ES286802A1 - Procedimiento de preparacion de compuestos de 1-acil-1-[2-(azaciclil) etil]-2-(5-nitrofurfurilideno) hidrazinas - Google Patents
Procedimiento de preparacion de compuestos de 1-acil-1-[2-(azaciclil) etil]-2-(5-nitrofurfurilideno) hidrazinasInfo
- Publication number
- ES286802A1 ES286802A1 ES0286802A ES286802A ES286802A1 ES 286802 A1 ES286802 A1 ES 286802A1 ES 0286802 A ES0286802 A ES 0286802A ES 286802 A ES286802 A ES 286802A ES 286802 A1 ES286802 A1 ES 286802A1
- Authority
- ES
- Spain
- Prior art keywords
- reacting
- prepared
- group
- nitrofurfural
- semicarbazone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 title 1
- 150000002429 hydrazines Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 8
- -1 1-piperidyl Chemical group 0.000 abstract 6
- SXINBFXPADXIEY-UHFFFAOYSA-N 5-Nitrofurfural Chemical compound [O-][N+](=O)C1=CC=C(C=O)O1 SXINBFXPADXIEY-UHFFFAOYSA-N 0.000 abstract 5
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 4
- 125000001118 alkylidene group Chemical group 0.000 abstract 4
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 3
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 3
- NHXGSDWKTVZWPB-UHFFFAOYSA-N 1-(benzylideneamino)-1-(2-chloroethyl)urea Chemical compound ClCCN(C(N)=O)N=CC1=CC=CC=C1 NHXGSDWKTVZWPB-UHFFFAOYSA-N 0.000 abstract 2
- 125000004105 2-pyridyl group Chemical group N1=C([*])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
- OAKJQQAXSVQMHS-UHFFFAOYSA-N Hydrazine Chemical compound NN OAKJQQAXSVQMHS-UHFFFAOYSA-N 0.000 abstract 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 2
- 239000011707 mineral Substances 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- QPEKEKCWYGXELX-UHFFFAOYSA-N 1-(benzylideneamino)-1-(2-hydroxyethyl)urea Chemical compound OCCN(C(N)=O)N=CC1=CC=CC=C1 QPEKEKCWYGXELX-UHFFFAOYSA-N 0.000 abstract 1
- NXFWQNVPCNWZOH-UHFFFAOYSA-N 1-(benzylideneamino)-1-(2-morpholin-4-ylethyl)urea Chemical compound N1(CCOCC1)CCN(C(N)=O)N=CC1=CC=CC=C1 NXFWQNVPCNWZOH-UHFFFAOYSA-N 0.000 abstract 1
- IXTVCJVZBNUTQV-UHFFFAOYSA-N 1-(benzylideneamino)-1-(2-piperidin-1-ylethyl)urea Chemical compound N1(CCCCC1)CCN(C(N)=O)N=CC1=CC=CC=C1 IXTVCJVZBNUTQV-UHFFFAOYSA-N 0.000 abstract 1
- BWVQKKXMJZHHMY-UHFFFAOYSA-N Cl.C(C1=CC=CC=C1)=NN1C(OCC1)=N Chemical compound Cl.C(C1=CC=CC=C1)=NN1C(OCC1)=N BWVQKKXMJZHHMY-UHFFFAOYSA-N 0.000 abstract 1
- 101100448208 Human herpesvirus 6B (strain Z29) U69 gene Proteins 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 abstract 1
- 230000000397 acetylating effect Effects 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000007857 hydrazones Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000000590 parasiticidal effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- GKKCIDNWFBPDBW-UHFFFAOYSA-M potassium cyanate Chemical compound [K]OC#N GKKCIDNWFBPDBW-UHFFFAOYSA-M 0.000 abstract 1
- 244000144977 poultry Species 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- 239000008096 xylene Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/70—Nitro radicals
- C07D307/71—Nitro radicals attached in position 5
- C07D307/72—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2
- C07D307/74—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by hydrazino or hydrazono or such substituted radicals
- C07D307/75—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by hydrazino or hydrazono or such substituted radicals having carboxylic acyl radicals or their thio or nitrogen analogues directly attached to the hydrazino or hydrazono radical, e.g. hydrazides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/70—Nitro radicals
