ES2864681T3 - Tratamiento del cáncer hematológico refractario a un agente contra el cáncer - Google Patents
Tratamiento del cáncer hematológico refractario a un agente contra el cáncer Download PDFInfo
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- ES2864681T3 ES2864681T3 ES13860034T ES13860034T ES2864681T3 ES 2864681 T3 ES2864681 T3 ES 2864681T3 ES 13860034 T ES13860034 T ES 13860034T ES 13860034 T ES13860034 T ES 13860034T ES 2864681 T3 ES2864681 T3 ES 2864681T3
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| PCT/US2013/073667 WO2014089483A1 (en) | 2012-12-07 | 2013-12-06 | Methods and compositions for treatment of cancer |
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| JP2016520321A (ja) * | 2013-05-31 | 2016-07-14 | オンコノバ・セラピューティックス・インコーポレーテッド | 骨髄異形成症候群又は関連障害を有する患者においてキナーゼ阻害剤の治療効能を予測するための方法及び組成物 |
| US10098862B1 (en) * | 2017-04-13 | 2018-10-16 | Onconova Therapeutics, Inc. | Formulations with enhanced stability and bioavailability for administration of (E)-2,6-dialkoxystyryl 4-substituted benzylsulfones |
| US12156856B2 (en) | 2017-04-13 | 2024-12-03 | Traws Pharma, Inc. | Formulation of (e)-2,4,6-trimethoxystyryl-3-[(carboxymethyl)amino]-4-methoxybenzylsulphone with enhanced stability and bioavailability |
| US11382877B2 (en) | 2017-04-13 | 2022-07-12 | Onconova Therapeutics, Inc. | Formulation of (E)-2,4,6-trimethoxystyryl-3-[(carboxymethyl)amino]-4-methoxybenzylsulphone with enhanced stability and bioavailability |
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| CZ299718B6 (cs) | 1997-10-03 | 2008-10-29 | Temple University - Of The Commonwealth System Ofhigher Education | Styrylsulfonová sloucenina a farmaceutický prostredek ji obsahující |
| US6548553B2 (en) | 1997-10-03 | 2003-04-15 | Temple University-Of The Commonwealth System Of Higher Education | Styryl sulfone anticancer agents |
| US6201154B1 (en) | 1999-03-31 | 2001-03-13 | Temple University-Of The Commonwealth Of Higher Education | Z-styryl sulfone anticancer agents |
| US6762207B1 (en) | 1999-04-02 | 2004-07-13 | Temple University - Of The Commonwealth System Of Higher Education | (E)-styryl sulfone anticancer agents |
| US6541475B2 (en) | 2000-04-14 | 2003-04-01 | Temple University - Of The Commonwealth System Of Higher Education | α, β-unsaturated sulfones for treating proliferative disorders |
| US6486210B2 (en) | 2000-04-14 | 2002-11-26 | Temple University—Of the Commonwealth System of Higher Education | Substituted styryl benzylsulfones for treating proliferative disorders |
| WO2002028828A1 (en) | 2000-10-05 | 2002-04-11 | Temple University - Of The Commonwealth System Of Higher Education | Substituted (e)-styryl benzylsulfones for treating proliferative disorders |
| US6833480B2 (en) | 2001-02-27 | 2004-12-21 | Temple University - Of The Commonwealth System Of Higher Education | (Z)-styrylbenzylsulfones and pharmaceutical uses thereof |
| MXPA04008356A (es) | 2002-02-28 | 2005-09-12 | Univ Temple | (e)-2,6-dialcoxiestiril bencilsulfonas sustituidas con un grupo amino y en la posicion 4 para tratar trastornos poliferativos. |
| ATE497768T1 (de) | 2004-07-19 | 2011-02-15 | Onconova Therapeutics Inc | Formulierungen für die parenterale verabreichung von (e)-2,6-dialkoxystryryl 4-substituierten benzylsulfonen |
| WO2008088803A2 (en) | 2007-01-16 | 2008-07-24 | Onconova Therapeutics, Inc. | Formulations for parenteral administration of (e)-2,6-dialkoxystyryl 4-substituted benzylsulfones |
| CA2721722C (en) * | 2008-04-17 | 2015-12-08 | The Johns Hopkins University | On01910.na enhances chemotherapeutic agent activity in drug-resistant tumors |
| NZ595382A (en) * | 2009-03-23 | 2014-02-28 | Ambit Biosciences Corp | Combination therapy involving n-(5-(tert-butyl-isoxazol-3-yl)-n’-{ 4-(7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl} urea |
| US20140120083A1 (en) * | 2012-11-01 | 2014-05-01 | Infinity Pharmaceuticals, Inc. | Treatment of cancers using pi3 kinase isoform modulators |
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| US10576050B2 (en) | 2020-03-03 |
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| WO2014089483A1 (en) | 2014-06-12 |
| EP2928456A4 (en) | 2016-08-24 |
| US20150313859A1 (en) | 2015-11-05 |
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