ES285854A1 - Un procedimiento para fabricar derivados benzodiazepínicos - Google Patents

Un procedimiento para fabricar derivados benzodiazepínicos

Info

Publication number
ES285854A1
ES285854A1 ES285854A ES285854A ES285854A1 ES 285854 A1 ES285854 A1 ES 285854A1 ES 285854 A ES285854 A ES 285854A ES 285854 A ES285854 A ES 285854A ES 285854 A1 ES285854 A1 ES 285854A1
Authority
ES
Spain
Prior art keywords
represents hydrogen
alkyl
translation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES285854A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US240750A external-priority patent/US3340253A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES285854A1 publication Critical patent/ES285854A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/20—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24—Oxygen atoms
    • C07D243/26—Preparation from compounds already containing the benzodiazepine skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Inductance-Capacitance Distribution Constants And Capacitance-Resistance Oscillators (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ES285854A 1962-03-09 1963-03-08 Un procedimiento para fabricar derivados benzodiazepínicos Expired ES285854A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17855162A 1962-03-09 1962-03-09
US240750A US3340253A (en) 1962-11-28 1962-11-28 Preparation of certain benzodiazepine compounds

Publications (1)

Publication Number Publication Date
ES285854A1 true ES285854A1 (es) 1963-08-16

Family

ID=26874429

Family Applications (1)

Application Number Title Priority Date Filing Date
ES285854A Expired ES285854A1 (es) 1962-03-09 1963-03-08 Un procedimiento para fabricar derivados benzodiazepínicos

Country Status (9)

Country Link
BE (1) BE629227A (US07754267-20100713-C00017.png)
CA (1) CA976547A (US07754267-20100713-C00017.png)
CH (2) CH457464A (US07754267-20100713-C00017.png)
DE (4) DE1545957A1 (US07754267-20100713-C00017.png)
DK (1) DK127507B (US07754267-20100713-C00017.png)
ES (1) ES285854A1 (US07754267-20100713-C00017.png)
GB (2) GB1013229A (US07754267-20100713-C00017.png)
NL (3) NL7010712A (US07754267-20100713-C00017.png)
SE (2) SE328583B (US07754267-20100713-C00017.png)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES405260A1 (es) * 1972-07-28 1975-07-01 Stabilimenti Chim Farmac Riuni Procedimiento para la preparacion de 3-hidroxi-5-aril-7- sustituidos-1, 3-dihidro-2h-1, 4-benzodiacepin-2-onas.
FR2269349B1 (US07754267-20100713-C00017.png) * 1974-04-30 1979-03-16 Ferrer Labor
DE3413592C2 (de) * 1984-04-11 1986-06-05 Dolorgiet GmbH & Co KG, 5205 St Augustin Arzneimittel enthaltend 5-(2-Fluorphenyl)-1,3-dihydro-3-hydroxy-1-methyl-7-nitro-2H-1,4-benzodiazepin-2-on
DK287185A (da) * 1984-06-26 1986-02-24 Merck & Co Inc Benzodiazepinderivat og farmaceutisk praeparat indeholdende et saadantderivat

Also Published As

Publication number Publication date
DE1545957A1 (de) 1969-12-11
DK127507B (da) 1973-11-19
CA976547A (en) 1975-10-21
BE629227A (fr) 1963-10-21
NL289735A (US07754267-20100713-C00017.png)
SE361174B (US07754267-20100713-C00017.png) 1973-10-22
DE1445873A1 (de) 1969-04-10
GB1013900A (en) 1965-12-22
SE328583B (US07754267-20100713-C00017.png) 1970-09-21
DE1545956A1 (de) 1969-11-20
NL7010712A (US07754267-20100713-C00017.png) 1970-10-26
CH442326A (de) 1967-08-31
GB1013229A (en) 1965-12-15
NL7010711A (US07754267-20100713-C00017.png) 1970-10-26
DE1545955A1 (de) 1969-11-20
CH457464A (de) 1968-06-15

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