ES2843511T3 - Métodos para reducir las concentraciones en sangre de triglicéridos, colesterol total y lipoproteínas de baja densidad - Google Patents

Métodos para reducir las concentraciones en sangre de triglicéridos, colesterol total y lipoproteínas de baja densidad Download PDF

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Publication number
ES2843511T3
ES2843511T3 ES14829314T ES14829314T ES2843511T3 ES 2843511 T3 ES2843511 T3 ES 2843511T3 ES 14829314 T ES14829314 T ES 14829314T ES 14829314 T ES14829314 T ES 14829314T ES 2843511 T3 ES2843511 T3 ES 2843511T3
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Spain
Prior art keywords
compound
metabolite
formula
ester
subject
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ES14829314T
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English (en)
Spanish (es)
Inventor
Kazuko Matsuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicinova Inc
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Medicinova Inc
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
ES14829314T 2013-07-25 2014-07-23 Métodos para reducir las concentraciones en sangre de triglicéridos, colesterol total y lipoproteínas de baja densidad Active ES2843511T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361858450P 2013-07-25 2013-07-25
PCT/US2014/047797 WO2015013395A1 (en) 2013-07-25 2014-07-23 Methods for reducing triglyceride, total cholesterol and low density lipoprotein blood levels

Publications (1)

Publication Number Publication Date
ES2843511T3 true ES2843511T3 (es) 2021-07-19

Family

ID=52391020

Family Applications (1)

Application Number Title Priority Date Filing Date
ES14829314T Active ES2843511T3 (es) 2013-07-25 2014-07-23 Métodos para reducir las concentraciones en sangre de triglicéridos, colesterol total y lipoproteínas de baja densidad

Country Status (9)

Country Link
US (2) US20150031769A1 (https=)
EP (1) EP3024454B1 (https=)
JP (1) JP6363192B2 (https=)
KR (1) KR102352728B1 (https=)
CN (1) CN105407884B (https=)
BR (1) BR112016001400B1 (https=)
CA (1) CA2917780C (https=)
ES (1) ES2843511T3 (https=)
WO (1) WO2015013395A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3217719A1 (en) 2021-05-28 2022-12-01 Kazuko Matsuda Phenoxyalkylcarboxylic acid derivatives and their use in lowering triglyceride levels
CN120379658A (zh) 2022-11-30 2025-07-25 花王株式会社 发痒的预防或改善剂

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2585246A1 (fr) 1985-07-26 1987-01-30 Cortial Procede d'obtention de formes pharmaceutiques solides a liberation prolongee
US4788055A (en) 1985-12-09 1988-11-29 Ciba-Geigy Corporation Resinate sustained release dextromethorphan composition
GB8613689D0 (en) 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
GB8613688D0 (en) 1986-06-05 1986-07-09 Euro Celtique Sa Pharmaceutical composition
US4816264A (en) 1986-06-06 1989-03-28 Warner-Lambert Company Sustained release formulations
US4985585A (en) 1988-03-07 1991-01-15 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process for their preparations
US4996047A (en) 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes
CA2002492A1 (en) 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5290812A (en) 1991-01-18 1994-03-01 Kyorin Pharmaceutical Co., Ltd. Phenoxyalkylcarboxylic acid derivatives and process of preparing the same
US7064146B2 (en) 2003-06-24 2006-06-20 Medicinova, Inc. Pharmaceutical compositions of isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid and methods of use
US7060854B2 (en) 2003-06-24 2006-06-13 Medicinova, Inc. Process for making polymorphic form A of 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid
US7429617B2 (en) * 2004-04-27 2008-09-30 Medicinova, Inc. Phenoxyalkycarboxylic acid derivatives in the treatment of interstitial cystitis
EP1781303A4 (en) * 2004-06-30 2008-07-02 Combinatorx Inc METHOD AND REAGENTS FOR THE TREATMENT OF METABOLISM DISEASES
PT1894576E (pt) * 2005-06-08 2011-07-29 Kowa Co Novo agente redutor dos níveis de triglicéridos
WO2009002746A1 (en) * 2007-06-22 2008-12-31 Decode Genetics Ehf. Dosing schedules of leukotriene synthesis inhibitors for human therapy

Also Published As

Publication number Publication date
JP6363192B2 (ja) 2018-07-25
CN105407884B (zh) 2019-04-30
EP3024454A1 (en) 2016-06-01
US9358217B2 (en) 2016-06-07
WO2015013395A1 (en) 2015-01-29
BR112016001400B1 (pt) 2023-02-28
US20150031769A1 (en) 2015-01-29
EP3024454A4 (en) 2017-03-15
US20150080471A1 (en) 2015-03-19
CA2917780C (en) 2023-01-24
CA2917780A1 (en) 2015-01-29
BR112016001400A8 (pt) 2020-01-14
EP3024454B1 (en) 2020-10-21
JP2016525546A (ja) 2016-08-25
KR20160034324A (ko) 2016-03-29
BR112016001400A2 (pt) 2017-07-25
CN105407884A (zh) 2016-03-16
KR102352728B1 (ko) 2022-01-18

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