ES2938957A1 - Formulation of a nutritional supplement for animals rich in fatty acids without the use of technological additives (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Formulation of a nutritional supplement for animals rich in fatty acids without the use of technological additives. The present invention describes the use of Ocimum basilicum seed and other natural plant components in the formulation of a food supplement for pets without the use of technological additives, where the objective is to improve the quality of life of animals. providing said formulation useful bioactive elements intended to prevent the appearance of different health problems in animals. (Machine-translation by Google Translate, not legally binding)

Description

DESCRIPTION

Formulation of a nutritional supplement for animals rich in fatty acids without the use of technological additives

TECHNIQUE SECTOR

The present invention refers to the sector of food products for domestic or companion animals. Specifically, the present invention provides a food formulation rich in fatty acids without the use of additives.

BACKGROUND OF THE INVENTION

It is evidence that human well-being can be highly influenced by the environment, especially in those people who enjoy companion animals. The health and quality of life of pets has become an important concern in developed societies due to the repercussions that they can have on the emotional balance of their owners. It is, therefore, of interest to have means that improve the health and quality of life of companion animals.

In human society, the dog has historically been the animal that has been closest to it, not only as a company but also involved in such important tasks as guide dogs for blind people or its valued collaboration with rescue professionals. and security forces. Just as health care, and especially nutritional quality, has played a priority role in well-being and has fostered notable progress in life expectancy in the human species, it is also possible to make this situation a reality for our faithful canine companions.

As is the case with humans, pets can enjoy a more adequate diet aimed at preventing health problems, especially those derived from lifestyle, or at improving physiological conditions that the inexorable passage of time has deteriorated. The object of This invention is precisely to provide a nutritional formulation that helps to improve these situations both in healthy dogs and in those suffering from a pathological problem.

Nutrition, as a driving tool for improving the quality of life of animals, can be optimized with the incorporation of food supplements (functional foods and nutraceuticals). Despite the advances that have been made, there is still a need to develop compositions and methods that improve different physiological aspects, particularly during the reproductive season, growth and development, convalescent situations and, particularly, as happens in human beings. humans, in the aging phase, although the use of these food products can be useful for the treatment and/or prevention of situations of deterioration throughout any moment of the animal's life.

Such treatments could be beneficial to improve the general quality of life of companion animals and could lead to greater owner satisfaction by improving the bond between the owner and the animal, seeing the former also benefit from the enjoyment of the company. of your favorite animal for longer and in better living conditions.

Document US 2006/0166935 A1 refers to a composition of fatty acids for use in medicinal products, as well as in food products and supplements, for the treatment and/or prevention of diseases related to amyloids, such as Alzheimer's and / or cognitive dysfunction.

EP 3058942 refers to compositions comprising unsaturated fatty acids and nitric oxide releasing compounds and use thereof for the enhancement of cognitive and related functions.

Document ES 2310757 T3 refers to the use of compounds with omega-3 fatty acids for the treatment and/or prevention of canine osteoarthritis, one of the typical conditions of dogs throughout their lives.

The document WO11018547 refers to a probiotic preparation for the prevention or treatment of canine gastrointestinal disorders.

EP 2493491 refers to compositions that include ginger to ameliorate or prevent inflammatory conditions in compound cats and dogs.

EXPLANATION OF THE INVENTION

Unless otherwise defined, all technical and scientific terms, and any acronyms used herein have the same meanings as those commonly understood by one skilled in the art in the field of the invention. Although any compositions, methods, articles of manufacture, or other means or materials similar or equivalent to those described herein may be used in the practice of the present invention, preferred compositions, methods, articles of manufacture, or other means or materials are described herein. document.

