ES301102A1 - Procedimiento para la obtencion de nuevas dihidrotieno 3-2-dipirimidinas. - Google Patents
Procedimiento para la obtencion de nuevas dihidrotieno 3-2-dipirimidinas.Info
- Publication number
- ES301102A1 ES301102A1 ES0301102A ES301102A ES301102A1 ES 301102 A1 ES301102 A1 ES 301102A1 ES 0301102 A ES0301102 A ES 0301102A ES 301102 A ES301102 A ES 301102A ES 301102 A1 ES301102 A1 ES 301102A1
- Authority
- ES
- Spain
- Prior art keywords
- lower alkyl
- group
- optionally
- mercapto group
- free
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DET0022407 | 1962-07-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES301102A1 true ES301102A1 (es) | 1965-01-16 |
Family
ID=7550528
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES0301102A Expired ES301102A1 (es) | 1962-07-04 | 1964-06-16 | Procedimiento para la obtencion de nuevas dihidrotieno 3-2-dipirimidinas. |
Country Status (5)
Country | Link |
---|---|
US (3) | US3272811A (es) |
DE (1) | DE1470336A1 (es) |
ES (1) | ES301102A1 (es) |
GB (1) | GB1048986A (es) |
NL (1) | NL6504085A (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3931204A (en) * | 1971-07-13 | 1976-01-06 | U.C.B. Societe Anonyme | Thieno[3,4-d]pyrimidines |
US3960860A (en) * | 1973-01-08 | 1976-06-01 | International Flavors & Fragrances Inc. | 2-Methyl-5,7-dihydrothieno-[3,4d]-pyrimidine |
US4287340A (en) * | 1979-08-27 | 1981-09-01 | Warner-Lambert Company | Dihydro-oxo-pyrido[1,2-a]thienopyrimidine compounds |
NL8300656A (nl) * | 1982-02-25 | 1983-09-16 | Maruko Pharmaceutical Co | Thiopyranopyrimidineverbindingen en zuuradditiezouten daarvan. |
DE3335472A1 (de) * | 1983-09-30 | 1985-04-11 | Gödecke AG, 1000 Berlin | 5h-(1)benzopyrano-(2,3,-d)pyrimidin-derivate, verfahren zu deren herstellung sowie deren verwendung bei der bekaempfung von gastralen und duodenalen schleimhautlaesionen |
DE3335473A1 (de) * | 1983-09-30 | 1985-04-11 | Gödecke AG, 1000 Berlin | 4-thioxo-benzopyrano(2,3-d)pyrimidin-derivate sowie verfahren zu deren herstellung |
US4670560A (en) * | 1986-04-28 | 1987-06-02 | Ortho Pharmaceutical Corporation | Thienopyrimidine-2,4-dione derivatives and intermediates thereof |
US4725599A (en) * | 1986-09-08 | 1988-02-16 | Pfizer Inc. | Heterocyclic ring fused pyrimidine-4 (3H)-ones as anticoccidial agents |
US4797486A (en) * | 1986-09-08 | 1989-01-10 | Pfizer Inc. | Heterocyclic ring fused pyrimidine-4(3H)-ones as anticoccidial agents |
EP0276057B1 (en) * | 1987-01-21 | 1994-03-09 | Merck & Co. Inc. | Piperazinylpyrimidines as beta-adrenergic receptor blocking agents |
US4871739A (en) * | 1987-01-21 | 1989-10-03 | Merck & Co., Inc. | Substituted 6H-7,8-dihydrothiapyrano(3,2-D)-pyrimidines as hyopglycemic agents |
US4889856A (en) * | 1987-08-31 | 1989-12-26 | Merck & Co., Inc. | 7,8-dihydro-4-(1-pierazinyl)-6H-thiopyrano-[3,2-d] pyrimidines as β-blockers |
US4994464A (en) * | 1987-08-31 | 1991-02-19 | Merck & Co., Inc. | Piperazinylpyrimidines as β-adrenergic receptor blockers |
US6232320B1 (en) | 1998-06-04 | 2001-05-15 | Abbott Laboratories | Cell adhesion-inhibiting antiinflammatory compounds |
US6458798B1 (en) | 1998-08-27 | 2002-10-01 | Sumitomo Pharmaceuticals Company, Limited | Bicyclic pyrimidine compounds and therapeutic use thereof |
