ES286919A1 - Procedure for the preparation of new medicines of seding, hypnotic and analgesic action (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of new medicines of seding, hypnotic and analgesic action (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES286919A1
ES286919A1 ES286919A ES286919A ES286919A1 ES 286919 A1 ES286919 A1 ES 286919A1 ES 286919 A ES286919 A ES 286919A ES 286919 A ES286919 A ES 286919A ES 286919 A1 ES286919 A1 ES 286919A1
Authority
ES
Spain
Prior art keywords
procedure
seding
hypnotic
translation
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES286919A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Danalyses & De Rech Mauvernay Centre Europeen De Rech Fondamentales & Appliquees C E R F
Original Assignee
Laboratoire Danalyses & De Rech Mauvernay Centre Europeen De Rech Fondamentales & Appliquees C E R F
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR900947A external-priority patent/FR1344901A/en
Application filed by Laboratoire Danalyses & De Rech Mauvernay Centre Europeen De Rech Fondamentales & Appliquees C E R F filed Critical Laboratoire Danalyses & De Rech Mauvernay Centre Europeen De Rech Fondamentales & Appliquees C E R F
Publication of ES286919A1 publication Critical patent/ES286919A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

"PROCEDURE FOR THE PREPARATION OF NEW MEDICINES OF SEDING, HYPNOTIC AND ANALGESIC ACTION", this procedure consisting, in a first phase, that responds to the general formula: ** (See formula) ** wherein R can represent an alkoxy or alkylenoxy group, as the following groups: ** (See formula) ** and R1 and R2 can be identical or different to represent the hydrogen or a lower alkyl group, or to form together with the nitrogen atom a heterocycle, a process characterized in that it consists, in a first phase, in hydrolyzing with concentrated sulfuric acid the 4-methoxy group of the corresponding 3,4,5-trimethoxybenzamide, and then, in a second step, reacting the 3,5-dimethoxy-4-hydroxy-benzamide obtained with an alkyl or alkenyl halide, and in collecting the resulting derivative. (Machine-translation by Google Translate, not legally binding)
ES286919A 1962-04-16 1963-04-09 Procedure for the preparation of new medicines of seding, hypnotic and analgesic action (Machine-translation by Google Translate, not legally binding) Expired ES286919A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR894584 1962-04-16
FR900947A FR1344901A (en) 1962-06-15 1962-06-15 New dialkyloxy allylbenzamides and process for their preparation

Publications (1)

Publication Number Publication Date
ES286919A1 true ES286919A1 (en) 1963-08-01

Family

ID=26195245

Family Applications (1)

Application Number Title Priority Date Filing Date
ES286919A Expired ES286919A1 (en) 1962-04-16 1963-04-09 Procedure for the preparation of new medicines of seding, hypnotic and analgesic action (Machine-translation by Google Translate, not legally binding)

Country Status (2)

Country Link
ES (1) ES286919A1 (en)
GB (1) GB964232A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4189043B2 (en) * 1996-09-30 2008-12-03 株式会社資生堂 N-acyl piperazine derivatives, antibacterial agents, anti-ulcer agents

Also Published As

Publication number Publication date
GB964232A (en) 1964-07-22

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