One of the main concerns related to the health and well-being of companion animals focuses on food and therefore nutrition. It is, therefore, an important objective to have new foods or components that are integrated into them and provide a high nutritional value. In this sense, there is a growing interest in foods, nutritional elements and new substances that are of natural origin and that can be obtained from renewable raw materials. The plant world offers a wide range of functional compounds available for use in pet food with the aim of improving animal nutrition and, therefore, their quality of life. There are unknown plants in the animal feed field and their potential effects, and many new application areas for more well-known ones containing already used nutrients and bioactive substances are always surprising. In addition, some plant elements can not only provide a notable beneficial functionality in the health of the animal, but could constitute a component with a structural function in the formation of the food matrix.

Therefore, an object of the present invention is to provide natural compositions, without additives, for use in feeding breeding animals. company.

In this document, methods are also described for the prevention of different common health problems in pets (dogs) fundamentally associated with natural physiological processes such as growth, development and aging of the animal.

In this document, the preparation of the food matrix that supports the composition of the present invention and facilitates the combination of other useful ingredients for improving the quality of life of an animal is also described.

This is achieved through the use of innovative compositions based on seeds and plant extracts that contain nutritional and/or functional compounds such as unsaturated fatty acids and elements of a different nature such as probiotic microorganisms, polyphenols, antioxidants and other substances, all of natural origin. , capable of producing a food complement that can prevent health problems and improve the quality of life of the animal, being able to extend its life expectancy.

The compositions comprise the formation of a food matrix formed from different vegetable seeds rich in unsaturated fatty acids, among which the one from the species Ocimum basilicum is necessary since it provides a high content of a-linolenic acid (0-3). and an essential technological component for the formation of the food matrix that contains the rest of the ingredients, this material is the mucilage contained in the seed. Both ingredients are the basis of the food supplement and provide functional and structural value to the formulation. The proportion by weight with respect to the total of the formula, of this seed ranges between 50 and 85%, the rest of the components being variable in terms of type and quantities, although the integration of Cucurbita maxima and Coriandrum sativum seeds is preferred, rich in in linoleic (0-6) and oleic (0-9) acid, with proportions of between 10 and 20% of each with respect to the total weight for the realization of the base formulation (matrix) to which different components are added in order to to modulate the functionality of the final product.

The food matrix obtained has a functional nutritional value coming from the balance of its novel composition in unsaturated fatty acids, optimized for its use in the nutritional supplementation of dogs, which in itself already makes it a nutritional supplement for all purposes and also is a matrix obtained by extrusion in which the Ocimum basilicum mucilage performs an important technological function (texturization) since its use avoids the addition of other technological ingredients and additives that would have been necessary to provide the necessary texture to the extruded matrix. This invention represents an important technological advance and a notable industrial novelty as it is possible to have animal feed without the need to use texturizing carbohydrates and other additives. In the pharmaceutical and food industry, it can be widely used as adjuvants in numerous preparations, competing with synthetic polysaccharides, as they are generally inert, less toxic, and expensive. All this provides suitable characteristics for the delivery of drugs and food supplements, giving rise to stable and easily administrable formulations.

In addition, the mucilage has an added functional capacity, since it is a hydrocolloid, substances that have beneficial effects mainly due to their ability to retain water and their fermentation by intestinal bacteria. These properties corroborate the functional activity of these compounds as hypocholesterolemic, hypoglycemic and demulcent among others. Apart from their potential prebiotic effect, which gives them an important role in the prevention and/or treatment of some pathologies.

Therefore, the present invention would come, on the one hand, to improve the nutritional quality of the animals, taking into account that the formulation of the matrix is itself useful for this purpose since it contains a composition of unsaturated fatty acids optimized for Its use in dogs since the basic diet of these usually has certain difficulties to achieve the necessary levels of these nutrients or, if it provides them, these usually come from foods of animal origin (eg salmon oil).

In the case of this invention, the elements used to promote unsaturated fatty acids are exclusively of vegetable origin, also covering an existing gap in the demand for specialized food products. for pets without the use of animal components by pet owners.

On the other hand, with the use of Ocimum basilicum mucilage, of absolutely natural origin, the use of additives, texturizing agents and other elements of artificial origin used in pharmaceutical and food technology is limited in the preparation of the formulation, and solves the problem of the artificiality of the final product making it more natural and with less risk of toxicity, more suitable for animal health.

