ES2927500T3 - A device for stopping a vial, adapted to preserve substances that must be kept separate until their application and also adapted to collect the mixture obtained through a syringe - Google Patents

A device for stopping a vial, adapted to preserve substances that must be kept separate until their application and also adapted to collect the mixture obtained through a syringe Download PDF

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Publication number
ES2927500T3
ES2927500T3 ES19160847T ES19160847T ES2927500T3 ES 2927500 T3 ES2927500 T3 ES 2927500T3 ES 19160847 T ES19160847 T ES 19160847T ES 19160847 T ES19160847 T ES 19160847T ES 2927500 T3 ES2927500 T3 ES 2927500T3
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Prior art keywords
bottle
piston
membrane
container
substance
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ES19160847T
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Spanish (es)
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Alessio Nobbio
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Inge SpA
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Inge SpA
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/24Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • B65D51/28Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials
    • B65D51/2807Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container
    • B65D51/2814Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it
    • B65D51/2828Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it said element being a film or a foil
    • B65D51/2835Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it said element being a film or a foil ruptured by a sharp element, e.g. a cutter or a piercer
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00Closures not otherwise provided for
    • B65D51/002Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Basic Packing Technique (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Abstract

Dispositivo para tapar una botella de forma sustancialmente cilíndrica internamente hueca, que comprende una parte superior (21), que forma en ella un depósito (3) para mezclar una primera sustancia con una segunda sustancia presente en la botella, una parte inferior (22) provista de medios de fijación a la botella. La base del tanque tiene una película (31) soldada en un borde ubicado cerca de la unión de la parte superior con la parte inferior. El dispositivo comprende medios para romper la base del tanque que pueden ser accionados por presión y manualmente desde la parte superior de dicho dispositivo que comprende un pistón (4) capaz de deslizarse hacia abajo dentro de la parte superior hueca, provisto de al menos una punta de fractura (41).) en su extremo inferior, que durante el descenso del pistón perfora la película antes mencionada liberando el contenido del tanque en la botella. La parte superior del pistón (4) comprende una membrana (42) que puede ser perforada por una aguja de jeringa que cuando el propio pistón ha perforado el propio tanque permite que dicha aguja tome el contenido de la mezcla en la botella. (Traducción automática con Google Translate, sin valor legal)Device for covering a bottle with a substantially cylindrical shape, internally hollow, comprising an upper part (21), which forms a reservoir (3) in it to mix a first substance with a second substance present in the bottle, a lower part (22) provided with fixing means to the bottle. The base of the tank has a film (31) welded on one edge located near the junction of the top with the bottom. The device comprises means to break the base of the tank that can be actuated by pressure and manually from the upper part of said device comprising a piston (4) capable of sliding downwards inside the hollow upper part, provided with at least one point of fracture (41).) at its lower end, which during the descent of the piston pierces the aforementioned film, releasing the contents of the tank in the bottle. The upper part of the piston (4) comprises a membrane (42) that can be pierced by a syringe needle that, when the piston itself has pierced the tank itself, allows said needle to take the contents of the mixture in the bottle. (Automatic translation with Google Translate, without legal value)

Description

DESCRIPCIÓNDESCRIPTION

Un dispositivo para tapar un frasco, adaptado para conservar sustancias que deben mantenerse separadas hasta su aplicación y también adaptado para recoger la mezcla obtenida a través de una jeringaA device for stopping a vial, adapted to preserve substances that are to be kept separate until their application and also adapted to collect the mixture obtained through a syringe

La presente invención se refiere a un dispositivo para tapar una botella, adaptado para la conservación de sustancias, por ejemplo polvos o líquidos, para mantenerlas separadas hasta el momento de su utilización, cuando se mezclan entre sí.The present invention refers to a device for covering a bottle, adapted for the conservation of substances, for example powders or liquids, to keep them separated until the moment of their use, when they are mixed together.

Actualmente, existen en el mercado envases que permiten mantener separadas las sustancias contenidas en él hasta el momento de su utilización. Esta necesidad se presenta, por ejemplo, en el caso de la conservación de productos farmacéuticos que si se pusieran a la venta ya mezclados y listos para su uso, perderían su poder terapéutico en un corto período de tiempo.Currently, there are containers on the market that allow the substances contained in them to be kept separate until they are used. This need arises, for example, in the case of the conservation of pharmaceutical products that, if they were put on sale already mixed and ready for use, would lose their therapeutic power in a short period of time.

