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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of ES317706A1publicationCriticalpatent/ES317706A1/en
A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
A61K31/00—Medicinal preparations containing organic active ingredients
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
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Nitrogen Condensed Heterocyclic Rings
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Abstract
A process for preparing benzodiazepine derivatives, characterized in that it consists of reacting a compound of the general formula ** (See formula) ** where R1 and R2 represent hydrogen, halogen, trifluoromethyl, nitro, amino or cyano, while R4 represents hydrogen, lower alkyl or lower alkenyl, with a lower alkanoyl anhydride, an aroyl anhydride, a lower aralkyl anhydride, a dialkyl lower sulphide, a diaryl sulphide, a lower diarylcanoyl sulphide, a lower alkanoyl halide, an aroyl halide or an aralkanoyl halide lower, in treating, if desired, the compound thus obtained with a hydrolyzing agent and/or a lower alkanol and in converting, if desired, any product of the reaction in an acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES0317706A1964-09-231965-09-22A procedure for preparing benzodiazepine derivatives. (Machine-translation by Google Translate, not legally binding)
ExpiredES317706A1
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