ES2965961T3 - Uso de inhibidores selectivos de INOS para el tratamiento de aneurismas de la aorta torácica (TAA) en un sujeto - Google Patents
Uso de inhibidores selectivos de INOS para el tratamiento de aneurismas de la aorta torácica (TAA) en un sujeto Download PDFInfo
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- ES2965961T3 ES2965961T3 ES16826369T ES16826369T ES2965961T3 ES 2965961 T3 ES2965961 T3 ES 2965961T3 ES 16826369 T ES16826369 T ES 16826369T ES 16826369 T ES16826369 T ES 16826369T ES 2965961 T3 ES2965961 T3 ES 2965961T3
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- 229940074404 sodium succinate Drugs 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
- C12N9/0073—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13
- C12N9/0075—Nitric-oxide synthase (1.14.13.39)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/13—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
- C12Y114/13039—Nitric-oxide synthase (NADPH dependent) (1.14.13.39)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96402—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals
- G01N2333/96405—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general
- G01N2333/96408—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from non-mammals in general with EC number
- G01N2333/96419—Metalloendopeptidases (3.4.24)
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/329—Diseases of the aorta or its branches, e.g. aneurysms, aortic dissection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Biochemistry (AREA)
- Zoology (AREA)
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- General Physics & Mathematics (AREA)
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- Cell Biology (AREA)
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- Veterinary Medicine (AREA)
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- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
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- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16382103 | 2016-03-07 | ||
| PCT/EP2016/082925 WO2017153023A1 (en) | 2016-03-07 | 2016-12-30 | In vitro method for identifying thoracic aortic aneurysms (taa) in a subject |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2965961T3 true ES2965961T3 (es) | 2024-04-17 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| ES16826369T Active ES2965961T3 (es) | 2016-03-07 | 2016-12-30 | Uso de inhibidores selectivos de INOS para el tratamiento de aneurismas de la aorta torácica (TAA) en un sujeto |
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| Country | Link |
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| US (2) | US10907135B2 (https=) |
| EP (1) | EP3427061B1 (https=) |
| JP (1) | JP7057976B2 (https=) |
| AU (1) | AU2016396401B2 (https=) |
| BR (1) | BR112018068045A2 (https=) |
| CA (1) | CA3017042C (https=) |
| ES (1) | ES2965961T3 (https=) |
| WO (1) | WO2017153023A1 (https=) |
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| ES2555790B1 (es) | 2014-06-05 | 2016-10-13 | Consejo Superior De Investigaciones Científicas (Csic) | Método de obtención de un array de micropartículas planares con multiplexado molecular superficial, array obtenido y su uso |
| WO2016123163A2 (en) | 2015-01-27 | 2016-08-04 | Kardiatonos, Inc. | Biomarkers of vascular disease |
| EP3384043B1 (en) | 2015-12-01 | 2020-02-19 | Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) | Method for diagnosing cardiomyopathies |
| WO2019101993A1 (en) | 2017-11-24 | 2019-05-31 | Consejo Superior De Investigaciones Científicas (Csic) | A modified brucella vaccine strain for the treatment of brucellosis |
| EP3740592A4 (en) * | 2018-02-19 | 2021-10-06 | The General Hospital Corporation | METHODS AND COMPOSITIONS FOR THE TREATMENT OF VASCULAR DISEASE |