Dichos envases suelen estar provistos de un dispositivo para tapar la botella, que consiste en una cápsula en cuyo interior hay un recipiente cilíndrico para una primera sustancia, por ejemplo en polvo, que debe mezclarse con una segunda sustancia presente en la botella, por ejemplo una sustancia líquida. Dicha cápsula está también asociada a un elemento de rotura, cuya parte superior puede presionarse para que un vástago de dicho elemento penetre en el recipiente y para que el extremo inferior del vástago rompa la base inferior del recipiente cilíndrico a lo largo de, al menos, una parte del perímetro circular del recipiente cilíndrico. De este modo, la primera sustancia se libera en el interior de la botella formando la mezcla deseada con la segunda sustancia contenida en la botella.Said containers are usually provided with a device to cover the bottle, which consists of a capsule inside which there is a cylindrical container for a first substance, for example powder, which must be mixed with a second substance present in the bottle, for example a liquid substance. Said capsule is also associated with a breaking element, the upper part of which can be pressed so that a rod of said element penetrates the container and so that the lower end of the rod breaks the lower base of the cylindrical container along, at least, a part of the circular perimeter of the cylindrical container. In this way, the first substance is released inside the bottle, forming the desired mixture with the second substance contained in the bottle.

El perímetro de la base del depósito tiene una membrana que, ventajosamente, está provista de elementos de debilitamiento o fractura previa, los cuales facilitan su rotura.The perimeter of the base of the tank has a membrane that, advantageously, is provided with elements for weakening or prior fracture, which facilitate its breakage.

El dispositivo suele estar conectado a la botella a través de un acoplamiento roscado, de modo que la propia botella puede abrirse para utilizar el producto contenido en ella tras la formación de la mezcla. En ocasiones, la cápsula, el depósito y los medios de rotura están fabricados en una sola pieza. Además, la base del recipiente es una membrana de separación soldada al propio recipiente y está hecha de un material adaptado para impedir el paso del vapor de agua, desde el exterior al interior del recipiente y viceversa. Además, se conocen botellas adaptadas para contener medicamentos líquidos o en polvo que deben mezclarse con un líquido antes de su uso, los cuales deben tomarse a través de una jeringa. En estas botellas, la tapa está provista de una porción anular para engarzarla al cuello de la botella y de una porción central, por ejemplo de goma, que puede ser perforada por la aguja de la jeringa, evitando que se entre aire desde el exterior de la botella. En cualquier caso, la tapa en su conjunto está provista de medios de sellado en el cuello de la botella para la conservación de su contenido. En el caso de que el contenido en polvo deba mezclarse con un líquido, por ejemplo una solución fisiológica, normalmente dicho líquido se introduce por medio de la propia jeringa y después de haber agitado el frasco para mezclar los dos componentes, con la misma jeringa se toma el medicamento que se ha mezclado.The device is usually connected to the bottle via a threaded coupling, so that the bottle itself can be opened to use the product contained therein after the mixture has been formed. Sometimes the capsule, the reservoir and the breaking means are made in one piece. In addition, the base of the container is a separation membrane welded to the container itself and is made of a material adapted to prevent the passage of water vapor, from the outside to the inside of the container and vice versa. In addition, bottles adapted to contain liquid or powder medicines that must be mixed with a liquid before use, which must be taken through a syringe, are known. In these bottles, the cap is provided with an annular portion to be attached to the neck of the bottle and with a central portion, for example made of rubber, which can be pierced by the syringe needle, preventing air from entering from outside the bottle. the bottle. In any case, the lid as a whole is provided with sealing means on the neck of the bottle to preserve its contents. In the event that the powder content must be mixed with a liquid, for example a physiological solution, normally said liquid is introduced through the syringe itself and after having shaken the bottle to mix the two components, with the same syringe take the medicine that has been mixed.

La presente invención propone un dispositivo para tapar una botella que sea al mismo tiempo capaz de mantener separadas dos sustancias hasta su aplicación y capaz de contener la mezcla obtenida para tomarse por medio de una jeringa. En el documento WO2016/038357 se divulga un dispositivo de este tipo en el estado de la técnica. The present invention proposes a device for closing a bottle that is at the same time capable of keeping two substances separated until their application and capable of containing the mixture obtained to be taken by means of a syringe. Document WO2016/038357 discloses a device of this type in the state of the art.

La presente invención se refiere a un dispositivo para tapar una botella que tiene las características de la reivindicación 1 adjunta.The present invention relates to a bottle capping device having the features of attached claim 1.