PREFERRED EMBODIMENT OF THE INVENTION

In one aspect, the invention provides compositions for use in the formulation of a nutritional supplement consisting of a food matrix obtained by extruding a mixture of different seed meals in certain proportions. Specifically, the seed of Ocimum basilicum must be used as an essential element in a proportion ranging between 50 and 85% with the intention of obtaining a final product that offers a wealth of Q-3 fatty acids (a-linolenic acid). and also constitutes a technological element for the realization of the extruded matrix. The mixture in question is completed with the contribution of seed flour in appropriate proportions, between 10% and 20% for each one, chosen from among Cucurbita maxima, Cucurbita pepo, Coriandrum sativum, Cucumis sativum, Nigella sativa, Solanum melongena, Solanum lycopersicum, Linum usitatissimum, Salvia hispánica, Cannabis sativa, Sesamum indicum, Brassica napus, Helianthus annuus, Papaver somniferum, Papaver rhoeas and Vitis vinifera.

For the correct elaboration of the matrix, the use of Ocimum basilicum seed in the appropriate proportion is preferably required. For which the virgin oil must be extracted from the seed previously. The cake obtained from the extraction is ground into flour and mixed in the preferred proportion with the other flours and a quantity of oil extracted from the Ocimum basilicum seed, between 30 and 60%. The entire mixture is subjected to an extrusion process, obtaining a product to which oil obtained from the seed of Ocimum basilicum is added. once cooled, by spraying in a proportion between 30 and 60%. Once dry, the result obtained constitutes the stable food matrix that contains an optimized mixture of unsaturated fatty acids as a nutritional functional element for dogs.

The composition of the food matrix inherently comprises the mucilage of the Ocimum basilicum seed, the flour of this seed, which is the fundamental ingredient. The intervention of the mucilage is necessary for the correct formation of the extruded product, but it also provides a functional effect as a prebiotic, understanding this as the effect caused by an indigestible food ingredient, which beneficially influences the health status of the host by stimulating selective growth and/or activity of intestinal microbiota. Prebiotics include fructooligosaccharides, xylooligosaccharides, galactooligosaccharides, mannooligosaccharides, gums, pectins, and mucilage. They are soluble fermentable fibers that have been previously described as providing a benefit to the immune system and may enhance the growth of probiotics within the intestine. Therefore, its presence in the proposed formulation could help to intensify the benefit provided by the present invention to the immune system of an animal.

In general, prebiotics are administered in amounts sufficient to positively stimulate the healthy microbiota of the gut and encourage the reproduction of these favorable bacteria. Typical amounts are from about 1 to about 10 grams per serving or from about 5% to about 40% of the recommended daily dietary fiber for an animal.

In this case, the prebiotic is found naturally in the fundamental ingredient of the formulation, since it is found in the external integuments of the Ocimum basilicum seeds, unlike those used in other formulations that need to apply or integrate these components in a natural way. artificial by spraying or pulverization, and have the property of swelling with water, giving rise to gels that can fulfill various functions in the animal's digestive tract; have a potential mechanical satiating effect, helping to reduce the animal's appetite, an important fact when its physical activity is decreased, something quite common in dogs that act as pets, especially when They live with humans in their homes. In addition, they cause an increase in the fecal bolus that stimulates peristalsis, improving intestinal transit in animals, something of interest when the animal's diet is not the most adequate.

It has been observed that the ingestion of mucilages produces a notable decrease in the absorption of fats and sugars, a fact of capital importance in the maintenance of the health of pets, to which must be added the limiting effect of the absorption of bile salts, which produces a decrease in circulating values of cholesterol in the animal. In the case of sugars, it causes them to be slowly absorbed, leading to a decrease in insulin secretion, thus preventing the storage of fatty acids in adipocytes, helping to prevent obesity, which is of great importance in animals with limited activity and greater.

