ES3013497T3 - Improved administration of glycylcyclines by inhalation for the treatment of pulmonary infections with mycobacterium abscessus - Google Patents

Improved administration of glycylcyclines by inhalation for the treatment of pulmonary infections with mycobacterium abscessus Download PDF

Info

Publication number
ES3013497T3
ES3013497T3 ES20729969T ES20729969T ES3013497T3 ES 3013497 T3 ES3013497 T3 ES 3013497T3 ES 20729969 T ES20729969 T ES 20729969T ES 20729969 T ES20729969 T ES 20729969T ES 3013497 T3 ES3013497 T3 ES 3013497T3
Authority
ES
Spain
Prior art keywords
glycylcycline
use according
subject
treatment
infection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES20729969T
Other languages
English (en)
Spanish (es)
Inventor
Ingen Jakobus Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Stichting Radboud Universitair Medisch Centrum
Original Assignee
Stichting Radboud Universitair Medisch Centrum
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Radboud Universitair Medisch Centrum filed Critical Stichting Radboud Universitair Medisch Centrum
Application granted granted Critical
Publication of ES3013497T3 publication Critical patent/ES3013497T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
ES20729969T 2019-05-24 2020-05-25 Improved administration of glycylcyclines by inhalation for the treatment of pulmonary infections with mycobacterium abscessus Active ES3013497T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP19176477 2019-05-24
PCT/EP2020/064444 WO2020239696A1 (en) 2019-05-24 2020-05-25 Improved administration of glycylcyclines by inhalation

Publications (1)

Publication Number Publication Date
ES3013497T3 true ES3013497T3 (en) 2025-04-14

Family

ID=66647271

Family Applications (1)

Application Number Title Priority Date Filing Date
ES20729969T Active ES3013497T3 (en) 2019-05-24 2020-05-25 Improved administration of glycylcyclines by inhalation for the treatment of pulmonary infections with mycobacterium abscessus

Country Status (4)

Country Link
US (1) US20220233555A1 (de)
EP (2) EP3976050B1 (de)
ES (1) ES3013497T3 (de)
WO (1) WO2020239696A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT202100031133A1 (it) 2021-12-13 2023-06-13 Zambon Spa Composizione farmaceutica comprendente tigeciclina

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4069819A (en) 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
IT1228459B (it) 1989-02-23 1991-06-19 Phidea S R L Inalatore con svuotamento regolare e completo della capsula.
US5494903A (en) 1991-10-04 1996-02-27 American Cyanamid Company 7-substituted-9-substituted amino-6-demethyl-6-deoxytetracyclines
US5284963A (en) 1992-08-13 1994-02-08 American Cyanamid Company Method of producing 7-(substituted)-9-[(substituted glycyl)-amidol]-6-demethyl-6-deoxytetra-cyclines
JPH10501519A (ja) 1994-03-07 1998-02-10 インヘイル・セラピューティック・システムズ インシュリンを肺に送給できる方法および組成物
US6766799B2 (en) 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
WO2007145868A1 (en) * 2006-06-07 2007-12-21 Wyeth Treating cystic fibrosis with antibiotics via an aerosol drug
US20110142914A1 (en) 2007-12-06 2011-06-16 Cytotech Labs, Llc Inhalable compositions having enhanced bioavailability
UA107095C2 (uk) 2009-12-14 2014-11-25 Антибіотичні мікрочастинки для інгаляції
CN103044281A (zh) 2013-01-02 2013-04-17 湖南赛隆药业有限公司 高纯度替加环素的制法
CN105705138A (zh) 2013-08-26 2016-06-22 卡迪斯制药公司 具有改进的化学性质的氨基糖苷类物质和磷霉素的组合制剂
SG11201700621XA (en) * 2014-07-25 2017-02-27 Agency Science Tech & Res Antibiotic compositions for treating bacterial infections

Also Published As

Publication number Publication date
EP3976050A1 (de) 2022-04-06
EP4523754A2 (de) 2025-03-19
US20220233555A1 (en) 2022-07-28
EP3976050C0 (de) 2025-01-22
EP4523754A3 (de) 2025-05-07
EP3976050B1 (de) 2025-01-22
WO2020239696A1 (en) 2020-12-03

Similar Documents

Publication Publication Date Title
US11116765B2 (en) Liposomal ciprofloxacin formulations with activity against non-tuberculous mycobacteria
AU778797B2 (en) Method for the treatment of severe chronic bronchitis (bronchiectasis) with an aerosolized antibiotic
US9968555B2 (en) Liposomal formulations that form drug nanocrystals after freeze-thaw
KR20170005104A (ko) 폐의 비-결핵성 마이코박테리아 감염을 치료하기 위한 방법
ES3013497T3 (en) Improved administration of glycylcyclines by inhalation for the treatment of pulmonary infections with mycobacterium abscessus
WO2021091801A1 (en) Compositions of clofazimine, combinations comprising them, processes for their preparation, uses and methods of treatment comprising them
WO2020123336A1 (en) Compositions of bedaquiline, combinations comprising them, processes for their preparation, uses and methods of treatment comprising them
CA3067858A1 (en) Method for reducing lung infection
Balducci et al. Drug delivery strategies for pulmonary administration of antibiotics
CN110312514A (zh) 用于治疗肺部细菌感染的氨基糖苷增强剂
US20210007985A1 (en) Liposomal anti-infective formulations to inhibit non-tuberculous mycobacteria (ntm) microaggregate formation and establishment of ntm biofilm
Chen Identification of Synergistic Drug Combinations against Cystic Fibrosis Pathogens
WO2024180569A1 (en) A synergistic aqueous nebulization suspension for management of infectious respiratory disorders and process of preparation
HK40076544B (en) Systems for treating pulmonary infections
EP4132463A1 (de) Inhalierbare formulierung
MXPA01006134A (en) Method for the treatment of severe chronic bronchitis (bronchiectasis) with an aerosolized antibiotic
HK1202812B (en) Systems for treating pulmonary infections