ES2877527T3 - Pautas posológicas para conjugados de anticuerpo anti-TF-fármaco - Google Patents
Pautas posológicas para conjugados de anticuerpo anti-TF-fármaco Download PDFInfo
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- ES2877527T3 ES2877527T3 ES16765958T ES16765958T ES2877527T3 ES 2877527 T3 ES2877527 T3 ES 2877527T3 ES 16765958 T ES16765958 T ES 16765958T ES 16765958 T ES16765958 T ES 16765958T ES 2877527 T3 ES2877527 T3 ES 2877527T3
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- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6843—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a material from animals or humans
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
Landscapes
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| US201562217320P | 2015-09-11 | 2015-09-11 | |
| PCT/EP2016/071336 WO2017042352A1 (en) | 2015-09-11 | 2016-09-09 | Dosing regimens for anti-tf-antibody drug-conjugates |
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| ES2877527T3 true ES2877527T3 (es) | 2021-11-17 |
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| DK3071237T3 (da) | 2013-11-21 | 2024-09-09 | Genmab As | Lyofiliseret formulering af antistoflægemiddelkonjugat |
| KR20250044949A (ko) * | 2017-11-02 | 2025-04-01 | 젠맵 에이/에스 | 항-조직 인자 항체-약물 접합체 및 암 치료에서의 그의 용도 |
| JP7653013B2 (ja) | 2018-01-04 | 2025-03-28 | アイコニック セラピューティクス リミテッド ライアビリティ カンパニー | 抗組織因子抗体、抗体薬物コンジュゲート、及び関連する方法 |
| MX2020008613A (es) * | 2018-03-07 | 2020-09-21 | Genmab As | Conjugados de anticuerpo anti-factor tisular-farmaco y su uso en el tratamiento de cancer. |
| TWI841554B (zh) | 2018-03-21 | 2024-05-11 | 丹麥商珍美寶股份有限公司 | 以鉑為主之劑與抗組織因子抗體－藥物共軛物的組合治療癌症之方法 |
| UA130009C2 (uk) | 2018-05-07 | 2025-10-15 | Генмаб А/С | Спосіб лікування раку за допомогою комбінації антитіла до pd-1 і кон'югата антитіла до тканинного фактора і лікарського засобу |
| JP2021534165A (ja) * | 2018-08-16 | 2021-12-09 | ゲンマブ エー／エス | 抗組織因子抗体−薬物コンジュゲートおよびがんの治療におけるその使用 |
| TWI844571B (zh) * | 2018-10-30 | 2024-06-11 | 丹麥商珍美寶股份有限公司 | 使用抗血管內皮生長因子（ｖｅｇｆ）抗體與抗組織因子（ｔｆ）抗體－藥物共軛體之組合以治療癌症之方法 |
| JP7406784B2 (ja) * | 2019-04-17 | 2023-12-28 | 国立大学法人金沢大学 | 卵巣癌の検出方法 |
| TW202131954A (zh) * | 2019-11-07 | 2021-09-01 | 丹麥商珍美寶股份有限公司 | 利用鉑類劑與抗組織因子抗體－藥物共軛體之組合來治療癌症之方法 |
| AU2020380732A1 (en) * | 2019-11-07 | 2022-06-02 | Genmab A/S | Methods of treating cancer with a combination of an anti-pd-1 antibody and an anti-tissue factor antibody-drug conjugate |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
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| UA109633C2 (uk) | 2008-12-09 | 2015-09-25 | Антитіло людини проти тканинного фактора | |
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| JP2021181479A (ja) | 2021-11-25 |
| JP6978409B2 (ja) | 2021-12-08 |
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| US20220265844A1 (en) | 2022-08-25 |
| EP3919081A1 (en) | 2021-12-08 |
| JP2018532715A (ja) | 2018-11-08 |
| WO2017042352A1 (en) | 2017-03-16 |
| US20190030178A1 (en) | 2019-01-31 |
| SI3347054T1 (sl) | 2021-08-31 |
| CY1124532T1 (el) | 2022-07-22 |
| HUE055109T2 (hu) | 2021-11-29 |
| EP3347054A1 (en) | 2018-07-18 |
| PL3347054T3 (pl) | 2021-11-29 |
| DK3347054T3 (da) | 2021-07-19 |
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