ES291954A1 - Method of elaboration a diacilcimarol (Machine-translation by Google Translate, not legally binding) - Google Patents

Method of elaboration a diacilcimarol (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES291954A1
ES291954A1 ES291954A ES291954A ES291954A1 ES 291954 A1 ES291954 A1 ES 291954A1 ES 291954 A ES291954 A ES 291954A ES 291954 A ES291954 A ES 291954A ES 291954 A1 ES291954 A1 ES 291954A1
Authority
ES
Spain
Prior art keywords
formula
translation
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES291954A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB37529/62A external-priority patent/GB1075251A/en
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES291954A1 publication Critical patent/ES291954A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J19/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 by a lactone ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Method of making a diacylcimarol of the formula I, characterized in that, in order to produce a drug for the treatment of heart failure, which has an oral therapeutic index higher than that of digoxin, a 4'-monoacrylocamimarol is acylated. formula II with an acylating agent of formula R1.CO.X or, when R1 is to be the same as R2, cimarol is acylated with an acylating agent of formula R2.CO.X; ** (See formula) ** in these formulas R1 is a hydrogen atom or an aliphatic radical having 1 to 3 carbon atoms, R2 is an aliphatic radical having 1 to 3 carbon atoms and X is a proton acceptor radical. (Machine-translation by Google Translate, not legally binding)
ES291954A 1962-10-04 1963-09-25 Method of elaboration a diacilcimarol (Machine-translation by Google Translate, not legally binding) Expired ES291954A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB37529/62A GB1075251A (en) 1962-10-04 1962-10-04 Cardenolide derivatives
GB3251163 1963-08-16
GB3251263 1963-08-16

Publications (1)

Publication Number Publication Date
ES291954A1 true ES291954A1 (en) 1963-11-01

Family

ID=27259055

Family Applications (1)

Application Number Title Priority Date Filing Date
ES291954A Expired ES291954A1 (en) 1962-10-04 1963-09-25 Method of elaboration a diacilcimarol (Machine-translation by Google Translate, not legally binding)

Country Status (10)

Country Link
BE (1) BE638140A (en)
CH (3) CH431510A (en)
DE (1) DE1593722C3 (en)
DK (3) DK111175B (en)
ES (1) ES291954A1 (en)
FI (2) FI40459B (en)
LU (1) LU44568A1 (en)
MC (1) MC436A1 (en)
NL (1) NL298322A (en)
SE (3) SE318272B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5897107A (en) * 1997-02-24 1999-04-27 Horton, Inc. Roller bushing assembly

Also Published As

Publication number Publication date
DE1593722C3 (en) 1974-11-07
DK111175B (en) 1968-06-24
CH433277A (en) 1967-04-15
NL298322A (en)
DE1593722A1 (en) 1970-12-03
FI41551B (en) 1969-09-01
DE1593722B2 (en) 1974-04-04
CH431510A (en) 1967-03-15
LU44568A1 (en) 1964-04-04
MC436A1 (en) 1964-07-06
BE638140A (en)
DK114831B (en) 1969-08-11
FI40459B (en) 1968-10-31
SE318272B (en) 1969-12-08
SE324151B (en) 1970-05-25
DK113499B (en) 1969-03-31
SE318560B (en) 1969-12-15
CH428721A (en) 1967-01-31

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