Las características y ventajas del dispositivo para tapar una botella según la presente invención quedarán más claras a partir de la siguiente descripción, dada a modo de ejemplo y sin propósitos limitativos, refiriéndose a los dibujos esquemáticos adjuntos, en los que:The characteristics and advantages of the device for corking a bottle according to the present invention will become clearer from the following description, given by way of example and without limitative purposes, referring to the attached schematic drawings, in which:

• la figura 1 muestra una vista lateral de un dispositivo para tapar una botella según la invención;• figure 1 shows a side view of a device for capping a bottle according to the invention;

• la figura 2 muestra una sección a lo largo de la línea A-A de la figura 1 del dispositivo según la presente invención;• figure 2 shows a section along the line A-A of figure 1 of the device according to the present invention;

• la figura 3 ilustra una vista desde arriba del dispositivo según la presente invención.• Figure 3 illustrates a top view of the device according to the present invention.

Con referencia a las figuras citadas, se ilustra una realización del dispositivo de tapado, la cual está asociada a una botella, por ejemplo de forma cilíndrica (que no se muestra). La presente invención puede aplicarse de manera equivalente a botellas que tienen formas diferentes. Es más, en el caso específico en el que el dispositivo de tapado está roscado internamente y, por consiguiente, se enrosca en el recipiente. En otra realización, el dispositivo de cierre podría aplicarse sobre el envase por presión o de formas equivalentes que aseguren el cierre hermético del cierre.With reference to the cited figures, an embodiment of the capping device is illustrated, which is associated with a bottle, for example cylindrical in shape (not shown). The present invention can be equivalently applied to bottles having different shapes. Moreover, in the specific case where the capping device is internally threaded and therefore screws onto the container. In another embodiment, the closure device could be applied to the container by pressure or in equivalent ways that ensure the sealing of the closure.

En detalle, el dispositivo de tapado 2 tiene preferiblemente una forma cilíndrica, hueca internamente, con una porción superior 21, que forma un recipiente 3 en su interior para una primera sustancia que se mezclará con una segunda sustancia presente en la botella. In detail, the capping device 2 preferably has a cylindrical shape, internally hollow, with an upper portion 21, which forms a container 3 inside it for a first substance to be mixed with a second substance present in the bottle.

Dicha primera y segunda sustancia pueden estar formadas, por ejemplo, por polvo, líquido, granulado u otras sustancias que se mezclen con el líquido. El dispositivo también comprende medios para romper la base del recipiente, que se pueden accionar por presión y manualmente desde la parte superior de dicho dispositivo.Said first and second substances can be formed, for example, by powder, liquid, granules or other substances that are mixed with the liquid. The device also comprises means to break the base of the container, which can be actuated by pressure and manually from the top of said device.

El dispositivo de tapado 2 comprende también una porción inferior 22 de mayor diámetro que el diámetro de la porción superior, provista de medios de fijación a la botella, como por ejemplo una rosca interna 221 o, alternativamente, medios de fijación a presión sobre el recipiente 2.The capping device 2 also comprises a lower portion 22 with a greater diameter than the diameter of the upper portion, provided with fixing means to the bottle, such as an internal thread 221 or, alternatively, fixing means by pressing on the container. 2.

Dicha porción inferior comprende eventualmente una junta de cierre anular 222 con la botella, del tipo de las presentes en las tapas de las bebidas que contienen las botellas de plástico.Said lower portion possibly includes an annular sealing joint 222 with the bottle, of the type present in the lids of beverages contained in plastic bottles.

La base del recipiente tiene una lámina 31 soldada en un borde situado cerca de la unión de la parte superior con la parte inferior.The base of the container has a sheet 31 welded on one edge near the junction of the top with the bottom.

Dicha película está, por ejemplo, termosoldada, soldada por inducción o pegada en dicho borde, y está hecha de un material plástico acoplado a una película de aluminio.Said film is, for example, heat-sealed, induction-welded or glued on said edge, and is made of a plastic material coupled to an aluminum film.

Dicha película, cuando el dispositivo de separación está cerrado sobre la botella, separa la primera sustancia que contiene el recipiente 3 de la segunda sustancia que contiene la botella.Said film, when the separation device is closed on the bottle, separates the first substance contained in the container 3 from the second substance contained in the bottle.

En el caso de que una de las dos sustancias sea líquida, la película impide un posible paso de vapor de agua a través de ella y, por lo tanto, da lugar a una premezcla no deseada entre las dos sustancias, la cual haría ineficaz el producto en el momento de su utilización.In the event that one of the two substances is liquid, the film prevents a possible passage of water vapor through it and, therefore, gives rise to an undesired premix between the two substances, which would make the treatment ineffective. product at the time of use.

