ES287334A1 - A procedure for the preparation of steroid compounds 5 (10) -deshidro (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of steroid compounds 5 (10) -deshidro (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES287334A1
ES287334A1 ES287334A ES287334A ES287334A1 ES 287334 A1 ES287334 A1 ES 287334A1 ES 287334 A ES287334 A ES 287334A ES 287334 A ES287334 A ES 287334A ES 287334 A1 ES287334 A1 ES 287334A1
Authority
ES
Spain
Prior art keywords
translation
carbon atoms
machine
legally binding
google translate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES287334A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES287334A1 publication Critical patent/ES287334A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Abstract

A method of preparing the steroid compounds 5 (10) -dehydro, of the general formula ** (See formula) ** wherein R represents hydrogen or a lower alkyl radical and, especially, a methyl, ethyl or propyl, X hydrogen or a lower acyl organic radical having from 1 to 18 carbon atoms, and Y hydrogen or a hydrocarbon radical containing 1 or 2 carbon atoms and, especially, a methyl, an ethyl or an ethynyl, these hydrocarbon radicals may be substituted or unsubstituted, characterized in that the corresponding delta4,9 diene compounds are subjected to a reduction by an alkali metal, or calcium , in the presence of liquid ammonia and a proton donor, and esterified, if necessary, the steroid compound 5 (10) -dehydro obtained, by the action of a functional derivative of an organic carboxylic acid having from 1 to 18 carbon atoms. (Machine-translation by Google Translate, not legally binding)
ES287334A 1962-04-25 1963-04-24 A procedure for the preparation of steroid compounds 5 (10) -deshidro (Machine-translation by Google Translate, not legally binding) Expired ES287334A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR895563A FR1380415A (en) 1962-04-25 1962-04-25 Process for the preparation of steroids having a double bond in position 5 (10)

Publications (1)

Publication Number Publication Date
ES287334A1 true ES287334A1 (en) 1963-07-16

Family

ID=8777621

Family Applications (1)

Application Number Title Priority Date Filing Date
ES287334A Expired ES287334A1 (en) 1962-04-25 1963-04-24 A procedure for the preparation of steroid compounds 5 (10) -deshidro (Machine-translation by Google Translate, not legally binding)

Country Status (7)

Country Link
AT (1) AT253696B (en)
BR (1) BR6348576D0 (en)
CH (1) CH414609A (en)
DK (1) DK105336C (en)
ES (1) ES287334A1 (en)
FR (2) FR1380415A (en)
GB (1) GB1015013A (en)

Also Published As

Publication number Publication date
AT253696B (en) 1967-04-25
BR6348576D0 (en) 1973-07-03
FR2323M (en) 1964-02-10
CH414609A (en) 1966-06-15
GB1015013A (en) 1965-12-31
FR1380415A (en) 1964-12-04
DK105336C (en) 1966-09-19

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