ES280760A1 - Un metodo de producir los racematos y los estereoisëmeros, incluyendo los mesoisëmeros de 2,3-0-acetales ciclicos y 2,3-0-cetales ciclicos de butano -1,2,3,4-tetrol-1,4-di- (metano sulfonato) - Google Patents

Un metodo de producir los racematos y los estereoisëmeros, incluyendo los mesoisëmeros de 2,3-0-acetales ciclicos y 2,3-0-cetales ciclicos de butano -1,2,3,4-tetrol-1,4-di- (metano sulfonato)

Info

Publication number
ES280760A1
ES280760A1 ES0280760A ES280760A ES280760A1 ES 280760 A1 ES280760 A1 ES 280760A1 ES 0280760 A ES0280760 A ES 0280760A ES 280760 A ES280760 A ES 280760A ES 280760 A1 ES280760 A1 ES 280760A1
Authority
ES
Spain
Prior art keywords
threitol
methane sulphonate
methane
tetrol
butane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0280760A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Pharma AS
Original Assignee
Leo Pharmaceutical Products Ltd AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharmaceutical Products Ltd AS filed Critical Leo Pharmaceutical Products Ltd AS
Publication of ES280760A1 publication Critical patent/ES280760A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un método de producir los racematos y los estereoisomeros, incluyendo los mesoisomeros, de 2,3-0-acetales cliclicos y 2,3-0-cetales cicliclos de butano -1,2,3,4-tetrol-1,4-Di-(METANO SULFONATO) de fórmula general: **FIGURA** en donde R1 y R2 son hidrógeno y grupos sustituidos y sin sustituir alifáticos, alicíclicos, aromáticos y heterocíclicos, ó R{sub,1} y R{sub,2} forman juntos un anillo alicíclico sustituído o sin sustituir, caracterizado en que el racemato o la forma estereoisomérica deseada del correspondiente 2,3-0-acetal cíclico o 2,3-0-cetal cíclico de butano -1,2,3,4-tetrol se hace reaccionar con un derivado funcional reactivo de ácido metano sulfónico, tal como el anhídrido del ácido metano-sulfónico o un halogenuro de metano sulfonilo, después de lo cual se recupera el 1,4-disulfonato así obtenido.
ES0280760A 1961-09-15 1962-09-13 Un metodo de producir los racematos y los estereoisëmeros, incluyendo los mesoisëmeros de 2,3-0-acetales ciclicos y 2,3-0-cetales ciclicos de butano -1,2,3,4-tetrol-1,4-di- (metano sulfonato) Expired ES280760A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB33247/61A GB976534A (en) 1961-09-15 1961-09-15 Cyclic 2,3-o-acetals and 2,3-o-ketals of butanetetrol esters

Publications (1)

Publication Number Publication Date
ES280760A1 true ES280760A1 (es) 1963-02-01

Family

ID=10350441

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0280760A Expired ES280760A1 (es) 1961-09-15 1962-09-13 Un metodo de producir los racematos y los estereoisëmeros, incluyendo los mesoisëmeros de 2,3-0-acetales ciclicos y 2,3-0-cetales ciclicos de butano -1,2,3,4-tetrol-1,4-di- (metano sulfonato)

Country Status (7)

Country Link
US (1) US3246012A (es)
BE (1) BE622353A (es)
CH (1) CH417630A (es)
DK (1) DK114489B (es)
ES (1) ES280760A1 (es)
FR (2) FR1575503A (es)
GB (1) GB976534A (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3948953A (en) * 1969-08-05 1976-04-06 Texaco Inc. Dioxolane derivatives having surfactant properties
US4060532A (en) * 1972-03-15 1977-11-29 Ici United States Inc. Halogenated dioxolane tranquilizers
US3996376A (en) * 1972-03-28 1976-12-07 Ici United States Inc. Halogenated dioxolane tranquilizers
US4591601A (en) * 1985-04-12 1986-05-27 Mcneilab, Inc. Anticonvulsant dioxolane methane sulfamates
CN103896903A (zh) * 2012-12-26 2014-07-02 北京奥得赛化学股份有限公司 制备和纯化2,3-o-异亚丙基苏糖醇的方法
WO2019043587A2 (en) 2017-08-31 2019-03-07 Fresenius Kabi Oncology Ltd. PROCESS FOR THE PREPARATION OF TREOSULFAN

Also Published As

Publication number Publication date
FR2393M (fr) 1964-03-09
CH417630A (de) 1966-07-31
BE622353A (es)
FR1575503A (es) 1969-07-25
DK114489B (da) 1969-07-07
GB976534A (en) 1964-11-25
US3246012A (en) 1966-04-12

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