| US12313635B2 (en) | 2018-07-27 | 2025-05-27 | The Regents Of The University Of California | Biomarker for thoracic aortic aneurysm |
| EP4088118A1 (en) * | 2020-01-10 | 2022-11-16 | Deutsches Herzzentrum München des Freistaates Bayern Klinik an der Technischen Universität München | Diagnosis of an aortic dissection by detecting a specific biomarker in a blood sample |
| US20210318336A1 (en) * | 2020-04-09 | 2021-10-14 | The Trustees Of The University Of Pennsylvania | Methods for treating aortic aneurysm disease |
| WO2022219196A1 (en) * | 2021-04-16 | 2022-10-20 | Centro Nacional De Investigaciones Cardiovasculares Carlos Iii (F.S.P.) | Method for the diagnosis, prognosis and/or treatment of thoracic aortic aneurysm |
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| US20030109522A1 (en) * | 2001-09-24 | 2003-06-12 | Manning Pamela T. | Ophthalmologic treatment methods using selective iNOS inhibitors |
| WO2014004889A2 (en) * | 2012-06-27 | 2014-01-03 | Musc Foundation For Research Development | Plasma analytes predict diagnosis and prognosis of thoracic aortic aneurysm |
| ES2555790B1 (es) | 2014-06-05 | 2016-10-13 | Consejo Superior De Investigaciones Científicas (Csic) | Método de obtención de un array de micropartículas planares con multiplexado molecular superficial, array obtenido y su uso |
| ES2612340B1 (es) | 2015-10-27 | 2018-03-09 | Consejo Superior De Investigaciones Científicas (Csic) | Sensor, aparato y procedimiento para la determinación de la concentración de solutos en disoluciones |
| EP3384043B1 (en) | 2015-12-01 | 2020-02-19 | Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) | Method for diagnosing cardiomyopathies |
| CN109843312A (zh) | 2016-04-29 | 2019-06-04 | 马德里自治大学 | 用作癌症或免疫失调患者的免疫治疗增效剂或佐剂的包含携带生物活性化合物的脂质体系的制剂 |
| WO2017198717A1 (en) | 2016-05-18 | 2017-11-23 | Consejo Superior De Investigaciones Científicas | Fusion proteins comprising an aldolase enzyme joined to a maltose binding protein |
| EP3681515A1 (en) | 2017-09-15 | 2020-07-22 | Fundación para la Investigación Biomédica del Hospital Universitario de la Paz (FIBHULP) | Mafg as a potential therapeutic target to restore chemosensitivity in platinum-resistant cancer cells |
| EP3703756B1 (en) | 2017-11-02 | 2022-04-20 | Consejo Superior de Investigaciones Científicas (CSIC) | Use of statins in overcoming resistance to beta-lactam antibiotics in bacterial species synthetizing isoprenoids using the mevalonate synthetic pathway |
| WO2019101993A1 (en) | 2017-11-24 | 2019-05-31 | Consejo Superior De Investigaciones Científicas (Csic) | A modified brucella vaccine strain for the treatment of brucellosis |
| US20210186989A1 (en) | 2018-06-06 | 2021-06-24 | Centro Nacional De Investigaciones Cardiovasculares Carlos Iii | Enhanced trained immunity in myeloid cells by ship-1 inhibition |
| JP7260341B2 (ja) | 2019-03-06 | 2023-04-18 | スタンレー電気株式会社 | 車両用灯具の制御装置、車両用灯具の制御方法、車両用灯具システム |
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2016
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2020
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Also Published As
| Publication number | Publication date |
|---|---|
| AU2016396401A1 (en) | 2018-10-25 |
| WO2017153023A1 (en) | 2017-09-14 |
| AU2016396401B2 (en) | 2023-07-13 |
| BR112018068045A2 (pt) | 2019-01-08 |
| JP2019510081A (ja) | 2019-04-11 |
| US12163161B2 (en) | 2024-12-10 |
| CA3017042A1 (en) | 2017-09-14 |
| CA3017042C (en) | 2024-02-20 |
| US10907135B2 (en) | 2021-02-02 |
| EP3427061A1 (en) | 2019-01-16 |
| JP7057976B2 (ja) | 2022-04-21 |
| US20190112582A1 (en) | 2019-04-18 |
| EP3427061C0 (en) | 2023-12-06 |
| US20210363501A1 (en) | 2021-11-25 |
| EP3427061B1 (en) | 2023-12-06 |
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