Dichos medios de rotura del depósito están constituidos por un pistón 4 capaz de deslizarse hacia abajo en el interior de la porción superior hueca y está provisto de al menos una punta de fractura 41 en su extremo inferior, que durante el descenso del pistón perfora la película mencionada liberando el contenido del recipiente.Said means for breaking the deposit are constituted by a piston 4 capable of sliding downwards inside the hollow upper portion and is provided with at least one fracture tip 41 at its lower end, which during the descent of the piston pierces the film. mentioned releasing the contents of the container.

Ventajosamente, la porción inferior 22 comprende una pluralidad de nervaduras y/o rebajes dispuestos sustancialmente en sentido vertical, adaptados para facilitar la manipulación del dispositivo durante la operación de apertura y cierre del recipiente.Advantageously, the lower portion 22 comprises a plurality of ribs and/or recesses arranged substantially vertically, adapted to facilitate handling of the device during the opening and closing operation of the container.

Según la presente invención, la parte superior del pistón 4 comprende una membrana 42 que puede ser perforada por una aguja de jeringa que, cuando el propio pistón ha perforado el recipiente, permite que dicha aguja introduzca el contenido de la mezcla en la botella.According to the present invention, the upper part of the piston 4 comprises a membrane 42 that can be pierced by a syringe needle which, when the piston itself has pierced the container, allows said needle to introduce the contents of the mixture into the bottle.

Dicha membrana puede ser de goma, de plástico, en general de un material que garantice el cierre hermético y que se pueda perforar fácilmente.Said membrane can be made of rubber, of plastic, in general of a material that guarantees hermetic sealing and that can be easily pierced.

Dicha membrana ocupa una zona sustancialmente central de la parte superior del pistón. Además, tiene forma discoidal y está empotrada en un asiento conformado en la parte superior del pistón para no sobresalir con respecto a una corona circular que delimita dicho asiento. La membrana está moldeada junto con el pistón o con el dispositivo cuando este último está fabricado en una sola pieza. La membrana presenta en su zona central una porción cónica 43, preferentemente cóncava, que es la zona donde se inserta la aguja de la jeringa. De este modo, se facilita la penetración de la aguja incluso cuando esta es un tipo de aguja muy fina.Said membrane occupies a substantially central area of the upper part of the piston. In addition, it has a discoidal shape and is embedded in a seat formed in the upper part of the piston so as not to protrude from a circular crown that delimits said seat. The membrane is molded together with the piston or with the device when the latter is made in one piece. In its central area, the membrane has a conical portion 43, preferably concave, which is the area where the syringe needle is inserted. In this way, the penetration of the needle is facilitated even when it is a very fine type of needle.

El dispositivo según la presente invención funciona de la siguiente manera.The device according to the present invention works in the following way.

Cuando se desea mezclar las dos sustancias, basta con presionar el pistón del dispositivo. De este modo, esta última se ve obligada a descender hasta que la punta de fractura penetra en la membrana, provocando la rotura casi total de la membrana y haciendo que la primera sustancia contenida en el depósito caiga por gravedad en la botella entrando así en contacto con la segunda sustancia. Una vez mezcladas las sustancias, basta con introducir una aguja de jeringa en la membrana 42 y alcanzar la mezcla en la botella, puesto que la punta de fractura 41 ya ha abierto la película 31 y no hay más barreras entre la aguja y el interior de la botella. When you want to mix the two substances, just press the piston of the device. In this way, the latter is forced to descend until the fracture point penetrates the membrane, causing the almost complete rupture of the membrane and causing the first substance contained in the deposit to fall by gravity into the bottle, thus coming into contact with the second substance. Once the substances are mixed, it is enough to insert a syringe needle into the membrane 42 and reach the mixture in the bottle, since the fracture tip 41 has already opened the film 31 and there are no more barriers between the needle and the interior of the bottle.

Claims (5)

