965], No. 16800/66. Heading C2U. The invention comprises (a) a process for preparing compounds of formula wherein X is a halogen atom and R is a C 1-15 alkyl group, and 1,2-dehydro-derivatives thereof, by conversion of a corresponding 6-halopregn - 4 - ene to its 3 - (C 1-6 alkoxy) - enol ether and subjecting this to 6,7-dehydrogenation, with optional simultaneous or subsequent 1,2-dehydrogenation, and (b) 6-bromo-16-methylene - 17α - acetoxy - pregna - 4,6 - diene - 3,20- dione and 6-chloro-16-methylene-17α-caproyloxy-pregna-4,6-diene-3,20-dione. The products of the invention have progestational activity and may be used in pharmaceutical compositions in forms suitable for oral, parenteral or rectal administration.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CS251165 | 1965-04-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1149101A true GB1149101A (en) | 1969-04-16 |
Family
ID=5362468
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1680066A Expired GB1149101A (en) | 1965-04-16 | 1966-04-18 | A method of preparing halogenated compounds of the pregnane series |
GB4544068A Expired GB1149102A (en) | 1965-04-16 | 1966-04-18 | A method of preparing new halogenated compounds of the pregnane series |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4544068A Expired GB1149102A (en) | 1965-04-16 | 1966-04-18 | A method of preparing new halogenated compounds of the pregnane series |
Country Status (9)
Country | Link |
---|---|
AT (1) | AT268551B (en) |
BE (1) | BE679507A (en) |
CH (1) | CH477429A (en) |
DE (1) | DE1593356A1 (en) |
ES (1) | ES325588A1 (en) |
GB (2) | GB1149101A (en) |
LU (1) | LU50912A1 (en) |
NL (1) | NL6605137A (en) |
SE (1) | SE313563B (en) |
-
1966
- 1966-04-14 BE BE679507D patent/BE679507A/xx unknown
- 1966-04-15 ES ES0325588A patent/ES325588A1/en not_active Expired
- 1966-04-15 CH CH548966A patent/CH477429A/en not_active IP Right Cessation
- 1966-04-15 NL NL6605137A patent/NL6605137A/xx unknown
- 1966-04-15 SE SE514966A patent/SE313563B/xx unknown
- 1966-04-15 LU LU50912A patent/LU50912A1/xx unknown
- 1966-04-16 DE DE19661593356 patent/DE1593356A1/en active Pending
- 1966-04-18 GB GB1680066A patent/GB1149101A/en not_active Expired
- 1966-04-18 AT AT363866A patent/AT268551B/en active
- 1966-04-18 GB GB4544068A patent/GB1149102A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
DE1593356A1 (en) | 1970-07-30 |
GB1149102A (en) | 1969-04-16 |
LU50912A1 (en) | 1966-06-15 |
CH477429A (en) | 1969-08-31 |
NL6605137A (en) | 1966-10-17 |
ES325588A1 (en) | 1967-05-01 |
BE679507A (en) | 1966-09-16 |
AT268551B (en) | 1969-02-10 |
SE313563B (en) | 1969-08-18 |
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