In one embodiment, the proposed food composition may comprise any of a variety of ingredients or combinations thereof selected for their contributions to the overall composition. Thus, a food expert can choose between natural ingredients or components (eg, plants or plant derivatives, fungi or fungus derivatives, and microorganisms or microorganism derivatives).

Those skilled in the art will also appreciate that, in formulating the food compositions of the invention, the formulation may vary slightly such that variation from batch to batch can be taken into account by the formulator in the analysis of certain ingredients. Therefore, a given food composition or formulation may vary slightly from batch to batch, from plant to plant, or even from season to season, mainly depending on plant origin and variability, as well as its production system. production. Despite such variation of the specific ingredients selected to make a particular batch of a food formulation, the nutritional and/or active component composition may remain constant or at least substantially constant, for example, according to the label claim, as a guarantee of a minimum or maximum percentage of a particular component.

In other embodiments, the compositions of the invention comprise said Food matrix made up of the selected mixture of extruded seed meals to which other components can be added whose purpose is to modulate the functionality of the formulation to adapt it to the prevention of potential problems or to improve the health of the animal. Thus, in some embodiments, ingredients can be added that we classify as probiotics whose mission is to improve some physiological characteristic of the animal, preferably the immune and digestive functions.

Probiotic bacteria are believed to positively influence the immune response by improving the microbial balance in the intestine, which leads to enhanced antibody production and phagocytic activity of leukocytes. Probiotics enhance cellular immune system responses and may be useful as a dietary supplement to boost natural immunity in otherwise healthy animals.

Probiotics include many types of bacteria, but are generally selected from those species that have shown beneficial activity. The probiotics used can be specific to the animals to which they are directed or, as is usually done, bacterial strains known for their probiotic activity from other animals and more commonly from the human species are incorporated.

The person skilled in the art determines the amount of probiotics to be administered to the animal based on the type and nature of the probiotic and the type and nature of the animal, for example, age, weight, general state of health, sex, the degree of microbial depletion, the presence of harmful bacteria, and the animal's diet. In general, probiotics are administered to the animal in amounts from about 1 to about 20 billion colony-forming units (CFUs) per day for the maintenance of healthy gut microbiota, preferably from about 10 million to about 10 billion live bacteria. per day. Dietary supplements can be formulated to contain probiotics in the range from about 105 to about 1010 colony forming units (CFU) per gram of product, although higher concentrations of probiotics can be supplied.

The probiotics may be present in the formulation as an ingredient. They can be prokaryotes, eukaryotes or archaebacteria. Examples of suitable probiotics include yeasts such as Saccharomyces, Debaromyces, Candida, Pichia and Torulopsis, molds such as Aspergillus, Rhizopus, Mucor, and Penicillium and Torulopsis, and bacteria such as the genera Bifidobacterium, Bacteroides, Clostridium, Fusobacterium, Melissococcus, Propionibacterium, Streptococcus, Enterococcus, Lactococcus, Staphylococcus, Peptostrepococcus, Bacillus, Pediococcus, Micrococcus, Leuconostoc, Weissella, Aerococcus, Oenococcus, and Lactobacillus.

In a preferred embodiment, the food formulation is made up of the aforementioned rich and balanced matrix in unsaturated fatty acids to which are added at least one probiotic strain chosen from Enterococcus faecium, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus plantarum, Bifidobacterium bifidum, Bifidobacterium animalis, Bifidobacterium pseudolongum, Bifidobacterium lactis, Bifidobacterium breve, Streptococcus thermophilus, Pediococcus acidolactis, Bacillus coagulans, Aerococcus urinaeequi/viridans, Lactococcus lactis, Saccharomyces cerevisiae, Sa ccharomyces kefir and Candida kluyveromyces.

The compositions and dietary supplements derived from this invention may be specially formulated for the intended recipients or consumers, such as adult animals or older or younger animals. For example, a composition adapted to puppies or kittens or adapted to active, pregnant, lactating or aging animals can be prepared. In general, specialized compositions will comprise suitable nutritional requirements for animals at different stages of development or age.

