ES298106A1 - Cyclohexyloxycyclopropylamines - Google Patents

Cyclohexyloxycyclopropylamines

Info

Publication number
ES298106A1
ES298106A1 ES0298106A ES298106A ES298106A1 ES 298106 A1 ES298106 A1 ES 298106A1 ES 0298106 A ES0298106 A ES 0298106A ES 298106 A ES298106 A ES 298106A ES 298106 A1 ES298106 A1 ES 298106A1
Authority
ES
Spain
Prior art keywords
formula
taken
group
acid addition
see formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0298106A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES298106A1 publication Critical patent/ES298106A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedure for the preparation of new cyclic amines, of the formula ** (See formula) ** wherein R1, R2, R3, R4, R5 and R6 are taken from the group consisting of hydrogen and lower alkyl; and Z is taken from the group consisting of oxygen, sulfur and lower oxyalkyl, and its acid addition salts characterized in that it consists in subjecting an isocyanate of the formula ** (See formula) ** where R1, R2, R3, R6 and Z have the same meaning as before, to hydrolysis, if desired after reaction with an alcohol, and, if desired, to alkylate the obtained primary amine and/or convert it into an acid addition salt. (Machine-translation by Google Translate, not legally binding)
ES0298106A 1963-03-29 1964-03-28 Cyclohexyloxycyclopropylamines Expired ES298106A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US269138A US3209026A (en) 1963-03-29 1963-03-29 Cyclohexyloxycyclopropylamines

Publications (1)

Publication Number Publication Date
ES298106A1 true ES298106A1 (en) 1964-09-01

Family

ID=23025958

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0298106A Expired ES298106A1 (en) 1963-03-29 1964-03-28 Cyclohexyloxycyclopropylamines

Country Status (6)

Country Link
US (1) US3209026A (en)
BE (1) BE645625A (en)
BR (1) BR6457834D0 (en)
ES (1) ES298106A1 (en)
FR (1) FR3616M (en)
NL (1) NL6403295A (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3687996A (en) * 1969-06-16 1972-08-29 Ciba Geigy Corp Process for the production of octahydro-1,2,4-methenopentalenyl-(5)exo-isocyanate
CA1117127A (en) * 1978-06-27 1982-01-26 Janet A. Day Derivatives of 3-azabicyclo(3.1.0)hexane and a process for their preparation
US4889874A (en) * 1986-07-07 1989-12-26 E. R. Squibb & Sons, Inc. Hydroxamic acid derivatives and method of using same
US5015765A (en) * 1988-03-24 1991-05-14 Fmc Corporation Process for isolating hydroxamic acids

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3014966A (en) * 1958-01-29 1961-12-26 Abbott Lab Catalytic hydrogenation of phenylalkyl-beta-amines
US3079403A (en) * 1960-09-19 1963-02-26 Smith Kline French Lab Process for preparing amines
US3059020A (en) * 1960-09-30 1962-10-16 Smith Kline French Lab Substituted cyclopropylamines and cyclopropylcarbamates

Also Published As

Publication number Publication date
US3209026A (en) 1965-09-28
BE645625A (en) 1964-09-24
FR3616M (en) 1965-10-18
BR6457834D0 (en) 1973-08-28
NL6403295A (en) 1964-09-30

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