ES2881474T3 - Composiciones, métodos y kits para el diagnóstico de una neoplasia neuroendocrina gastroenteropancreática - Google Patents

Composiciones, métodos y kits para el diagnóstico de una neoplasia neuroendocrina gastroenteropancreática Download PDF

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Publication number
ES2881474T3
ES2881474T3 ES15771837T ES15771837T ES2881474T3 ES 2881474 T3 ES2881474 T3 ES 2881474T3 ES 15771837 T ES15771837 T ES 15771837T ES 15771837 T ES15771837 T ES 15771837T ES 2881474 T3 ES2881474 T3 ES 2881474T3
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nen
gep
expression
biomarkers
subject
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Spanish (es)
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Irvin Mark Modlin
Mark Kidd
Ignat Drozdov
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Clifton Life Sciences LLC
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Clifton Life Sciences LLC
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57557Immunoassay; Biospecific binding assay; Materials therefor for cancer of other specific parts of the body, e.g. brain
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2537/00Reactions characterised by the reaction format or use of a specific feature
    • C12Q2537/10Reactions characterised by the reaction format or use of a specific feature the purpose or use of
    • C12Q2537/143Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/107Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/112Disease subtyping, staging or classification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ES15771837T 2014-09-15 2015-09-15 Composiciones, métodos y kits para el diagnóstico de una neoplasia neuroendocrina gastroenteropancreática Active ES2881474T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462050465P 2014-09-15 2014-09-15
PCT/US2015/050274 WO2016044330A1 (en) 2014-09-15 2015-09-15 Compositions, methods and kits for diagnosis of a gastroenteropancreatic neuroendocrine neoplasm

Publications (1)

Publication Number Publication Date
ES2881474T3 true ES2881474T3 (es) 2021-11-29

Family

ID=54207775

Family Applications (2)

Application Number Title Priority Date Filing Date
ES15771837T Active ES2881474T3 (es) 2014-09-15 2015-09-15 Composiciones, métodos y kits para el diagnóstico de una neoplasia neuroendocrina gastroenteropancreática
ES21169154T Active ES3013599T3 (en) 2014-09-15 2015-09-15 Compositions, methods and kits for diagnosis of a gastroenteropancreatic neuroendocrine neoplasm

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES21169154T Active ES3013599T3 (en) 2014-09-15 2015-09-15 Compositions, methods and kits for diagnosis of a gastroenteropancreatic neuroendocrine neoplasm

Country Status (13)

Country Link
US (4) US10407730B2 (https=)
EP (2) EP3194618B1 (https=)
JP (2) JP6782700B2 (https=)
KR (2) KR102762958B1 (https=)
CN (1) CN107208132A (https=)
AU (3) AU2015317893B2 (https=)
CA (1) CA2959670C (https=)
DK (2) DK3929303T3 (https=)
ES (2) ES2881474T3 (https=)
IL (2) IL250867B (https=)
MX (2) MX386919B (https=)
PL (2) PL3929303T3 (https=)
WO (1) WO2016044330A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3194618B1 (en) 2014-09-15 2021-04-21 Clifton Life Sciences LLC Compositions, methods and kits for diagnosis of a gastroenteropancreatic neuroendocrine neoplasm
KR102763004B1 (ko) * 2017-05-25 2025-02-04 리퀴드 바이옵시 리서치 엘엘씨 흑색종의 검출 방법
KR20250123230A (ko) * 2017-11-30 2025-08-14 리퀴드 바이옵시 리서치 엘엘씨 유전자 발현 검정을 이용한 펩티드 수용체 방사선요법의 예측
CN108048564B (zh) * 2018-02-09 2021-03-05 中国科学院昆明动物研究所 人glt8d1基因的新用途
WO2020027732A1 (en) * 2018-07-30 2020-02-06 Agency For Science, Technology And Research Method and system for assessing fibrosis in a tissue sample
MX2022004372A (es) 2019-10-10 2022-07-27 Liquid Biopsy Res Llc Composiciones, métodos y kits para la estabilización de muestras biológicas y de arn.
FR3110764B1 (fr) * 2020-05-20 2024-05-10 Quantum Surgical Méthode de prédiction de la récidive d’une lésion par analyse d’images
CN113215255B (zh) * 2021-04-26 2022-04-05 山东天川精准医疗科技有限公司 用于肝癌早期诊断或预后的生物标记物及其用途
US20260021141A1 (en) * 2022-07-15 2026-01-22 Emendobio Inc. Strategies For Knock-Ins At APLP2 Safe Harbor Sites
KR20250080875A (ko) * 2022-09-30 2025-06-05 리퀴드 바이옵시 리서치 엘엘씨 타액에서 신경내분비암을 검출하는 방법
CN117292755B (zh) * 2023-08-09 2026-02-06 郑州大学 多模态临界边生物标志物识别方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005020795A2 (en) 2003-08-25 2005-03-10 The Johns Hopkins University Method of diagnosis and treatment of pancreatic endocrine neoplasms based on differntial gene expression analysis
CA2727082C (en) * 2008-06-12 2019-02-26 Syntaxin Limited Fusion proteins for use in suppression of acromegaly
WO2012119013A1 (en) * 2011-03-01 2012-09-07 Yale University PREDICTING GASTROENTEROPANCREATIC NEUROENDOCRINE NEOPLASMS (GEP-NENs)
EP3194618B1 (en) 2014-09-15 2021-04-21 Clifton Life Sciences LLC Compositions, methods and kits for diagnosis of a gastroenteropancreatic neuroendocrine neoplasm

Also Published As

Publication number Publication date
MX2021012347A (es) 2021-10-22
IL281355B (en) 2022-02-01
ES3013599T3 (en) 2025-04-14
DK3929303T3 (da) 2025-03-03
AU2021212151A1 (en) 2021-08-26
KR102762958B1 (ko) 2025-02-04
CA2959670C (en) 2024-02-20
IL250867B (en) 2021-03-25
US11168372B2 (en) 2021-11-09
US20160076106A1 (en) 2016-03-17
IL281355A (en) 2021-04-29
CN107208132A (zh) 2017-09-26
IL250867A0 (en) 2017-04-30
JP7157788B2 (ja) 2022-10-20
JP6782700B2 (ja) 2020-11-11
US20220325351A1 (en) 2022-10-13
EP3929303B1 (en) 2024-12-04
EP3194618A1 (en) 2017-07-26
WO2016044330A1 (en) 2016-03-24
JP2021019618A (ja) 2021-02-18
EP3929303A1 (en) 2021-12-29
AU2021212151B2 (en) 2023-08-03
EP3194618B1 (en) 2021-04-21
PL3194618T3 (pl) 2021-12-13
US10407730B2 (en) 2019-09-10
MX386919B (es) 2025-03-19
US20260043085A1 (en) 2026-02-12
KR20170045365A (ko) 2017-04-26
US20190345568A1 (en) 2019-11-14
JP2017528164A (ja) 2017-09-28
AU2015317893B2 (en) 2021-05-20
AU2023258444A1 (en) 2023-11-23
BR112017005279A2 (pt) 2017-12-12
CA2959670A1 (en) 2016-03-24
KR20250021631A (ko) 2025-02-13
US12258633B2 (en) 2025-03-25
PL3929303T3 (pl) 2025-04-28
AU2015317893A1 (en) 2017-03-23
MX2017003370A (es) 2017-11-22
DK3194618T3 (da) 2021-07-12

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