In other embodiments, the compositions of the invention comprise the aforementioned food matrix made from seeds with the balanced composition of fatty acids to which natural substances such as minerals, vitamins, proteins, amino acids, fibers and natural preservatives obtained from vegetables, normally using parts of plants or extracts rich in these elements. Non-limiting examples of minerals include calcium, phosphorous, potassium, sodium, iron, chloride, boron, copper, zinc, magnesium, manganese, iodine, selenium, and the like, and various salts thereof. Non-limiting examples of vitamins include provitamin A, various B vitamins, for example, niacin, pantothenic acid, folic acid, biotin, vitamin D and vitamin K. Proposed formulations may also comprise carotenoids such as alpha-carotene, lycopene, lutein and zeaxanthin. All from vegetables with the aim of improving some physiological function in the receiving animal, thus the different selection of these functional elements would lead to obtaining a series of formulations adapted to certain needs.

In a preferred embodiment, the food matrix can be used, to which vegetable parts and/or natural extracts thereof are added, from Murraya koenigii leaves, Curcuma longa root, Moringa oleifera leaves, Ziziphus jujuba seed and fruit, root Withania somnifera, Argania espinosa fruit, Trigonella foenum-graecum seeds, Carica papaya fruit, Ananas comosus fruit, Beta vulgaris root, Grifola frondosa flour, Lentinula edodes flour, Ganoderma lucidum flour, Cordyceps sinensis flour and/or extracts of Psoralea corylifolia.

In another aspect, the present invention provides a method of promoting health or well-being in an animal comprising administering to an animal a health- or well-being-promoting amount of the food supplement proposed in the present invention. Some of the physiological actions that these preparations aim to achieve include strengthening the immune system, preventing cardiovascular problems, generalized inflammation, skin, hair and, in general, an improvement in the quality of life of the recipient animal.

Claims (12)

