ES315101A1 - Procedimiento de preparaciën de nuevos derivados de tetraciclina - Google Patents
Procedimiento de preparaciën de nuevos derivados de tetraciclinaInfo
- Publication number
- ES315101A1 ES315101A1 ES0315101A ES315101A ES315101A1 ES 315101 A1 ES315101 A1 ES 315101A1 ES 0315101 A ES0315101 A ES 0315101A ES 315101 A ES315101 A ES 315101A ES 315101 A1 ES315101 A1 ES 315101A1
- Authority
- ES
- Spain
- Prior art keywords
- tetracycline
- acid
- sulphate
- salt
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003839 salts Chemical class 0.000 title abstract 7
- 229940072172 tetracycline antibiotic Drugs 0.000 title abstract 4
- 239000004098 Tetracycline Substances 0.000 abstract 7
- 239000002253 acid Substances 0.000 abstract 7
- 229960002180 tetracycline Drugs 0.000 abstract 7
- 229930101283 tetracycline Natural products 0.000 abstract 7
- 235000019364 tetracycline Nutrition 0.000 abstract 7
- -1 tetracycline cetyl sulphate Chemical class 0.000 abstract 4
- 150000002148 esters Chemical class 0.000 abstract 3
- 150000003522 tetracyclines Chemical class 0.000 abstract 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- DHPRQBPJLMKORJ-XRNKAMNCSA-N (4s,4as,5as,6s,12ar)-7-chloro-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide Chemical compound C1=CC(Cl)=C2[C@](O)(C)[C@H]3C[C@H]4[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]4(O)C(=O)C3=C(O)C2=C1O DHPRQBPJLMKORJ-XRNKAMNCSA-N 0.000 abstract 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
- 239000004100 Oxytetracycline Substances 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- CYDMQBQPVICBEU-UHFFFAOYSA-N chlorotetracycline Natural products C1=CC(Cl)=C2C(O)(C)C3CC4C(N(C)C)C(O)=C(C(N)=O)C(=O)C4(O)C(O)=C3C(=O)C2=C1O CYDMQBQPVICBEU-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 150000002334 glycols Chemical class 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 abstract 1
- 229960000625 oxytetracycline Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- HMEYVGGHISAPJR-IAHYZSEUSA-N rolitetracycline Chemical compound O=C([C@@]1(O)C(O)=C2[C@@H]([C@](C3=CC=CC(O)=C3C2=O)(C)O)C[C@H]1[C@@H](C=1O)N(C)C)C=1C(=O)NCN1CCCC1 HMEYVGGHISAPJR-IAHYZSEUSA-N 0.000 abstract 1
- GGHPAKFFUZUEKL-UHFFFAOYSA-M sodium;hexadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCOS([O-])(=O)=O GGHPAKFFUZUEKL-UHFFFAOYSA-M 0.000 abstract 1
- NWZBFJYXRGSRGD-UHFFFAOYSA-M sodium;octadecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCCCCCOS([O-])(=O)=O NWZBFJYXRGSRGD-UHFFFAOYSA-M 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- KDYFGRWQOYBRFD-UHFFFAOYSA-L succinate(2-) Chemical compound [O-]C(=O)CCC([O-])=O KDYFGRWQOYBRFD-UHFFFAOYSA-L 0.000 abstract 1
- 229910021653 sulphate ion Inorganic materials 0.000 abstract 1
- 229940095064 tartrate Drugs 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
- 235000015112 vegetable and seed oil Nutrition 0.000 abstract 1
- 239000008158 vegetable oil Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES0315101A ES315101A1 (es) | 1965-07-08 | 1965-07-08 | Procedimiento de preparaciën de nuevos derivados de tetraciclina |
| DE1966F0049063 DE1568519B1 (de) | 1965-07-08 | 1966-04-29 | Herstellung von Laurylsulfaten von Tetracyclinen |
| BR180566/66A BR6680566D0 (pt) | 1965-07-08 | 1966-06-20 | Processo para a obtencao de novos derivados de tetraciclina |
| NL6609490A NL6609490A (OSRAM) | 1965-07-08 | 1966-07-06 | |
| GB30878/66A GB1155037A (en) | 1965-07-08 | 1966-07-08 | Salts of Tetracycline Antibiotics |
| BE709002D BE709002A (OSRAM) | 1965-07-08 | 1968-01-05 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES0315101A ES315101A1 (es) | 1965-07-08 | 1965-07-08 | Procedimiento de preparaciën de nuevos derivados de tetraciclina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES315101A1 true ES315101A1 (es) | 1966-01-01 |
Family
ID=8442667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0315101A Expired ES315101A1 (es) | 1965-07-08 | 1965-07-08 | Procedimiento de preparaciën de nuevos derivados de tetraciclina |
Country Status (5)
| Country | Link |
|---|---|
| BR (1) | BR6680566D0 (OSRAM) |
| DE (1) | DE1568519B1 (OSRAM) |
| ES (1) | ES315101A1 (OSRAM) |
| GB (1) | GB1155037A (OSRAM) |
| NL (1) | NL6609490A (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2144737A (en) * | 1983-08-02 | 1985-03-13 | American Cyanamid Co | Novel alkyl suphate of antibiotics of the tetracycline series |
| DE10114245A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Herstellung und Verwendung einer Antibiotikum-/Antibiotika-Zubereitung |
| DE10114364A1 (de) * | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Verfahren zur Herstellung von antibiotischen Kompositen |
| DE10114244A1 (de) | 2001-03-22 | 2002-10-02 | Heraeus Kulzer Gmbh & Co Kg | Antibiotikum-/Antibiotika-Zubereitung mit retardierender Wirkstofffreisetzung |
| IS6389A (is) | 2001-08-31 | 2003-03-03 | Heraeus Kulzer Gmbh & Co. Kg | Reynsla af sýklalyfjahúðun skrokka, sem í eru örholrými, og einnig af þannig húðuðum skrokkum og notkun þeirra |
| US20210186879A1 (en) * | 2016-03-07 | 2021-06-24 | Double Bond Pharmaceuticals Ab | Targeted delivery of hydrophilic drugs to lung |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1098974A (fr) * | 1954-01-08 | 1955-08-29 | Rhone Poulenc Sa | Nouveaux esters de la tétracycline et leur procédé de préparation |
| DE1076682B (de) * | 1958-05-10 | 1960-03-03 | Amalie Schoog Geb Luetzenkirch | Verfahren zur Herstellung von schwerloeslichen Tetracyclinsalzen |
| FR1356997A (fr) * | 1963-02-11 | 1964-04-03 | Soc Ind Fab Antibiotiques Sifa | Nouveaux dérivés de la tétracycline et procédé de préparation |
| GB1065715A (en) * | 1964-04-16 | 1967-04-19 | Pfizer & Co C | Tetracycline derivatives |
-
1965
- 1965-07-08 ES ES0315101A patent/ES315101A1/es not_active Expired
-
1966
- 1966-04-29 DE DE1966F0049063 patent/DE1568519B1/de not_active Withdrawn
- 1966-06-20 BR BR180566/66A patent/BR6680566D0/pt unknown
- 1966-07-06 NL NL6609490A patent/NL6609490A/xx unknown
- 1966-07-08 GB GB30878/66A patent/GB1155037A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1568519B1 (de) | 1970-05-21 |
| GB1155037A (en) | 1969-06-11 |
| NL6609490A (OSRAM) | 1967-01-09 |
| BR6680566D0 (pt) | 1973-12-26 |
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