WO2000042025A1 (fr) * | 1999-01-14 | 2000-07-20 | Meiji Seika Kaisha, Ltd. | Inhibiteurs de poly(adp-ribose) polymerase consistant en des derives de pyrimidine |
CN1894222A (zh) * | 2003-08-05 | 2007-01-10 | 沃泰克斯药物股份有限公司 | 作为电压门控离子通道抑制剂的稠合嘧啶化合物 |
TW200621257A (en) * | 2004-10-20 | 2006-07-01 | Astellas Pharma Inc | Pyrimidine derivative fused with nonaromatic ring |
PL1874781T3 (pl) * | 2006-04-19 | 2009-12-31 | Boehringer Ingelheim Int | Dihydrotienopirymidyny do leczenia chorób zapalnych |
EP1847543A1 (de) | 2006-04-19 | 2007-10-24 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dihydrothienopyrimidine zur Behandlung von entzündlichen Erkrankungen |
DK2205608T3 (da) * | 2007-10-18 | 2013-07-01 | Boehringer Ingelheim Int | Fremstilling af dihydrothieno[3,2-d]pyrimidiner og intermediære anvendt deri |
CA2702518A1 (en) | 2007-10-19 | 2009-04-23 | Boehringer Ingelheim International Gmbh | New piperazino-dihydrothienopyrimidine derivatives |
NZ585348A (en) | 2007-10-19 | 2012-02-24 | Boehringer Ingelheim Int | Heterocycle-substituted piperazino-dihydrothienopyrimidines |
PL2610258T3 (pl) | 2007-10-19 | 2015-02-27 | Boehringer Ingelheim Int | Podstawione piperydyno-dihydrotienopirymidyny |
NZ588484A (en) * | 2008-05-13 | 2012-06-29 | Boehringer Ingelheim Int | Synthesis of dihydrothieno[3,2-d]pyrimidine diols and similar pyrimidine diols |
US20130059866A1 (en) | 2011-08-24 | 2013-03-07 | Boehringer Ingelheim International Gmbh | Novel piperidino-dihydrothienopyrimidine sulfoxides and their use for treating copd and asthma |
US9802954B2 (en) | 2011-08-24 | 2017-10-31 | Boehringer Ingelheim International Gmbh | Piperidino-dihydrothienopyrimidine sulfoxides and their use for treating COPD and asthma |
WO2014124860A1 (en) | 2013-02-14 | 2014-08-21 | Boehringer Ingelheim International Gmbh | Specific pde4b-inhibitors for the treatment of diabetes mellitus |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB617435A (en) * | 1945-08-10 | 1949-02-07 | Lederle Lab Inc | Improvements in or relating to tetrahydro thieno uracils and method of preparing same |
US2792394A (en) * | 1954-01-25 | 1957-05-14 | Phillips Petroleum Co | Preparation of sulfenyl dithiocarbamates |
NL226623A (es) * | 1954-10-05 | |||
US2937118A (en) * | 1956-06-27 | 1960-05-17 | Raschig Gmbh Dr F | Aminopyridine compositions |
US3063902A (en) * | 1961-01-18 | 1962-11-13 | Irwin Neisler & Co | Analgesic aralkyl-pyridines |
US3244594A (en) * | 1962-01-12 | 1966-04-05 | Egyt Gyogyszervegyeszeti Gyar | 1, 6-bis-(beta-chloro-ethyl-amino)-1, 6-deoxy-d-mannitol heparinate |
-
1962
- 1962-07-04 DE DE19621470336 patent/DE1470336A1/de active Pending
-
1963
- 1963-06-17 US US288491A patent/US3272811A/en not_active Expired - Lifetime
- 1963-07-02 GB GB26221/63A patent/GB1048986A/en not_active Expired
-
1964
- 1964-06-08 US US373564A patent/US3318881A/en not_active Expired - Lifetime
- 1964-06-08 US US373565A patent/US3318883A/en not_active Expired - Lifetime
- 1964-06-16 ES ES0301102A patent/ES301102A1/es not_active Expired
-
1965
- 1965-03-31 NL NL6504085A patent/NL6504085A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US3272811A (en) | 1966-09-13 |
DE1470336A1 (de) | 1969-03-20 |
NL6504085A (es) | 1966-10-03 |
US3318883A (en) | 1967-05-09 |
US3318881A (en) | 1967-05-09 |
GB1048986A (en) | 1966-11-23 |
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