1a.- Use of Ocimum basilicum seeds as a functional and technological element in the formulation of animal feed. 2a.- Use of Ocimum basilicum seeds, according to claim 1a, in the formulation of food, food supplements and/or medicines for animals where the functional element is a-linolenic acid (0-3) contained in said seeds and where the technological element is the mucilage contained in said seeds. 3a.- Use of Ocimum basilicum seeds, according to claims ia and 2a, in which the proposed formulation comprises Ocimum basilicum seeds mixed with at least two other seeds rich in fatty acids. 4a.- Use of the seeds of Ocimum basilicum, according to claims ia to 3a, in which said formulation may also contain one or several modulating functional ingredients. 5.- Use of Ocimum basilicum seeds, according to claims ia to 3a, wherein said formulation contains a proportion of Ocimum basilicum seeds of between 50 and 85%, preferably 70%. 6a.- Use of the seeds of Ocimum basilicum, according to claims ia to 3a, in which the other seeds rich in fatty acids are selected from Cucurbita maxima, Cucurbita pepo, Coriandrum sativum, Cucumis sativum, Nigella sativa, Solanum melongena, Solanum lycopersicum , Linum usitatissimum, Salvia hispánica, Cannabis sativa, Sesamum indicum, Brassica napus, Helianthus annuus, Papaver somniferum, Papaver rhoeas and Vitis vinifera. 7th.- Use of Ocimum basilicum seeds, according to claim 6th, in which the seeds that form the proposed formulation are preferably Cucurbita maxima and Coriandrum sativum, with proportions of between 10 and 20%, preferably 15% for Cucurbita maxima , and 10 and 20%, preferably 15% of Coriandrum sativum with respect to the total weight. 8a.- Use of the seeds of Ocimum basilicum, according to claim 4a, in which the modulating functional ingredients are selected from Enterococcus faecium, Lactobacillus acidophilus, Lactobacillus bulgaricus, Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus plantarum, Bifidobacterium bifidum, Bifidobacterium animalis, Bifido bacteria pseudolongum, Bifidobacterium lactis, Bifidobacterium breve, Streptococcus thermophilus, Pediococcus acidolactis, Bacillus coagulans, Aerococcus urinaeequi/viridans, Lactococcus lactis, Saccharomyces cerevisiae, Saccharomyces kefir, Candida kluyveromyces, Murraya koenigi leaves i, Curcuma longa root, Moringa oleifera leaves, seed and Ziziphus jujuba fruit, Withania somnifera root, Argania espinosa fruit, Trigonella foenum-graecum seeds, Carica papaya fruit, Ananas comosus fruit, Beta vulgaris root, Grifola frondosa flour, Lentinula edodes flour, Ganoderma lucidum, Cordyceps sinensis flour, Psoralea corylifolia extracts and parts or extracts of Punica granatum. 9a.- A natural, solid formulation, without additives, comprising Ocimum basilicum seed flour accompanied by one or more ingredients selected from flours from seeds selected from Cucurbita maxima, Cucurbita pepo, Coriandrum sativum, Cucumis sativum, Nigella sativa, Solanum melongena, Solanum lycopersicum, Linum usitatissimum, Salvia hispánica, Cannabis sativa, Sesamum indicum, Brassica napus, Helianthus annuus, Papaver somniferum, Papaver rhoeas and Vitis vinifera and one or more additional ingredients selected from Enterococcus faecium, Lactobacillus acidophilus, Lactobacillus bul garicus, Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus plantarum, Bifidobacterium bifidum, Bifidobacterium animalis, Bifidobacterium pseudolongum Bifidobacterium lactis, Bifidobacterium breve, Streptococcus thermophilus, Pediococcus acidolactis, Bacillus coagulans, Aerococcus urinaeequi/vi ridans, Lactococcus lactis, Saccharomyces cerevisiae, Saccharomyces kefir, Candida kluyveromyces, leaves of Murraya koenigii, root of Curcuma longa, leaves of Moringa oleifera, seed and fruit of Ziziphus jujuba, root of Withania somnifera, fruit of Argania espinosa, seeds of Trigonella foenum-graecum, fruit of Carica papaya, fruit of Ananas comosus, root of Beta vulgaris, Grifola frondosa flour, Lentinula edodes flour, Ganoderma lucidum flour, Cordyceps sinensis flour, Psoralea corylifolia extracts and parts or extracts of Punica granatum; in which the amount of Ocimum basilicum seed meal is between 50 and 1 85%, preferably 70% by weight with respect to the total weight of the formulation and between 10 and 20%, preferably 15% of Cucurbita maxima flour and 10 and 20%, preferably 15% of Coriandrum sativum flour by weight with respect to the weight total of the formulation. 10.- Use of a formulation, according to claim 9, as food, food supplement and/or medicine for animals that contains a proportion of fatty acids Q-3 between 5 and 25%, preferably 17%, Q-6 between 5 and 20 %, preferably 10.25% and Q-9 between 5 and 20%, preferably 7.25%; and is intended to achieve an improvement in the quality of life of the animal. 11a.- A procedure for the preparation of a base matrix for the manufacture of food and/or food supplements made from Ocimum basilicum seeds where the extraction of the oil contained in them is required by mechanical processes, preferably at a temperature below 50 ° C although it could also be extracted using chemical solvents. The cake obtained is ground into flour and mixed with other flours according to claim 9, to which is added a proportion of the total oil extracted between 30 and 60%, preferably 46.5%, and is subsequently extruded without the need to add additives. technological since the mucilage contained in the Ocimun basilicum seed meal performs the necessary technological function. Once the extrusion has cooled, it is sprayed with a quantity of oil obtained from the seeds of Ocimum basilicum in a proportion of the total obtained from the extraction between 30 and 60%, preferably 53.5%. 12a.- Use of mucilage from Ocimun basilicum seeds as a technological agent in the manufacture of food products obtained by extrusion procedures.