ES304697A3 - A procedure for the preparation of new esters of lan- (beta-oxyethyl) -N-gamma - (3-chloro-10-phenythyacinyl) - propylpiperazine. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of new esters of lan- (beta-oxyethyl) -N-gamma - (3-chloro-10-phenythyacinyl) - propylpiperazine. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES304697A3 ES304697A3 ES0304697A ES304697A ES304697A3 ES 304697 A3 ES304697 A3 ES 304697A3 ES 0304697 A ES0304697 A ES 0304697A ES 304697 A ES304697 A ES 304697A ES 304697 A3 ES304697 A3 ES 304697A3
- Authority
- ES
- Spain
- Prior art keywords
- chloro
- general formula
- formula
- oxyethyl
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A process for the preparation of new esters of N - (β -oxyethyl) -N '- [γ-( 3'-chloro-10'-phenothiazinyl) -propyl-] - piperazine of general formula I: ** (See formula) ** in which R is a cyclic radical optionally substituted or a group containing one or more optionally substituted cyclic radicals, as well as their salts, characterized in that in the nitrogen atom of 3-chlorophenothiazine, the substituent of formula II is formed by condensation: ** (See formula) ** wherein R has the above significance, so that: a) 3-chloro-10 (γ -piperazino) -propyl-phenothiazine is reacted with a compound of general formula III: Y-CH2-CH2-O-CO-R, (III) wherein Y means an ester residue capable of reacting such as a halogen atom, a sulfuric acid ester group or an aliphatic or aromatic sulfonic acid ester residue, and R has the above significance, or b) a phenothiazine derivative of general formula IV: ** (See formula) ** with a piperazine derivative of general formula V: ** (See formula) ** in which Y and R have the above significance, or c) 3-chlorophenothiazine is reacted with a piperazine derivative of general formula VI: ** (See formula) ** in which Y and R have the above meaning, or with a salt thereof, and eventually the esters obtained in their salts are transformed by the addition of acid. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES0304697A ES304697A3 (en) | 1964-10-06 | 1964-10-06 | A procedure for the preparation of new esters of lan- (beta-oxyethyl) -N-gamma - (3-chloro-10-phenythyacinyl) - propylpiperazine. (Machine-translation by Google Translate, not legally binding) |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES0304697A ES304697A3 (en) | 1964-10-06 | 1964-10-06 | A procedure for the preparation of new esters of lan- (beta-oxyethyl) -N-gamma - (3-chloro-10-phenythyacinyl) - propylpiperazine. (Machine-translation by Google Translate, not legally binding) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES304697A3 true ES304697A3 (en) | 1965-08-16 |
Family
ID=34498959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0304697A Expired ES304697A3 (en) | 1964-10-06 | 1964-10-06 | A procedure for the preparation of new esters of lan- (beta-oxyethyl) -N-gamma - (3-chloro-10-phenythyacinyl) - propylpiperazine. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES304697A3 (en) |
-
1964
- 1964-10-06 ES ES0304697A patent/ES304697A3/en not_active Expired
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