REIVINDICACIONES 1. Un dispositivo para tapar una botella con una forma interna sustancialmente cilindrica, que comprende1. A device for capping a bottle with a substantially cylindrical internal shape, comprising • una porción superior (21), que forma en su interior un recipiente (3) para una primera sustancia a mezclar con una segunda sustancia presente en la botella,• an upper portion (21), which forms a container (3) inside it for a first substance to be mixed with a second substance present in the bottle, • una porción inferior (22) provista de medios de fijación a la botella,• a lower portion (22) provided with fixing means to the bottle, • la base del recipiente, que tiene una lámina (31) soldada en un borde situado en las proximidades de la unión de la porción superior con la porción inferior,• the base of the container, which has a sheet (31) welded on one edge located near the junction of the upper portion with the lower portion, • medios para romper la base del recipiente, accionables por presión y manualmente desde la parte superior de dicho dispositivo, que comprenden un pistón (4) capaz de deslizarse hacia abajo en el interior de la porción superior hueca provisto de al menos una punta de fractura (41) en su extremo inferior, que durante el descenso del pistón perfora la pelicula mencionada liberando el contenido del depósito en la botella,• Means for breaking the base of the container, actuatable by pressure and manually from the upper part of said device, comprising a piston (4) capable of sliding downwards inside the hollow upper portion provided with at least one fracture point. (41) at its lower end, which during the descent of the piston pierces the aforementioned film, releasing the contents of the deposit in the bottle, • la parte superior del pistón (4) comprende una membrana (42) que se puede perforar con una aguja de jeringa, lo cual permite que dicha aguja tome el contenido de la mezcla de la botella cuando el pistón perfora el recipiente, caracterizado en cuanto a que dicha membrana es de forma discoidal y está empotrada en un asiento obtenido en la parte superior del pistón para no sobresalir con respecto a una corona circular que delimita dicho asiento, en el que la membrana está moldeada junto con el pistón o el dispositivo cuando este último está fabricado en una sola pieza.• the upper part of the piston (4) comprises a membrane (42) that can be pierced with a syringe needle, which allows said needle to take the contents of the mixture from the bottle when the piston pierces the container, characterized in that because said membrane is discoidal in shape and is embedded in a seat obtained in the upper part of the piston so as not to protrude from a circular crown that delimits said seat, in which the membrane is molded together with the piston or the device when the latter is made in one piece. 2. Un dispositivo según la reivindicación 1, en el que dicha membrana ocupa una zona sustancialmente central de la parte superior del pistón.A device according to claim 1, wherein said membrane occupies a substantially central area of the upper part of the piston. 3. Dispositivo según la reivindicación 1, en el que la membrana tiene una parte cónica (43) en la zona central, que es la zona en la que se va a introducir la aguja de la jeringa.Device according to claim 1, in which the membrane has a conical part (43) in the central area, which is the area into which the syringe needle is to be inserted. 4. Dispositivo según la reivindicación 1, en el que la parte cónica es cóncava.Device according to claim 1, in which the conical part is concave. 5. Dispositivo según la reivindicación 1, en el que dicha membrana puede ser de caucho, plástico, generalmente de un material que garantice el cierre hermético y sea fácil de perforar. Device according to claim 1, in which said membrane can be made of rubber, plastic, generally of a material that guarantees hermetic sealing and is easy to pierce.
ES19160847T 2018-03-06 2019-03-05 A device for stopping a vial, adapted to preserve substances that must be kept separate until their application and also adapted to collect the mixture obtained through a syringe Active ES2927500T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102018000003313A IT201800003313A1 (en) 2018-03-06 2018-03-06 Bottle capping device for storing substances to be kept separate until their application and for taking the mixture obtained by syringe.

Publications (1)

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ES2927500T3 true ES2927500T3 (en) 2022-11-07

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ES19160847T Active ES2927500T3 (en) 2018-03-06 2019-03-05 A device for stopping a vial, adapted to preserve substances that must be kept separate until their application and also adapted to collect the mixture obtained through a syringe

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EP (1) EP3536631B1 (en)
ES (1) ES2927500T3 (en)
IT (1) IT201800003313A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20210114086A (en) * 2020-03-09 2021-09-23 주식회사 태성산업 A airless type mixing container for two kinds of contents capable of exhausting the whole volume

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2495942A (en) * 1947-06-14 1950-01-31 William A Nosik Multiple chamber container
FR996181A (en) * 1949-08-13 1951-12-14 Device for mixing two products normally kept separate in the same container, without unblocking the latter
US3136440A (en) * 1963-06-25 1964-06-09 Becton Dickinson Co Self sealing pierceable stopper for sealed containers
US7951109B2 (en) * 2006-09-22 2011-05-31 Andeboh Holdings, Flp Liquid chamber cap with compartment for use with injectables
DE102011079031A1 (en) * 2011-07-12 2013-01-17 Algeta Asa liquid container
WO2013188703A1 (en) * 2012-06-13 2013-12-19 Py Daniel C Device with penetrable septum and closure needle
GB201415869D0 (en) * 2014-09-08 2014-10-22 Eulysis Uk Ltd Container And Closure

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EP3536631A1 (en) 2019-09-11
IT201800003313A1 (en) 2019-09-06

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