- C07D307/71—Nitro radicals attached in position 5
- C07D307/72—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2
- C07D307/74—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by hydrazino or hydrazono or such substituted radicals
- C07D307/76—Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by hydrazino or hydrazono or such substituted radicals having carbonic acyl radicals or their thio or nitrogen analogues directly attached to the hydrazino or hydrazono radical, e.g. semicarbazides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US185243A US3206461A (en) | 1962-04-05 | 1962-04-05 | 1-acyl-1-[2-(azacyclyl) ethyl]-2-(5-nitrofurfurylidene)hydrazines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES286802A1 true ES286802A1 (es) | 1963-08-01 |
Family
ID=22680188
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES0286802A Expired ES286802A1 (es) | 1962-04-05 | 1963-04-05 | Procedimiento de preparacion de compuestos de 1-acil-1-[2-(azaciclil) etil]-2-(5-nitrofurfurilideno) hidrazinas |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3206461A (en, 2012) |
| BE (1) | BE630615A (en, 2012) |
| BR (1) | BR6348265D0 (en, 2012) |
| CH (1) | CH446381A (en, 2012) |
| DE (1) | DE1196656B (en, 2012) |
| DK (2) | DK107480C (en, 2012) |
| ES (1) | ES286802A1 (en, 2012) |
| FR (1) | FR2511M (en, 2012) |
| GB (1) | GB1040725A (en, 2012) |
| NL (1) | NL291189A (en, 2012) |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2663710A (en) * | 1950-05-29 | 1953-12-22 | Eaton Lab Inc | Series of nitrofuran compounds comprising 5-nitro-2-furyl 2-dialkyl-aminoalkyl ketone semicarbazone salts |
| US2726241A (en) * | 1954-01-15 | 1955-12-06 | Norwich Pharma Co | New series of nitrofurans |
| US2802002A (en) * | 1956-07-18 | 1957-08-06 | Norwich Pharma Co | Series of new nu-(5-nitro-2-furyl) alkylidene-3-amino-5-tertiaryamino-methyl-2-oxazolidones and the preparation thereof |
| US3012032A (en) * | 1958-05-07 | 1961-12-05 | Norwich Pharma Co | 2-[2-(4-pyridyl)-ethyl]-6-methyl-4, 5-dihydro-3-pyridazinone |
| US3043853A (en) * | 1960-02-23 | 1962-07-10 | Norwich Pharma Co | New 1-acyl-1-(2-cyano-ethyl)-2-(5-nitrofurylidene)hydrazines and the preparation thereof |
| AT218014B (de) * | 1960-02-23 | 1961-11-10 | Norwich Pharma Co | Verfahren zur Herstellung neuer 1-Acyl-1-(β-chloräthyl)-2-(5'-nitrofurfuryliden)-hydrazine |
| NL272959A (en, 2012) * | 1960-12-27 |
-
0
- BE BE630615D patent/BE630615A/xx unknown
- NL NL291189D patent/NL291189A/xx unknown
-
1962
- 1962-04-05 US US185243A patent/US3206461A/en not_active Expired - Lifetime
-
1963
- 1963-02-28 DE DEN22824A patent/DE1196656B/de active Pending
- 1963-03-28 GB GB12284/63A patent/GB1040725A/en not_active Expired
- 1963-04-02 CH CH418363A patent/CH446381A/de unknown
- 1963-04-04 DK DK157063AA patent/DK107480C/da active
- 1963-04-04 DK DK433564AA patent/DK105869C/da active
- 1963-04-05 FR FR930610A patent/FR2511M/fr active Active
- 1963-04-05 ES ES0286802A patent/ES286802A1/es not_active Expired
- 1963-04-05 BR BR148265/63A patent/BR6348265D0/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US3206461A (en) | 1965-09-14 |
| DE1196656B (de) | 1965-07-15 |
| BR6348265D0 (pt) | 1973-07-03 |
| BE630615A (en, 2012) | |
| FR2511M (fr) | 1964-05-04 |
| CH446381A (de) | 1967-11-15 |
| DK107480C (da) | 1967-06-05 |
| DK105869C (da) | 1966-11-21 |
| GB1040725A (en) | 1966-09-01 |
| NL291189A (en, 2012) |
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