ES308478A1 - A procedure for the preparation of benzodiazepine derivatives. (Machine-translation by Google Translate, not legally binding)
- Google Patents
A procedure for the preparation of benzodiazepine derivatives. (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US412325Aexternal-prioritypatent/US3215688A/en
Application filed by F Hoffmann La Roche AGfiledCriticalF Hoffmann La Roche AG
Publication of ES308478A1publicationCriticalpatent/ES308478A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
A procedure for the preparation of benzodiazepine derivatives of the general formula **(See formula)** where R1 represents amino, lower alkanoylamino, lower alkylidonamino or phenylalkylidonamino lower, R2 represents hydrogen or lower alkyl, represents phenyl, pyridyl, halophenyl, trifluoromethylphenyl, lower alkylphenyl, nitrophenyl or lower alkoxyphenyl, represents hydrogen, halogen, nitro, trifluoromethyl, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulfinyl, or lower alkylsulfonyl, and the corresponding 4-oxides and acid addition salts of such compounds, a process consisting of treating the 1-sodium derivative of a compound of the formula **(See formula)** where R2, R3 and R4 have the same meaning as explained before, or a corresponding 4-oxide, with chloramine; if desired, alkanoylate the product obtained or react it with a compound of the formula R = O III wherein R represents a lower alkylidene or lower phenylalkylidene group, and, if desired, converting a reaction basic product into an acid addition salt thereof. (Machine-translation by Google Translate, not legally binding)
ES0308478A1964-01-241965-01-23A procedure for the preparation of benzodiazepine derivatives. (Machine-translation by Google Translate, not legally binding)
ExpiredES308478A1
(en)